Abstract: The present invention provides automated methods for expanding TILs and producing therapeutic populations of TILs, including novel tissue culture devices and automated methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs.

Abstract: An audio-visual display device for pictorial artwork is disclosed. The preferred embodiment has a universal backbox which contains a lightboard capable of lighting up any and/or all sections of a pictorial artwork placed above it, a hidden electric eye for detecting when the viewer wishes to see a snippet of an audio-visual sequence, a speaker, a memory for storing snippets of an audio sequence, and a microprocessor which receives signals from the electric eye and controls the speaker and the lightboard in accordance with an audio-visual sequence which brings to life the pictorial artwork.

Abstract: An audio-visual display device for pictorial artwork is disclosed. The preferred embodiment has a universal backbox which contains a lightboard capable of lighting up any and/or all sections of a pictorial artwork placed above it, a hidden electric eye for detecting when the viewer wishes to see a snippet of an audio-visual sequence, a speaker, a memory for storing snippets of an audio sequence, and a microprocessor which receives signals from the electric eye and controls the speaker and the lightboard in accordance with an audio-visual sequence which brings to life the pictorial artwork.