Patents by Inventor Richard H. Mathews
Richard H. Mathews has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9494579Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: GrantFiled: September 9, 2014Date of Patent: November 15, 2016Assignee: Massachusetts Institute of TechnologyInventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Publication number: 20150050723Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: ApplicationFiled: September 9, 2014Publication date: February 19, 2015Inventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Patent number: 8835127Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: GrantFiled: October 6, 2011Date of Patent: September 16, 2014Assignee: Massachusetts Institute of TechnologyInventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Publication number: 20120135404Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: ApplicationFiled: October 6, 2011Publication date: May 31, 2012Applicant: Massachusetts Institute of TechnologyInventors: Eric. D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Patent number: 8067184Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: GrantFiled: July 3, 2008Date of Patent: November 29, 2011Assignee: Massachusetts Institute of TechnologyInventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Publication number: 20100041031Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: ApplicationFiled: July 3, 2008Publication date: February 18, 2010Inventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Patent number: 7422860Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: GrantFiled: December 1, 2004Date of Patent: September 9, 2008Assignee: Massachusetts Institute of TechnologyInventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Patent number: 7417539Abstract: A baby monitor system includes a transmitter unit that has a first receiver to receive baby sounds, a transmitter to transmit a signal corresponding to the baby sounds, and a transmitter housing to house the first receiver and the transmitter. The transmitter housing includes a faceplate connector. The baby monitor system also includes a receiver unit having a second receiver to receive the signal transmitted by the transmitter unit. The baby monitor system further includes a plurality of transmitter faceplates that can be interchangeably connected to the faceplate connector of the transmitter housing.Type: GrantFiled: May 11, 2005Date of Patent: August 26, 2008Assignee: Graco Children's Products Inc.Inventors: Richard H. Mathews, Jeffrey Swan, Thomas Pollack
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Publication number: 20080166705Abstract: The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.Type: ApplicationFiled: December 1, 2004Publication date: July 10, 2008Applicant: Massachusetts Institute of TechnologyInventors: Eric D. Schwoebel, James D. Harper, Martha S. Petrovick, Frances E. Nargi, Todd H. Rider, Kristine E. Hogan, Richard H. Mathews, Joseph Lacirignola, Mark Hennessy, Trina R. Vian, Rose M. Joseph, Raymond S. Uttaro, Shaun Berry, Bernadette Johnson, Mark A. Hollis
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Patent number: 6961968Abstract: A bassinet and changing table assembly includes a frame, a changing table mounted to the frame, and a bassinet releasably mounted to the changing table and/or the frame so that the bassinet is positioned over the changing table. Hence, the diaper changing activity is separated from the child sleeping area.Type: GrantFiled: March 25, 2004Date of Patent: November 8, 2005Assignee: Graco Children's Products Inc.Inventors: Joshua E. Clapper, Cindy Berkey, Richard H. Mathews
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Patent number: 5846708Abstract: A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular structure or structures. A signal is applied to the test sites and certain electrical, mechanical and/or optical properties of the test sites are detected to determine which probes have bonded to an associated target molecular structure.Type: GrantFiled: April 23, 1992Date of Patent: December 8, 1998Assignee: Massachusetts Institiute of TechnologyInventors: Mark A. Hollis, Daniel J. Ehrlich, R. Allen Murphy, Bernard B. Kosicki, Dennis D. Rathman, Richard H. Mathews, Barry E. Burke, Mitch D. Eggers, Michael E. Hogan, Rajender Singh Varma
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Patent number: 5653939Abstract: A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular structure or structures. A signal is applied to the test sites and certain electrical, mechanical and/or optical properties of the test sites are detected to determine which probes have bonded to an associated target molecular structure.Type: GrantFiled: August 7, 1995Date of Patent: August 5, 1997Assignees: Massachusetts Institute of Technology, Houston Advanced Research Center, Baylor College of MedicineInventors: Mark A. Hollis, Daniel J. Ehrlich, R. Allen Murphy, Bernard B. Kosicki, Dennis D. Rathman, Chang-Lee Chen, Richard H. Mathews, Barry E. Burke, Mitch D. Eggers, Michael E. Hogan, Rajender Singh Varma
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Patent number: 4234883Abstract: Time-correlation apparatus for collecting correlation data when the noise level is low and inhibiting the collection of correlation data when the noise level is high without losing valid correlation data which has already been obtained. An incoming signal is checked for data pulses during each correlation measurement pulse of a synchronizing signal. The correlation measurement pulses are counted by a first counter, and the coincidences of data pulses and correlation measurement pulses are counted by a second counter. A noise monitor samples the incoming signals 100 times during each of a continuous series of noise analysis periods and counts the number of times the signal (assumed to be noise) exceeds a predetermined threshold. A high noise signal is generated if the threshold is exceeded 30 or more times, and a low noise signal if it is exceeded less than 30 times.Type: GrantFiled: September 26, 1974Date of Patent: November 18, 1980Assignee: GTE Sylvania IncorporatedInventors: Oscar J. Kaelin, Richard H. Mathews