Abstract: A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.

Abstract: A web crawler for downloading and analyzing the contents of a merchant's website. The web crawler may analyze the products advertised and determine whether a service plans is properly associated. The crawler may also analyze the placement of the service plan on the website, and store the information in a database. A dynamic mapper is also provided which can determine what service plan should be associated with a particular product. The dynamic mapper may also suggest what type of control to use for a particular customer. A webserver containing software for updating a webpage is also disclosed. A process for updating a webpage is also disclosed.

Abstract: Methods, systems, and articles of manufacture consistent with the present invention provide a system and method for sharing and recording information on a wired or wireless computer network during synchronous and asynchronous sessions. A software program uses computers to enhance the collaboration, teaching, learning, presentation, and sharing of information and to record multi-media events for later playback and interaction with these events. Collaboration is enhanced by using features that allow broadcasting presentations, sharing, editing and replying to documents, taking notes, viewing participant information, creating and responding to polling questions, asking and answering questions and providing feedback on the pace and difficulty of the session. In particular, users may add notes during the recording of a multi-media presentation that are synchronized timewise with the presentation. When the presentation is played back, the notes are displayed at the correct time and space in which they were added.

Abstract: Systems and methods for transmitting signals concerning the location of an emergency vehicle to other cars traveling in the vicinity of the emergency vehicle alert the other vehicles to the presence of the emergency vehicle. A transmitter unit which is desirably automatically switched on whenever the flashing lights and sirens of the emergency vehicle are activated. transmits a signal preferably only within a limited range adjacent or near the emergency vehicle. The transmitted signal preferably identifies the present location and direction of the emergency vehicle. The location and direction information of the emergency vehicle is preferably provided by GPS data generated by a GPS system associated with the emergency vehicle. Automobiles and other vehicles are outfitted with receivers for receiving the signals transmitted by emergency vehicles as described above.

Abstract: A method and system for providing a magnetoresistive sensor is disclosed. The method and system include providing a first pinned layer, providing a first spacer layer above the first pinned layer, and providing a free layer above the first spacer layer. The method and system further include providing a second spacer layer above the free layer and providing a second pinned layer above the second spacer layer. The first pinned layer includes a first magnetic layer and a second magnetic layer separated by a first nonmagnetic layer. The first magnetic layer is antiferromagnetically coupled with the second magnetic layer. The second pinned layer includes a third magnetic layer and a fourth magnetic layer separated by a second nonmagnetic layer. The third magnetic layer is antiferromagnetically coupled with the fourth magnetic layer. The first pinned layer and the second pinned layer are pinned by a current carried by the magnetoresistive head during use.