Patents by Inventor Richard F. Stockel
Richard F. Stockel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8926997Abstract: A polymeric biocidal salt is prepared from two components. The first component comprises a biocidal anionic or cationic monomeric, dendrimeric or polymeric ion. The second component comprises a dendrimeric or polymeric anion or cation having insignificant biocidal activity and a number average molecular weight of at least about 500. The second component will be cationic in nature when the first component is anionic in nature and anionic in nature when the first component is cationic in nature. The salt is further characterized as partially dissolving when exposed to an aqueous medium, thereby: (a) releasing sufficient biocidal ion to exceed the MIC or MBIC of a target bacteria sought to be controlled; and (b) leaving a reservoir of undissolved salt capable of being further dissolved and releasing additional biocidal ion as the biocidal ion is consumed or is otherwise removed from the environment encompassing the target bacteria.Type: GrantFiled: April 5, 2010Date of Patent: January 6, 2015Inventors: Richard F. Stockel, Anthony J. Sawyer
-
Publication number: 20140349903Abstract: A method for cleaning, benefiting, or deodorizing skin or hair utilizing a body wash, skin cleaner, soap, shampoo or deodorizer formulation containing a controlled release skin benefit or deodorizing salt, a hydrophilic moisturizing polymer and surfactants is described. The method imparts benefits or deodorizing agents to the skin or hair and maintains effective levels for an extended period.Type: ApplicationFiled: August 6, 2014Publication date: November 27, 2014Inventors: Anthony E. WINSTON, Richard F. STOCKEL, Anthony Joseph SAWYER
-
Publication number: 20140303101Abstract: This invention pertains to dental care compositions with antimicrobial benefits. In particular, the invention provides for compositions of oral tissue-adherent salts that release biocidal ions on a controlled release basis and thereby provide and maintain an essentially uniform concentration of biocidal ions above the MBC or MIC of the target bacteria at the site of application in the mouth for an extended period of time. The compositions are useful for treating or preventing oral diseases resulting from bacteria, fungal or yeast infections, such as caries, gingivitis, periodontal disease and candidiasis.Type: ApplicationFiled: June 25, 2014Publication date: October 9, 2014Inventors: Anthony Errol Winston, Richard F. Stockel, Anthony Joseph Sawyer
-
Publication number: 20140303100Abstract: This invention pertains to dental care compositions with antimicrobial benefits. In particular, the invention provides for compositions of oral tissue-adherent salts that release biocidal ions on a controlled release basis and thereby provide and maintain an essentially uniform concentration of biocidal ions above the MBC or MIC of the target bacteria at the site of application in the mouth for an extended period of time. The compositions are useful for treating or preventing oral diseases resulting from bacteria, fungal or yeast infections, such as caries, gingivitis, periodontal disease and candidiasis.Type: ApplicationFiled: June 25, 2014Publication date: October 9, 2014Inventors: Anthony Errol Winston, Richard F. Stockel, Anthony Joseph Sawyer
-
Patent number: 8834857Abstract: A method for cleaning, benefiting, or deodorizing skin or hair utilizing a body wash, skin cleaner, soap, shampoo or deodorizer formulation containing a controlled release skin benefit or deodorizing salt, a hydrophilic moisturizing polymer and surfactants is described. The method imparts benefits or deodorizing agents to the skin or hair and maintains effective levels for an extended period.Type: GrantFiled: January 18, 2012Date of Patent: September 16, 2014Assignee: Nevada Naturals Inc.Inventors: Anthony E. Winston, Richard F. Stockel, Anthony Joseph Sawyer
-
Patent number: 8795638Abstract: This invention pertains to dental care compositions with antimicrobial benefits. In particular, the invention provides for compositions of oral tissue-adherent salts that release biocidal ions on a controlled release basis and thereby provide and maintain an essentially uniform concentration of biocidal ions above the MBC or MIC of the target bacteria at the site of application in the mouth for an extended period of time. The compositions are useful for treating or preventing oral diseases resulting from bacteria, fungal or yeast infections, such as caries, gingivitis, periodontal disease and candidiasis.Type: GrantFiled: October 6, 2011Date of Patent: August 5, 2014Assignee: Nevada Naturals Inc.Inventors: Anthony Errol Winston, Richard F. Stockel, Anthony Joseph Sawyer
-
Publication number: 20140154940Abstract: A controlled release biocidal salt of a first component comprises a cation of a N?—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and a second component comprising an anion of a monomeric anionic molecule having insignificant biocidal activity. The salt is characterized such that when the salt is exposed to an aqueous medium, the salt partially dissolves thereby releasing biocidal ions in an amount sufficient to exceed the MIC or MBC of a target bacteria being controlled, and further characterized as leaving a residual reservoir of undissolved salt capable of releasing more biocidal ions as the salt is consumed or otherwise removed from the environment encompassing the target bacteria. The preferred cationic biocidal molecule comprises N?-lauroyl-L-arginine ethyl ester (“LAE”).Type: ApplicationFiled: February 10, 2014Publication date: June 5, 2014Applicant: Nevada Naturals Inc.Inventors: Anthony J. Sawyer, Richard F. Stockel
-
Patent number: 8734879Abstract: This invention discloses a method of preservation of a food product comprising the step of adding 1) a first component comprising between 10 ppm and 1% of a biocidal salt of N?-(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule with an anionic counterion, and 2) a second component comprising from 10 ppm to 1% by weight an acyl monoglyceride, directly to a food product. The preferred cationic biocidal molecule comprises N?-lauroyl-L-arginine ethyl ester (“LAE”). The invention also discloses the method of preservation of a food product using salts of a N?-(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and an anionic counterion with or without a monoglyceride of a fatty acid, whereby the packaging film is compounded with the salts and the optional monoglyceride of a fatty acid.Type: GrantFiled: June 28, 2013Date of Patent: May 27, 2014Assignee: Nevada Naturals Inc.Inventors: Anthony J. Sawyer, Richard F. Stockel
-
Publication number: 20130289111Abstract: This invention discloses a method of preservation of a food product comprising the step of adding 1) a first component comprising between 10 ppm and 1% of a biocidal salt of N?-(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule with an anionic counterion, and 2) a second component comprising from 10 ppm to 1% by weight an acyl monoglyceride, directly to a food product. The preferred cationic biocidal molecule comprises N?-lauroyl-L-arginine ethyl ester (“LAE”). The invention also discloses the method of preservation of a food product using salts of a N?-(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and an anionic counterion with or without a monoglyceride of a fatty acid, whereby the packaging film is compounded with the salts and the optional monoglyceride of a fatty acid.Type: ApplicationFiled: June 28, 2013Publication date: October 31, 2013Inventors: Anthony J. Sawyer, Richard F. Stockel
-
Publication number: 20130231389Abstract: A composition comprising a polymeric material and a preservative combination of 1) a preservative component selected from the salts of N?—(C1-C18) acyl di-basic amino acid (C1-C18) alkyl ester; 2) a second component selected from a food-safe solvent, food-safe nonionic surfactant or mixtures thereof; and optionally; 3) a third component consisting of an acyl mono-glyceride, wherein the preservative is diffusible from the polymeric material.Type: ApplicationFiled: April 15, 2013Publication date: September 5, 2013Applicant: NEVADA NATURALS, INC.Inventors: Anthony J. Sawyer, Richard F. Stockel
-
Publication number: 20130136832Abstract: This invention discloses a method of preservation of a food product comprising the step of adding 1) a first component comprising between 10 ppm and 1% of a biocidal salt of N?—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule with an anionic counterion, and 2) a second component comprising from 10 ppm to 1% by weight an acyl monoglyceride, directly to a food product. The preferred cationic biocidal molecule comprises N?-lauroyl-L-arginine ethyl ester (“LAE”). The invention also discloses the method of preservation of a food product using salts of a N?—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and an anionic counterion with or without a monoglyceride of a fatty acid, whereby the packaging film is compounded with the salts and the optional monoglyceride of a fatty acid.Type: ApplicationFiled: April 4, 2011Publication date: May 30, 2013Inventors: Anthony Joseph Sawyer, Richard F. Stockel
-
Publication number: 20120328544Abstract: A dermatological composition for application to the skin or nails comprises a salt of a cation and an anion. The cation is derived from a monomeric or polymeric molecule that will generate an amidine moiety, a guanidine moiety or a biguanide moiety. The anion is derived from a monomeric or polymeric molecule that will generate a carboxylic acid moiety. The composition may be prepared by a metathesis or acid-base reaction.Type: ApplicationFiled: August 31, 2012Publication date: December 27, 2012Applicant: Nevada Naturals, Inc.Inventors: Richard F. Stockel, Anthony J. Sawyer, Anthony E. Winston
-
Publication number: 20120225942Abstract: Synergistic antimicrobial compositions are provided by combining effective amounts of N?-long chain alkanoyl di basic amino acid alkyl ester salts with glycerol monofatty acid esters resulting more effective anti-microbials and food preservatives.Type: ApplicationFiled: May 7, 2012Publication date: September 6, 2012Applicant: Nevada Naturals, Inc.Inventors: Richard F. Stockel, Anthony J. Sawyer
-
Publication number: 20120148530Abstract: An inexpensive, easily available, and convenient method of treating or preventing a virus infection is provided. The present invention relates to a method for the treatment or prevention of virus infections using polybiguanide-based compounds administering a therapeutically effective amount of a compound or a pharmaceutically acceptable salt thereof The invention relies on the unique biochemical reaction in which polybiguanide-based compounds interfere with the spread of virus within or between organisms. The compositions and formulations described in the present invention are effective means to reduce the infectivity of the human immunodeficiency virus type 1 (HIV-1), and human herpes simplex viruses, and also to kill the causative organisms of many other sexually transmitted diseases (STDs).Type: ApplicationFiled: June 21, 2010Publication date: June 14, 2012Applicant: Novaflux Biosciences, Inc.Inventors: Mohammed E. Labib, Richard F. Stockel
-
Patent number: 8193244Abstract: The combination of N?-long chain alkanoyl di basic amino acid alkyl ester salts with glycerol monofatty acid esters results in biocidal synergy and the extension of cidal activity of the di basic amino acid derivative for a variety of antimicrobial applications like oral care, wound care, dermatological care, animal care, and cosmetic applications. N?-C8-C14-long chain alkanoyl-L-arginine alkyl (C1-C4 short chain) ester salts with glycerol monofatty acid esters (C8-C14) are very effective as antimicrobial agents for hospital use particularly as a coating for surgical drapes, covers, walls, trays, table tops, gurneys, or the like. Other uses include the treatment of HSV-1 (fever sore) and as a microbicide when using the combination of the di basic amino acid ester derivative with glycerol monofatty acid esters for preventing HIV and STD's.Type: GrantFiled: May 28, 2009Date of Patent: June 5, 2012Assignee: Nevada Naturals, Inc.Inventors: Richard F. Stockel, Anthony Joseph Sawyer
-
Publication number: 20110177229Abstract: A food preservative composition comprising a N?-alkyl-dibasic amino acid alkyl ester salt in combination with liquid smoke. Preferably, the food preservative composition comprises a N?-alkyl-dibasic amino acid alkyl ester halide salt in combination with liquid smoke. The particularly preferred composition comprises N?-lauroyl-L-arginine ethyl ester hydrochloride in combination with clarified liquid smoke. The composition preferably also contains a surfactant and/or a solubilizer and/or a non-toxic GRAS solvent.Type: ApplicationFiled: March 28, 2011Publication date: July 21, 2011Inventors: Gil J. Bakal, Richard F. Stockel, Brandon D. Baer, Bruce A. Nascimbeni
-
Patent number: 7772284Abstract: An inexpensive, easily available, and convenient method of treating or preventing a virus infection is provided. The present invention relates to a method for the treatment or prevention of virus infections using polybiguanide-based compounds administering a therapeutically effective amount of a compound or a pharmaceutically acceptable salt thereof. The invention relies on the unique biochemical reaction in which polybiguanide-based compounds interfere with the spread of virus within or between organisms. The compositions and formulations described in the present invention are effective means to reduce the infectivity of the human immunodeficiency virus type 1 (HIV-1), and human herpes simplex viruses, and also to kill the causative organisms of many other sexually transmitted diseases (STDs).Type: GrantFiled: August 27, 2003Date of Patent: August 10, 2010Inventors: Mohamed E. Labib, Richard F. Stockel
-
Publication number: 20100173993Abstract: A controlled release biocidal salt of a first component comprises a cation of a N?—(C1-C22)alkanoyl di-basic amino acid alkyl(C1-C22)ester cationic biocidal molecule and a second component comprising an anion of a monomeric anionic molecule having insignificant biocidal activity. The salt is characterized such that when the salt is exposed to an aqueous medium, the salt partially dissolves thereby releasing biocidal ions in an amount sufficient to exceed the MIC or MBC of a target bacteria being controlled, and further characterized as leaving a residual reservoir of undissolved salt capable of releasing more biocidal ions as the salt is consumed or otherwise removed from the environment encompassing the target bacteria. The preferred cationic biocidal molecule comprises N?-lauroyl-L-arginine ethyl ester (“LAE”).Type: ApplicationFiled: February 4, 2010Publication date: July 8, 2010Inventors: Anthony J. Sawyer, Richard F. Stockel
-
Publication number: 20100056628Abstract: Green and naturally derived biocides such as N?—(C1-C22) alkanoyl di basic amino acid alkyl (C1 to C22) ester salt cationic molecules can be combined with an anionic molecule not generally considered as having significant biocidal activity to provide antimicrobial, antibacterial, and/or antifungal properties with multifunctional benefits including preservative or self-preserving activity.Type: ApplicationFiled: October 19, 2009Publication date: March 4, 2010Inventors: Richard F. Stockel, Anthony Joseph Sawyer
-
Publication number: 20090318557Abstract: A dermatological composition comprising a salt of a cation and an anion. The cation is derived from a monomeric or polymeric molecule that will generate an amidine moieity, a guanidine moieity or a biguanide moieity. The anion is derived from a monomeric or polymeric molecule that will generate a carboxylic acid moieity. The composition may be prepared by a metathesis or acid-base reaction.Type: ApplicationFiled: August 27, 2009Publication date: December 24, 2009Inventor: Richard F. Stockel