Patents by Inventor Richard Jay Smeyne

Richard Jay Smeyne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detection of adenosine and metabolites thereof
    Patent number: 9528976
    Abstract: This invention relates is a label-free, enzyme-free, aptamer-free method for simultaneously measuring adenosine, and its intracellular metabolites, e.g., AMP, ADP and ATP, using high pressure liquid chromatography coupled to electrochemical detector (HPLC-ECD).
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: December 27, 2016
    Assignee: St. Jude Children's Research Hospital
    Inventors: Amar K. Pani, Richard Jay Smeyne
  • METHOD FOR DETECTION OF ADENOSINE AND METABOLITES THEREOF
    Publication number: 20160003797
    Abstract: This invention relates is a label-free, enzyme-free, aptamer-free method for simultaneously measuring adenosine, and its intracellular metabolites, e.g., AMP, ADP and ATP, using high pressure liquid chromatography coupled to electrochemical detector (HPLC-ECD).
    Type: Application
    Filed: February 28, 2014
    Publication date: January 7, 2016
    Applicant: St. Jude Children's Research Hospital
    Inventors: Amar K. Pani, Richard Jay Smeyne
  • Method for determining sensitivity to environmental toxins and susceptibility to parkinson's disease
    Publication number: 20040219600
    Abstract: The present invention relates to the identification of a gene encoding the protein glutathione S-transferase pi2 as being correlated with the susceptibility to neurotoxicity and concomitantly the risk to develop Parkinson's disease. Based on this correlation, various methods are disclosed, including determining the amount of the one or more glutathione S-transferase present in a biological sample in response to an environmental toxin, to assess the risk to develop Parkinson's disease.
    Type: Application
    Filed: December 12, 2003
    Publication date: November 4, 2004
    Inventors: Robert Wood Williams, Richard Jay Smeyne, Michelle Smeyne, Ruby Cook Tharpe, Elizabeth Cook