Abstract: The present disclosure generally relates to binding agents that are capable of targeting tumor cells and/or immune cells. The binding agents of the present disclosure comprise one or more antigen binding domains of heavy chain antibodies (HcAb) which are capable of binding to DR2, to PD-1 and/or to CD47. The binding agents of the present disclosure may be in the form of monomers or multimers and may be monospecific or multispecific.

Abstract: Digital image capture and processing engine of modular design and employing an optical waveguide structure for collecting and guiding LED-based illumination during object illumination and imaging operations. The digital image capture and processing engine also includes apparatus for automatically controlling the duration of illumination produced from LED illumination arrays during object illumination and imaging operations. Such automatic illumination control involves measuring the amount of illumination to which the object be imaged has been exposed, and controlling the duration of illumination produced from the LED illumination arrays based on such measurements during each object illumination and imaging operation. By virtue of the present invention, the digital image capture and processing engine ensures the reliable formation and detection of high quality images in diverse application environments in the digital image capture and processing engine can be used.

Abstract: A digital image capture and processing system having a housing with a light transmission window, and an illumination subsystem including an illumination board disposed adjacent the light transmission window, configured substantially within a plane, and having a central aperture mounted adjacent the imaging window. The illumination board supports an array of illumination sources mounted around at least portion of the central aperture, for producing and a field of illumination within the FOV of its image formation and detection subsystem during object illumination and imaging operations. A FOV folding mirror is mounted within the housing and beneath the illumination board, and folds the path of the FOV beneath the light transmission aperture and directs and projects the FOV out through the central aperture. Also, an automatic illumination control subsystem is provided for controlling the array of illumination sources during object illumination and imaging operations.

Abstract: An automatic digital video-imaging based code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video-imaging based code symbol reading techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing the versatility required to accommodate the different ways in which operators present objects for code symbol reading at POS environments.

Abstract: An automatic digital video imaging based code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video imaging based code symbol reading techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing the versatility required to accommodate the different ways in which operators present objects for code symbol reading at POS environments.

Abstract: An automatic automatically-triggered digital video imaging based code symbol reading system for use in point of sale (POS) environments, employing an adaptive control process involving the real-time analysis of the exposure quality of captured frames of digital image data and the real-time reconfiguration of system control parameters (SCPs) based on the results of such exposure quality analysis. By virtue of the present invention, the system enables the reliable reading of code symbols graphically represented in digital images, under demanding point-of-sale lighting conditions and other challenging environments.

Abstract: An automatic code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video image capturing and processing techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing versatility required to accommodate the different ways in which human operators present objects for code symbol reading at POS environments.

Abstract: An automatic digital-imaging based code symbol reading system supporting a presentation mode of system operation, automatic object direction detection and illumination control, and video image capture and processing techniques. By virtue of the present invention, the automatic digital-imaging based code symbol reading system ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments.

Abstract: A digital image capture and processing system employing automated real-time analysis of digital image exposure quality to automatically reconfigure system control parameters, and dynamically control illumination and imaging operations within the digital image capture and processing system.

Abstract: A digital image capture and processing system having a housing with a light transmission window, and an illumination subsystem including an illumination board disposed adjacent the light transmission window, configured substantially within a plane, and having a central aperture mounted adjacent the imaging window. The illumination board supports an array of illumination sources mounted around at least portion of the central aperture, for producing and a field of illumination within the FOV of its image formation and detection subsystem during object illumination and imaging operations. A FOV folding mirror is mounted within the housing and beneath the illumination board, and folds the path of the FOV beneath the light transmission aperture and directs and projects the FOV out through the central aperture. Also, an automatic illumination control subsystem is provided for controlling the array of illumination sources during object illumination and imaging operations.

Abstract: An automatic digital imaging-based code symbol reading system supporting a presentation-type mode of system operation, a multi-tier modular software architecture, automatic illumination control and video image capture and processing techniques. By virtue of the present invention, the automatic digital imaging-based code symbol reading system ensures the reliable reading of 1D and/or 2D code symbols graphically represented in digital images captured in demanding point-of-sale and other environments.

Abstract: An automatic digital-imaging based code symbol reading system supporting pass-through and presentation modes of system operation, automatic object direction detection and illumination control, and video image capture and processing techniques. By virtue of the present invention, the automatic digital-imaging based code symbol reading system ensures the reliable reading of code symbols graphically represented in digital images in high-throughput point-of-sale and other environments.

Abstract: An automatic digital-imaging based code symbol reading system supporting pass-through and presentation modes of system operation, automatic object direction detection and illumination control, and video image capture and processing techniques. By virtue of the present invention, the automatic digital-imaging based code symbol reading system ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments.

Abstract: An automatic automatically-triggered digital video-imaging based code symbol reading system for use in point of sale (POS) environments, employing an adaptive control process involving the real-time analysis of the exposure quality of captured frames of digital image data and the real-time reconfiguration of system control parameters (SCPs) based on the results of such exposure quality analysis. By virtue of the present invention, the system enables the reliable reading of code symbols graphically represented in digital images, under demanding point-of-sale lighting conditions and other challenging environments.

Abstract: An automatic digital video-imaging based code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video-imaging based code symbol reading techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing the versatility required to accommodate the different ways in which operators present objects for code symbol reading at POS environments.

Abstract: An automatic automatically-triggered digital video imaging based code symbol reading system for use in point of sale (POS) environments, employing an adaptive control process involving the real-time analysis of the exposure quality of captured frames of digital image data and the real-time reconfiguration of system control parameters (SCPs) based on the results of such exposure quality analysis. By virtue of the present invention, the system enables the reliable reading of code symbols graphically represented in digital images, under demanding point-of-sale lighting conditions and other challenging environments.

Abstract: An automatic digital video-imaging based code symbol reading system for use in point of sale (POS) environments, employing automatic illumination control, multi-tier modular software architecture and digital video-imaging based code symbol reading techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing the versatility required to accommodate the different ways in which operators present objects for code symbol reading at POS environments.

Abstract: An Automatically-triggered digital video-imaging based code symbol reading system providing a high degree of adaptability to ambient illumination levels and having great dynamic range. The system includes an illumination subsystem, having an active illumination mode and an ambient illumination mode. During object illumination and image capturing operations, the exposure quality of a captured frames of digital video image data is analyzed, and based on the results of such exposure quality analysis, system control parameters (SCPs) are automatically reconfigured. In the event that the exposure quality analysis indicates excessive exposure levels in captured frames of digital video image data, then a new set of SCPs is reconfigured, controlling the illumination subsystem to operate in its ambient illumination mode, whereby, ambient illumination is allowed to flood the field of view and form digital images on the image detection array during object illumination and video-imaging operations.

Abstract: An automatic digital video image capture and processing system supporting image-processing based code symbol reading during a pass-through mode of system operation at a retail point of sale (POS) station. The system comprises an automatic object direction detection subsystem, disposed in its housing, as well as an illumination subsystem, an image formation and detection subsystem, an automatic illumination control subsystem, a digital image capturing and buffering subsystem, a digital image processing subsystem, and a system control subsystem. During system operation, the automatic object direction detection subsystem automatically detects the presence and direction of movement of the object in the field of view (FOV), and in response thereto, generates a first signal indicating a triggering event and a second signal indicating the direction of movement of the object with respect to the FOV.

Abstract: An automatic code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video image capturing and processing techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing versatility required to accommodate the different ways in which human operators present objects for code symbol reading at POS environments.