Patents by Inventor Richard D. Gless, Jr.

Richard D. Gless, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic noribogaine
    Patent number: 9617274
    Abstract: Synthetic noribogaine preferably free of ibogaine and, optionally, one or more of other naturally occurring Tabernanth iboga alkaloids, is provided.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: April 11, 2017
    Assignee: DEMERX, INC.
    Inventors: Robert M. Moriarty, Richard D. Gless, Jr.
  • Noribogaine salt ansolvates
    Patent number: 9617265
    Abstract: Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can be prepared by slurrying solvated forms, preferably MeOH solvated noribogaine hydrochloride in EtOH/water.
    Type: Grant
    Filed: May 23, 2015
    Date of Patent: April 11, 2017
    Assignee: DEMERX, INC.
    Inventors: Richard D. Gless, Jr., William C. Schinzer
  • STABLE CRYSTALLINE NORIBOGAINE SALT ANSOLVATES
    Publication number: 20170022194
    Abstract: Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can be prepared by slurrying solvated forms, preferably MeOH solvated noribogaine hydrochloride in EtOH/water.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicant: DemeRx, Inc.
    Inventors: Richard D. Gless, JR., William C. Schinzer
  • NORIBOGAINE SALT TABLETS
    Publication number: 20170022193
    Abstract: Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can be prepared by slurrying solvated forms, preferably MeOH solvated noribogaine hydrochloride in EtOH/water.
    Type: Application
    Filed: October 7, 2016
    Publication date: January 26, 2017
    Applicant: DemeRx, Inc.
    Inventors: Richard D. Gless, JR., William C. Schinzer
  • Methods and compositions for preparing noribogaine from voacangine
    Patent number: 9403817
    Abstract: Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: August 2, 2016
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Robert M. Moriarty, Richard D. Gless, Jr.
  • Methods and compositions for preparing and purifying noribogaine
    Patent number: 9394294
    Abstract: Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: July 19, 2016
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr.
  • PHOSPHATE ESTERS OF NORIBOGAINE
    Publication number: 20160115185
    Abstract: Disclosed herein are phosphate esters of noribogaine and dihydronoribogaine, and esters and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the methods of their use, including in the treatment of addiction and/or pain.
    Type: Application
    Filed: May 29, 2015
    Publication date: April 28, 2016
    Applicant: DEMERX, INC.
    Inventors: Richard D. Gless, JR., Robert M. Moriarty
  • NORIBOGAINE SALT ANSOLVATES
    Publication number: 20160108043
    Abstract: Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can be prepared by slurrying solvated forms, preferably MeOH solvated noribogaine hydrochloride in EtOH/water.
    Type: Application
    Filed: May 23, 2015
    Publication date: April 21, 2016
    Applicant: DEMERX, INC.
    Inventors: Richard D. Gless, JR., William C. Schinzer
  • SUBSTITUTED NORIBOGAINE
    Publication number: 20150361080
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Application
    Filed: May 21, 2015
    Publication date: December 17, 2015
    Applicant: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, JR., Robert M. Moriarty
  • Phosphate esters of noribogaine
    Patent number: 9051343
    Abstract: Disclosed herein are phosphate esters of noribogaine and dihydronoribogaine, and esters and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the methods of their use, including in the treatment of addiction and/or pain.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: June 9, 2015
    Assignee: DEMERX, INC.
    Inventors: Richard D. Gless, Jr., Robert M. Moriarty
  • Substituted noribogaine
    Patent number: 9045481
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: June 2, 2015
    Assignee: DEMERX, INC.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr., Robert M. Moriarty
  • Noribogaine salt ansolvates
    Patent number: 9040520
    Abstract: Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can be prepared by slurrying solvated forms, preferably MeOH solvated noribogaine hydrochloride in EtOH/water.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: May 26, 2015
    Assignee: DemeRx, Inc.
    Inventors: Richard D. Gless, Jr., William C. Schinzer
  • METHODS AND COMPOSITIONS FOR PREPARING NORIBOGAINE FROM VOACANGINE
    Publication number: 20150133655
    Abstract: Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: October 14, 2014
    Publication date: May 14, 2015
    Applicant: DEMERX, INC.
    Inventors: Deborah C. Mash, Robert M. Moriarty, Richard D. Gless, JR.
  • Substituted noribogaine
    Patent number: 8940728
    Abstract: This invention relates noribogaine derivatives, compositions and methods of use thereof.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: January 27, 2015
    Assignee: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr., Robert M. Moriarty
  • METHODS AND COMPOSITIONS FOR PREPARING AND PURIFYING NORIBOGAINE
    Publication number: 20140357741
    Abstract: Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: June 6, 2014
    Publication date: December 4, 2014
    Inventors: Deborah C. Mash, Richard D. Gless, JR.
  • Methods and compositions for preparing noribogaine from voacangine
    Patent number: 8859764
    Abstract: Disclosed are methods and compositions for preparing and purifying the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: October 14, 2014
    Assignee: DemeRx, Inc.
    Inventors: Deborah C. Mash, Robert M. Moriarty, Richard D. Gless, Jr.
  • Sulfate esters of noribogaine
    Patent number: 8853201
    Abstract: Disclosed herein are sulfate esters of noribogaine or 9,17 dihydronoribogaine, and pharmaceutically acceptable salts of each thereof, pharmaceutical compositions comprising such compounds, and methods of their use, including in treating addiction and/or pain.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: October 7, 2014
    Assignee: DemeRx, Inc.
    Inventors: Richard D. Gless, Jr., Robert M. Moriarty
  • Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
    Patent number: 8802832
    Abstract: This invention relates generally to compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: August 12, 2014
    Assignee: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr.
  • METHODS AND COMPOSITIONS FOR PREPARING AND PURIFYING NORIBOGAINE
    Publication number: 20140187655
    Abstract: Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
    Type: Application
    Filed: May 10, 2011
    Publication date: July 3, 2014
    Inventors: Deborah C. Mash, Richard D. Gless, JR.
  • Methods and compositions for preparing and purifying noribogaine
    Patent number: 8765737
    Abstract: Disclosed are methods and compositions for purifying the non-addictive alkaloid noribogaine.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: July 1, 2014
    Assignee: DemeRx, Inc.
    Inventors: Deborah C. Mash, Richard D. Gless, Jr.