Abstract: Provided is 4-methylumbelliferone, derivatives and salts thereof, or a composition comprising same for use in the treatment of a condition of the nervous system in a subject. Preferably, the condition is one associated with a scar, such as a glial scar. Typically, the condition of the nervous system is selected from the group comprising conditions caused by trauma, injury, infection, degeneration, structural defects, tumours, blood flow disruption. The neural and other lesions are made permeable and repairable.

Abstract: An electrical capacitance tomography (ECT) system for determining, in use, a distribution of a fluid in a vessel is described which comprises a plurality of electrodes disposed in or about the vessel; and a processor operably coupled to the electrodes and being configured to determine from outputs therefrom, by an ECT method, the distribution of fluid in the vessel wherein at least some of the plurality of electrodes are mesh electrodes. Aspects of the invention provide such an apparatus and methods of carrying out tomography including such electrodes and methods of constructing a system. The electrodes are more robust and lighter than electrodes previously used enabling the use in space applications.

Abstract: Disclosed is a wireless zoning system and devices for an HVAC system. Included is one or more light switch thermostat(s) designed to fit into a standard light switch box, a wireless zone control gateway, an HVAC control module, and one or more wireless damper sensors. The light switch thermostats include one or more mini pcb with a sensor mounted on it to monitor for example occupancy, humidity, and other VOC. The light switch thermostat also includes a vent opening on a switch plate located near the mini pcb with sensor. The wireless damper sensor is designed with RJ11 jacks to minimize cabling costs. The disclosed system can be designed for air or water HVAC systems.

Abstract: This invention relates to compounds of formula (I). The compounds of formula (I) are modulators of Factor XII, specifically Factor XIIa. The compounds are inhibitors of Factor XIIa and may be useful as anticoagulants. The compounds of formula (I) may be used in methods of treatment (or prevention) of blood disorders related to bleeding or coagulation.

Abstract: An apparatus includes a handle having a handle fluid input, a handle fluid output, a first handle electrical contact, a second handle electrical contact, a first handle air passage, and a second handle air passage. The apparatus also includes a shaft having a shaft fluid input, a shaft fluid output, a first shaft electrical contact, a second shaft electrical contact, a first shaft air passage, a second shaft air passage, and a first shaft coupling including the shaft fluid input, the first shaft electrical contact and the first shaft air passage. The first shaft coupling is configured to mate with the handle to connect the shaft fluid input with the handle fluid output, connect the first shaft electrical contact with the second handle electrical contact with the second handle electrical contact, and connect the first shaft air passage with the second handle air passage.

Abstract: An apparatus includes a handle having a handle fluid input, a handle fluid output, a first handle electrical contact, a second handle electrical contact, a first handle air passage, and a second handle air passage. The apparatus also includes a shaft having a shaft fluid input, a shaft fluid output, a first shaft electrical contact, a second shaft electrical contact, a first shaft air passage, a second shaft air passage, and a first shaft coupling including the shaft fluid input, the first shaft electrical contact and the first shaft air passage. The first shaft coupling is configured to mate with the handle to connect the shaft fluid input with the handle fluid output, connect the first shaft electrical contact with the second handle electrical contact with the second handle electrical contact, and connect the first shaft air passage with the second handle air passage.

Abstract: An apparatus comprises a body, a first tank, a second tank, a vacuum motor, a fluid pump, and a controller. The body comprises a handle and an accessory connection receptacle comprising a fluid output and an electrical contact. The first tank comprises a first vessel configured to accommodate a fluid. The second tank comprises a second vessel separated from the first vessel. The controller is configured to activate the fluid pump to cause fluid contained in the first tank to be supplied to the fluid output, and to activate the vacuum motor to draw one or more of air, debris, a liquid or a portion of the fluid into the second tank. The accessory connection receptacle is configured to accommodate a correspondingly shaped accessory connector configured to mate with the accessory connection receptacle and be communicatively coupled with the fluid output and with the electrical contact.

Abstract: In order to measure a fluid flow or flow conditions of a fluid flow through an apparatus, electrodes are provided across which capacitance values are determined. The capacitances are used in conjunction with a predetermined model to determine a revised model for the system. If the modelled to be satisfactory, then the values representative of the flow conditions are output. If it is not, then the model is tuned to reduce the error. A novel arrangement of electrodes is also provided along with apparatus embodying the method. The invention also provides a way of determining fluid properties, for example, density, volume present contained within a vessel or tank whether flowing or stationary.

Abstract: An apparatus includes a body, a first tank and a second tank. The body includes a first fluid coupling and a first air passage. The first tank includes a first vessel configured to accommodate a fluid and a second fluid coupling communicatively coupled with the first fluid coupling. The second tank includes a second vessel separated from the first vessel and a second air passage communicatively coupled with the first air passage. The apparatus also includes a tank base over the body. The tank base includes a first tank seat configured to accommodate the first tank and a second tank seat configured to accommodate the second tank. The tank base is configured to be separated from the body with at least one of the first tank in the first tank seat or the second tank in the second tank seat.

Abstract: An apparatus includes a body, a first tank and a second tank. The body includes a first fluid coupling and a first air passage. The first tank includes a first vessel configured to accommodate a fluid and a second fluid coupling communicatively coupled with the first fluid coupling. The second tank includes a second vessel separated from the first vessel and a second air passage communicatively coupled with the first air passage. The apparatus also includes a tank base over the body. The tank base includes a first tank seat configured to accommodate the first tank and a second tank seat configured to accommodate the second tank. The tank base is configured to be separated from the body with at least one of the first tank in the first tank seat or the second tank in the second tank seat.

Abstract: In order to measure a fluid flow or flow conditions of a fluid flow through an apparatus, electrodes are provided across which capacitance values are determined. The capacitances are used in conjunction with a predetermined model to determine a revised model for the system. If the modelled to be satisfactory, then the values representative of the flow conditions are output. If it is not, then the model is tuned to reduce the error. A novel arrangement of electrodes is also provided along with apparatus embodying the method. The invention also provides a way of determining fluid properties, for example, density, volume present contained within a vessel or tank whether flowing or stationary.