Patents by Inventor Richard E. Philips, Jr.

Richard E. Philips, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating cross-linked biological tissues
    Patent number: 6322593
    Abstract: A method for treating biological tissue is provided in which a cross-linked biological tissue containing free aldehyde groups is reacted with a suitable neutralization agent in order to chemically block the aldehyde groups from reactivity toward cellular proteins. Also provided is the cross-linked biological tissue so produced which is substantially free of reactive aldehyde groups and, as a result, exhibits reduced toxicity and improved biocompatibility.
    Type: Grant
    Filed: April 9, 1999
    Date of Patent: November 27, 2001
    Assignee: Sulzer Carbomedics Inc.
    Inventors: Chandrashekhar P. Pathak, Mark A. Moore, Richard E. Philips, Jr.
  • Blocked functional reagants for cross-linking biological tissues
    Patent number: 6177514
    Abstract: A method for cross-linking biological tissue is provided which uses as a cross-linking agent a low molecular weight, substantially monomeric polyfunctional aldehyde formed in situ or just prior to cross-linking. The polyfunctional aldehyde is essentially free of the undesirable heterogeneous polymeric species that result from polyfunctional aldehyde self-reactivity. Also provided is biological tissue that is cross-linked with a substantially monomeric glutaraldehyde.
    Type: Grant
    Filed: April 9, 1999
    Date of Patent: January 23, 2001
    Assignee: Sulzer Carbomedics Inc.
    Inventors: Chandrashekhar P. Pathak, Mark A. Moore, Richard E. Philips, Jr.