Abstract: An ion source able to ionize both liquid and gaseous vapors from interfaced liquid separation techniques and a solids/liquid atmospheric pressure (AP) probe. The liquid effluents are ionized by electrospray ionization, photoionization or atmospheric pressure chemical ionization and the vapors released from a probe device placed in a heated gas stream in the AP source are ionized by a corona or Townsend electrical discharge or photoionization. The source has the ability to ionize compounds from both liquid and solid sources, which facilitates ionization of volatile and semivolatile compounds by applying heat from a gas stream as well as highly non-volatile compounds infused by electrospray or separated by liquid chromatography or capillary electrophoresis.

Abstract: An ion source able to ionize both liquid and gaseous vapors from interfaced liquid separation techniques and a solids/liquid atmospheric pressure (AP) probe. The liquid effluents are ionized by electrospray ionization, photoionization or atmospheric pressure chemical ionization and the vapors released from a probe device placed in a heated gas stream in the AP source are ionized by a corona or Townsend electrical discharge or photoionization. The source has the ability to ionize compounds from both liquid and solid sources, which facilitates ionization of volatile and semivolatile compounds by applying heat from a gas stream as well as highly non-volatile compounds infused by electrospray or separated by liquid chromatography or capillary electrophoresis.

Abstract: An atmospheric pressure (AP) mass spectrometry ion source able to ionize analytes in liquid effluents from interfaced liquid separation techniques and from individual containers, as in microtiter plates, by direct introduction of the analyte into the ion source using a moving ribbon, wire, or belt with vaporization of the analyte and subsequent ionization using an electric discharge or photoionization. The AP source may also incorporate atmospheric pressure chemical ionization (APCI), photoionization (APPI) and/or electrospray ionization (ESI), techniques that are commercially available. The source facilitates ionization of volatile and semivolatile compounds by applying heat from a gas stream to vaporize analyte entering the ionization region on a moving transport device. Solvent removal prior to sample entering the ionization region enables ionization of a wider range of compounds than liquid introduction APCI or APPI.