Patents by Inventor Richard E. Ostlund

Richard E. Ostlund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sitostanol formulation with emulsifier to reduce cholesterol absorption and method for preparing and use of same
    Patent number: 6063776
    Abstract: Compositions useful to reduce cholesterol absorption. The compositions may be dosed in capsule or tablet form, or by adding either in liquid or dry powder form to foods and beverages. The compositions are an aqueous based homogeneous micellar mix which is dried to provide a mixture of finely-divided plant sterol, preferably sitostanol and lecithin. The mole ratio of the plant sterol, preferably sitostanol to lecithin, should be within the range of 1:0.1 to 1:10, preferably at least 1:2.
    Type: Grant
    Filed: February 15, 1999
    Date of Patent: May 16, 2000
    Assignee: Washington University
    Inventor: Richard E. Ostlund, Jr.
  • Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same
    Patent number: 5932562
    Abstract: Compositions useful to reduce cholesterol absorption. The compositions may be dosed in capsule or tablet form, or by adding either in liquid or dry powder form to foods and beverages. The compositions are an aqueous based homogeneous micellar mix which is dried to provide a mixture of finely-divided plant sterol, preferably sitostanol and lecithin. The mole ratio of the plant sterol, preferably sitostanol to lecithin, should be within the range of 1:1 to 1:10, preferably at least 1:2.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: August 3, 1999
    Assignee: Washington University
    Inventor: Richard E. Ostlund, Jr.
  • Pinitol and derivatives thereof for the treatment of metabolic disorders
    Patent number: 5827896
    Abstract: Pinitol and derivatives and metabolites thereof are useful in nutritional and medicinal compositions for lowering plasma free fatty acid levels and for treating conditions associated with insulin resistance, such as diabetes mellitus and its chronic complications; obesity; hyperlipidemias and dyslipidemias atherosclerosis; hypertension; cardiovascular disease; AIDS; cancer; wasting/cachexia; sepsis; trauma associated with burns, malnutrition, and stress; aging; lupus and other autoimmune diseases; endocrine disease; hyperuricemia, polycystic ovary syndrome and complications arising from athletic activity.
    Type: Grant
    Filed: March 4, 1996
    Date of Patent: October 27, 1998
    Assignee: Washington University
    Inventors: Richard E. Ostlund, William R. Sherman
  • Pinitol and derivatives thereof for the treatment of metabolic disorders
    Patent number: 5550166
    Abstract: Pinitol and derivatives and metabolites thereof are useful in nutritional and medicinal compositions for treating conditions associated with insulin resistance, such as diabetes mellitus and its chronic complications; obesity; hyperlipidemias and dyslipidemias atherosclerosis; hypertension; cardiovascular disease; AIDS; cancer; wasting/cachexia; sepsis; trauma associated with burns, malnutrition, and stress; aging; lupus and other autoimmune diseases; endocrine disease; hyperuricemia, polycystic ovary syndrome and complications arising from athletic activity or inactivity.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: August 27, 1996
    Inventors: Richard E. Ostlund, William R. Sherman
  • Method for measuring human cholesterol absorption using metabolically stable isotopes
    Patent number: 5432058
    Abstract: This invention is a method for measuring the ability of a human to absorb cholesterol. The method uses two different cholesterol tracers, the first injected into the blood stream and the second ingested by the human subject. After a waiting period a blood sample is taken from the human subject and analyzed to determine percent cholesterol absorption based on the actual amounts of the two naturally occurring, metabolically stable cholesterol tracers in the blood. The method of this invention is useful in identifying human subjects as high cholesterol absorbers and thereafter administering therapeutic agents to the subject that inhibit the absorption of cholesterol.
    Type: Grant
    Filed: September 30, 1992
    Date of Patent: July 11, 1995
    Inventors: Louis G. Lange, III, Richard E. Ostlund, Matthew S. Bosner