Patents by Inventor Richard G. Ham

Richard G. Ham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human k-casein
    Patent number: 5391497
    Abstract: A cDNA sequence encoding human .kappa.-casein.
    Type: Grant
    Filed: October 13, 1992
    Date of Patent: February 21, 1995
    Assignee: University of Colorado Foundation, Inc.
    Inventors: Ravi S. Menon, Kathleen F. Jeffers, Ying-Fon Chang, Richard G. Ham
  • Media for normal human muscle satellite cells
    Patent number: 5324656
    Abstract: An improved basal nutrient medium MCDB 120 for the clonal growth of human muscle satellite cells (HMSC) is described. In addition, serum-free supplements for the clonal growth of HMSC containing serum albumin, dexamethasone, fetuin fraction mitogen, epidermal growth factor and insulin are described. Combination of MCDB 120 and the serum-free supplement results in a serum-free medium for growth of HMSC, which can be transplanted to muscles of patients afflicted with muscle degenerative diseases such as muscular dystrophy. The serum-free supplement can also be used with other basal nutrient media such as MCDB 131M for growth of HMSC. Addition of 5% dialyzed fetal bovine serum to the serum-free media described results in semi-defined media which allows significantly improved growth of HMSC.
    Type: Grant
    Filed: August 12, 1992
    Date of Patent: June 28, 1994
    Assignee: University of Colorado Foundation, Inc.
    Inventors: Richard G. Ham, Judith A. St. Clair, Zetan Nie
  • Media for normal human muscle satellite cells
    Patent number: 5143842
    Abstract: An improved basal nutrient medium MCDB 120 for the clonal growth of human muscle satellite cells (HMSC) is described. In addition, a serum-free supplement for the clonal growth of HMSC containing serum albumin, dexamethasone, fetuin epidermal growth factor and insulin. Combination of MCDB 120 and the serum-free supplement results in a serum-free medium for growth of HMSC. The serum-free supplement can also be used with other basal nutrient media such as MCDB 131M for growth of HMSC. Addition of 5% dialyzed fetal bovine serum to the serum-free media described results in semi-defined media which allows significantly improved growth of HMSC.
    Type: Grant
    Filed: November 1, 1988
    Date of Patent: September 1, 1992
    Assignee: The University of Colorado Foundation, Inc.
    Inventors: Richard G. Ham, Judith A. St. Clair
  • Process and defined medium for growth of human epidermal keratinocyte cells
    Patent number: 4940666
    Abstract: Disclosed are novel methods and materials for generating in vitro cultured populations of human epidermal keratinocyte cells having a characteristic colony-forming efficiency of greater than 20%. Novel media preparations and procedures are disclosed that permit isolation, serum-free primary culture and serum-free serial subculture of human epidermal keratinocytes. Also disclosed are procedures and products employing keratinocyte cells grown in serum-free conditions for medical application. i.e., skin grafting.
    Type: Grant
    Filed: December 9, 1986
    Date of Patent: July 10, 1990
    Assignee: University Patents, Inc.
    Inventors: Stephen T. Boyce, Richard G. Ham
  • Process and defined medium for growth of human epidermal keratinocyte cells
    Patent number: 4673649
    Abstract: Disclosed are novel methods and materials for generating in vitro cultured populations of human epidermal keratinocyte cells having a characteristic colony-forming efficiency of greater than 20%. Novel media preparations and procedures are disclosed that permit isolation, serum-free primary culture and serum-free serial subculture of human epidermal keratinocytes. Also disclosed are procedures and products employing keratinocyte cells grown in serum-free conditions for medical application, i.e., skin grafting.
    Type: Grant
    Filed: July 15, 1983
    Date of Patent: June 16, 1987
    Assignee: University Patents, Inc.
    Inventors: Steven T. Boyce, Richard G. Ham