Patents by Inventor Richard B. Rosen

Richard B. Rosen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200000740
    Abstract: A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma. The pharmaceutically effective amount of zeaxanthin is generally above about 0.5 mg/kg/d to about 20 mg/kg/d.
    Type: Application
    Filed: February 28, 2019
    Publication date: January 2, 2020
    Applicant: The New York Eye and Ear Infirmary
    Inventors: Richard B. ROSEN, Dan-Ning HU
  • Publication number: 20180318235
    Abstract: A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma. The pharmaceutically effective amount of zeaxanthin is generally above about 0.5 mg/kg/d to about 20 mg/kg/d.
    Type: Application
    Filed: May 8, 2018
    Publication date: November 8, 2018
    Inventors: Richard B. Rosen, Dan-Ning Hu
  • Publication number: 20180036257
    Abstract: A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma. The pharmaceutically effective amount of zeaxanthin is generally above about 0.5 mg/kg/d to about 20 mg/kg/d.
    Type: Application
    Filed: October 16, 2017
    Publication date: February 8, 2018
    Inventors: Richard B. Rosen, Dan-Ning Hu
  • Publication number: 20170014354
    Abstract: A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma. The pharmaceutically effective amount of zeaxanthin is generally above about 0.5 mg/kg/d to about 20 mg/kg/d.
    Type: Application
    Filed: September 27, 2016
    Publication date: January 19, 2017
    Inventors: Richard B. Rosen, Dan-Ning Hu
  • Publication number: 20150209303
    Abstract: A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma. The pharmaceutically effective amount of zeaxanthin is generally above about 0.5 mg/kg/d to about 20 mg/kg/d.
    Type: Application
    Filed: February 12, 2015
    Publication date: July 30, 2015
    Inventors: Richard B. Rosen, Dan-Ning Hu
  • Publication number: 20130302319
    Abstract: A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma. The pharmaceutically effective amount of zeaxanthin is generally above about 0.5 mg/kg/d to about 20 mg/kg/d.
    Type: Application
    Filed: March 15, 2013
    Publication date: November 14, 2013
    Applicant: The New York Eye and Ear Infirmary
    Inventors: Richard B. Rosen, Dan-Ning Hu
  • Publication number: 20040176752
    Abstract: A system and method for exposing ocular tissue to a beam of electromagnetic radiation tuned to an NIR wavelength between about 1380 nm and about 1600 nm in the water absorption band. The laser energy is absorbed by the water, which in turn, transfers the energy to collagen molecules. The helical collagen molecules partially denature and then re-nature to form a weld across the region of the tissues to be joined. In a preferred embodiment, the electromagnetic radiation originates from a laser. The lasers may be Cr4+ doped crystals, Erbium fibers, and alloys of semiconductor laser diodes.
    Type: Application
    Filed: March 6, 2003
    Publication date: September 9, 2004
    Inventors: Robert R. Alfano, Tapan K. Gayen, Steven A. McCormick, Richard B. Rosen, Alvin Katz, Howard E. Savage
  • Publication number: 20020095257
    Abstract: A system to detect eye disease in which monochromatic laser light is directed into the vitreous humor after passing through the front of the eye. A very sensitive detection system then detects the light scattered from the vitreous humor as it exits the eye. The light is scattered at a wavelength different from that of the laser in a manner known as Raman scattering. The wavelength of the Raman scattered photons are shifted by vibrational modes of the molecules, and this shift is a characteristic feature of the molecules interacting with the light. In this way, the Raman scattered light is essentially imprinted with a fingerprint of relevant molecules. As it exits the eye, this Raman scattered light can be separated from other types of scattered light and then routed to a detection system, wherein the results are calibrated against actual standards for the particular vitreous substances being analyzed.
    Type: Application
    Filed: March 26, 2001
    Publication date: July 18, 2002
    Inventors: Richard B. Rosen, Erik F. Kruger, Alvin Katz, Robert R. Alfano