Patents by Inventor Richard D. Bruce

Richard D. Bruce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6399137
    Abstract: The present invention provides a stable foodstuffs which contain a cholesterol lowering amount of a sterol or stanol ester, crystal fat inhibitors and emulsifiers. The foodstuffs, including salad dressings are stable even when refrigerated.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: June 4, 2002
    Assignee: McNeil-PPC, Inc.
    Inventors: Clemence K. Dartey, John D. Higgins, III, Richard D. Bruce, Brid T. Burruano
  • Patent number: 6387411
    Abstract: A method for preparing sterol/stanol and sterol/stanol ester compositions with improved dispersibility is provided by co-melting the sterol/stanol and/or sterol/stanol ester with highly branched hydrocarbons and then grinding the resulting product. A method for preparing the compounds is also disclosed. The ground compound is suitable for formulating into orally administered products suitable for control of blood serum cholesterol.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: May 14, 2002
    Assignee: McNeil-PPC, Inc.
    Inventors: Richard D. Bruce, Brid Burruano, Michael R. Hoy, Nicholas R. Paquette
  • Patent number: 6376481
    Abstract: The present invention provides a sterol, stanol or their corresponding acid ester in a form suitable for the manufacture of an oral dosage form. A method for producing the oral dosage form is also provided.
    Type: Grant
    Filed: September 2, 1998
    Date of Patent: April 23, 2002
    Assignee: McNeil-PPC, Inc.
    Inventors: Richard D. Bruce, John D. Higgins, Stephen A. Martellucci
  • Publication number: 20010012521
    Abstract: A method for preparing sterol/stanol and sterol/stanol ester compositions with improved dispersibility is provided by co-melting the sterol/stanol and/or sterol/stanol ester with highly branched hydrocarbons and then grinding the resulting product. A method for preparing the compounds is also disclosed. The ground compound is suitable for formulating into orally administered products suitable for control of blood serum cholesterol.
    Type: Application
    Filed: April 4, 2001
    Publication date: August 9, 2001
    Inventors: Richard D. Bruce, Brid Burruano, Michael R. Hoy, Nicholas R. Paquette
  • Publication number: 20010009677
    Abstract: The present invention provides a stanol material in a form suitable for the manufacture of an oral dosage. A method for producing the stanol material is also provided.
    Type: Application
    Filed: September 2, 1998
    Publication date: July 26, 2001
    Inventors: RICHARD D BRUCE, JOHN D HIGGINS, STEVEN A MARTELLUCCI
  • Patent number: 6242001
    Abstract: A method for preparing sterol/stanol and sterol/stanol ester compositions with improved dispersibility is provided by co-melting the sterol/stanol and/or sterol/stanol ester with highly branched hydrocarbons and then grinding the resulting product. A method for preparing the compounds is also disclosed. The ground compound is suitable for formulating into orally administered products suitable for control of blood serum cholesterol.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: June 5, 2001
    Assignee: McNeil-PPC, Inc.
    Inventors: Richard D. Bruce, Brid Burruano, Michael R. Hoy, Nicholas R. Paquette
  • Patent number: 6123978
    Abstract: The present invention provides a stable foodstuffs which contain a cholesterol lowering amount of a sterol or stanol ester, crystal fat inhibitors and emulsifiers. The foodstuffs, including salad dressings are stable even when refrigerated.
    Type: Grant
    Filed: August 31, 1998
    Date of Patent: September 26, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Clemence K. Dartey, John D. Higgins, III, Richard D. Bruce, Brid T. Burruano
  • Patent number: 6110502
    Abstract: A method for preparing .beta.-sitosterol is disclosed which provides the sterol in a readily consumable form. The method includes the spray drying of the .beta.-sitosterol in a mixed micelle formulation. The product is provided in a convenient form that can be provided to food or drinks or incorporated into solid and suspension dosage forms.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: August 29, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Brid Burruano, Richard D. Bruce, Michael R. Hoy
  • Patent number: 6054144
    Abstract: A method for preparing .beta.-sitosterol, oryzanol, esters of both of these compounds and related compounds are disclosed which provides the sterol in a readily consumable form. The method includes the spray drying of the .beta.-sitosterol in a mixed micelle formulation. The product is provided in a convenient form that can be provided to food or drinks or incorporated into solid and suspension dosage forms.
    Type: Grant
    Filed: November 4, 1998
    Date of Patent: April 25, 2000
    Assignee: McNeil-PPC, Inc.
    Inventors: Brid Burruano, Richard D. Bruce, Michael R. Hoy, John D. Higgins, III
  • Patent number: 5405617
    Abstract: A physicochemically stable pharmaceutical matrix composition is provided comprising: a pharmaceutical active and a water insoluble aliphatic or fatty acid ester, preferably stearyl stearate; a taste mask carrier for pharmaceutical actives comprising a taste masking effective amount of an aliphatic or fatty acid ester; and a method for preparing a pharmaceutical matrix without the use of organic and/or volatile solvents comprising the steps of: melting an aliphatic or fatty acid ester; admixing at least one pharmaceutical active with the molten aliphatic or fatty acid ester; and solidifying the admixture to produce a pharmaceutical matrix composition. The matrix is composed of an aliphatic, or fatty acid, ester that has a low melting point (50.degree.-100.degree. C.) and the melt exhibits: low viscosity, recongeals rapidly when cooled, does not exhibit polymorphism, and has good mold release properties.
    Type: Grant
    Filed: November 7, 1991
    Date of Patent: April 11, 1995
    Assignee: McNeil-PPC, Inc.
    Inventors: Walter G. Gowan, Jr., Richard D. Bruce