Patents by Inventor Richard D. Tanaka

Richard D. Tanaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Binding of polyamides to proteins having SH3 or WW domains
    Publication number: 20020002239
    Abstract: Polyamides having heteroaromatic amino acid moieties (especially pyrrole amino acid and/or imidazole amino acid moieties) form complexes with proteins having SH3 or WW domains. As a result of complex formation, the biological activity of such proteins can be inhibited.
    Type: Application
    Filed: December 19, 2000
    Publication date: January 3, 2002
    Inventors: Richard D. Tanaka, Paul J. Simpson
  • Anti-tryptase detection as a diagnostic for inflammatory diseases
    Patent number: 5861264
    Abstract: This invention provides methods of detecting mast cell mediated disease in an individual by detecting the presence in the individual of autoantibodies against mast cell specific proteins, such as tryptase and chymase. Specific mast cell mediated diseases detected by this invention include asthma, rheumatoid arthritis and SLE. The invention also provides a method of detecting autoantibodies against a mast cell specific protein. The method comprises exposing a sample to an sbp member complementary to the autoantibody and detecting the specific binding between the autoantibody and the sbp member. A related aspect of the invention provides methods of treating mast cell mediated diseases by monitoring for the presence of these autoantibodies. Another aspect of the invention relates to a composition comprising an autoantibody against a mast cell specific protein and the mast cell specific protein.
    Type: Grant
    Filed: May 21, 1996
    Date of Patent: January 19, 1999
    Assignee: Axys Pharmaceuticals, Inc.
    Inventors: Kyle C. Elrod, Richard D. Tanaka
  • Nucleic acid encoding human mevalonate kinase
    Patent number: 5349058
    Abstract: Nucleic acid sequences, particularly DNA sequences, coding for all or a portion of human mevalonate kinase, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods for detecting the DNA sequences or the corresponding RNA sequences. The invention also concerns polypeptide molecules comprising all or a portion of human mevalonate kinase.
    Type: Grant
    Filed: February 6, 1990
    Date of Patent: September 20, 1994
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Richard D. Tanaka, Beverly S. Ricci, Stephen T. Mosley