Abstract: Disclosed herein are B cell maturation antigen binding proteins with improved binding affinities and improved ability to mediate killing of cancer cells expressing B cell maturation antigen (BCMA). Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of treatment of a cancer or a metastasis thereof using such formulations are further provided.

Abstract: Disclosed herein are MSLN binding proteins with improved binding affinities and improved ability to mediate T cell dependent killing of cancer cells expressing mesothelin. Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of using such formulations are further provided.

Abstract: Provided herein are combinations or compositions comprising immunomodulators and immune cell engaging proteins. Also provided herein are methods of use thereof, such as methods of treatment by administering the combinations or compositions comprising immunomodulators and immune cell engaging proteins to a subject. The method may be used to treat a cancer in the subject.

Abstract: Threat exchange information protection can include receiving security information from a number of participants of a threat exchange community, wherein a portion of the received security information is encoded with pseudonyms by each of the number of participants, analyzing the security information collectively from the number of participants, wherein the portion of the received security information remains encoded, and sending analysis results to each of the number of participants, wherein the analysis results include information relating to the portion.

Abstract: Threat exchange information protection can include receiving security information from a number of participants of a threat exchange community, wherein a portion of the received security information is encoded with pseudonyms by each of the number of participants, analyzing the security information collectively from the number of participants, wherein the portion of the received security information remains encoded, and sending analysis results to each of the number of participants, wherein the analysis results include information relating to the portion.

Abstract: A double acting concrete pump includes a pair of pump cylinders with a piston slidable back and forth in each cylinder, the pistons being driven in opposite directions, a connecting manifold connecting each of the cylinder outlets to a source of cement via separate pumping chambers, and a separate, removable discharge manifold for connecting the pumping chamber outlets to a delivery outlet. The discharge manifold has a discharge chamber with a pair of inlets connected to the respective pumping chamber outlets, and a single discharge outlet, with an outlet control valve in the discharge chamber for alternately isolating the flow from each of the pumping chambers to the discharge outlet in response to the pumping action.

Abstract: A pump for applying pre-mixed cement, and similar mud-like flowable materials, employs power driven oppositely reciprocating pistons sliding in a pair of cylinders for pumping action. A control manifold, having a single cement discharge outlet, interconnects combined suction and discharge outlets of each pump cylinder with a cement supply hopper manifold inlet. Two manifold pump response chambers, and a single discharge chamber in flow communication with one another within the manifold, together with associated valving within each chamber, provides for unidirectional flow of cement under pressure from the manifold discharge outlet solely in response to the movement of the pistons within the pump cylinders. The pump response chamber valves have adjustable valve openings so that the pump may be employed with flowable materials of varying viscosity.

Abstract: A double acting concrete pump having a pair of interconnected mud pistons driven by a reversing hydraulic actuator, which is reversed by the piston motion at the end of each stroke, and has a pressure relief to avoid bottoming at the end of a stroke. The mud pistons slide in cylinders which are lubricated and cleaned by a supply of lubricant circulated between the cylinders by the piston action. Concrete or similar mud-like material is drawn from a hopper and pumped out through a common outlet.