Abstract: Gas sensors are disclosed having an on-board, low-power data processor that uses multivariable gas classification and/or gas quantitation models to perform on-board data processing to resolve two or more gases in a fluid sample. To reduce computational complexity, the gas sensor utilizes low-power-consumption multivariable data analysis algorithms, inputs from available on-board sensors of ambient conditions, inputs representing contextual data, and/or excitation responses of a gas sensing material to select suitable gas classification and/or gas quantitation models. The data processor can then utilize these gas classification and quantitation models, in combination with measured dielectric responses of a gas sensing material of the gas sensor, to determine classifications and/or concentrations of two or more gases in a fluid sample, while consuming substantially less power than would be consumed if a global comprehensive model were used instead.

Abstract: Described herein are neuroactive steroids of the Formula (II): or a pharmaceutically acceptable salt thereof; wherein A, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6 and are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

Abstract: Apparatuses, systems, and methods for controlling cache allocations in a configurable combined private and shared cache in a processor-based system. The processor-based system is configured to receive a cache allocation request to allocate a line in a share cache structure, which may further include a client identification (ID). The cache allocation request and the client ID can be compared to a sub-non-uniform memory access (NUMA) (sub-NUMA) bit mask and a client allocation bit mask to generate a cache allocation vector. The sub-NUMA bit mask may have been programmed to indicate that processing cores associated with a sub-NUMA region are available, whereas processing cores associated with other sub-NUMA regions are not available, and the client allocation bit mask may have been programmed to indicate that processing cores are available.

Abstract: Provided herein are 19-nor C3, 3-disubstituted steroids of Formula (I): and pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4 are as defined herein, and A is a heteroaryl ring system comprising 3 or 4 nitrogens as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.

Abstract: Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.

Abstract: Gas sensors are disclosed having an on-board, low-power data processor that uses multivariable gas classification and/or gas quantitation models to perform on-board data processing to resolve two or more gases in a fluid sample. To reduce computational complexity, the gas sensor utilizes low-power-consumption multivariable data analysis algorithms, inputs from available on-board sensors of ambient conditions, inputs representing contextual data, and/or excitation responses of a gas sensing material to select suitable gas classification and/or gas quantitation models. The data processor can then utilize these gas classification and quantitation models, in combination with measured dielectric responses of a gas sensing material of the gas sensor, to determine classifications and/or concentrations of two or more gases in a fluid sample, while consuming substantially less power than would be consumed if a global comprehensive model were used instead.

Abstract: A hand immobilizing dexterity trainer glove for improving non-dominant hand dexterity includes a glove body having a dorsal side, a ventral side, a thumb side, and a pinky side. The glove body has a wrist aperture, a finger aperture, and a hand cavity extending from the wrist aperture to the finger aperture. The glove body is configured to receive a dominant hand of a user and extend from below a wrist to past a second knuckle of each finger of the user while covering a thumb of the user entirely within the hand cavity. A wrist tightening mechanism is coupled to the glove body proximal the wrist aperture to tighten and alternatively loosen the wrist aperture. A finger tightening mechanism is coupled to the glove body proximal the finger aperture to tighten and alternatively loosen the finger aperture. The hand immobilizing dexterity trainer glove renders the user's dominant hand unusable.

Abstract: An electronic tuning fork device including a control unit including a processor, electrically connected to an input unit and the display component, wherein the processor is configured to generate a first square wave signal and determine a gain parameter according to a predetermined mode, wherein the gain parameter is a value selected from between a predetermined maximum value and a predetermined minimum value, a frequency divider electrically connected to the processor, configured to down-convert the first square wave signal and output a second square wave signal, a first waveform conversion circuit, electrically connected to the processor, configured to convert the first square wave signal into a first sine wave signal, a second waveform conversion circuit, electrically connected to the frequency divider, configured to convert the second square signal into a second sine wave signal, a mixer, electrically connected to the first and second waveform conversion circuits, configured to mix the first sine wave sig

Abstract: An injected dose detection device including a housing having a joint surface surrounding an injection device, a vibration sensor disposed in an internal part of the housing configured to detect at least one vibration signal of a dose-setting action based on a minimum vibration threshold, an acoustic sensor disposed in the internal part of the housing configured to detect at least one dosage click of the dose-setting action, a vibration transmitting element positioned directly between the vibration sensor and the injection device and configured to transmit the at least one vibration signal and a processing unit configured to process the at least one vibration signal from the dose-setting action and the at least one dosage click from the dose-setting action for generating set dose information corresponding to the injected dose wherein a bottom plate and a side wall of the vibration transmitting element form a shell structure to cover the vibration sensor.

Abstract: A system for automatically obtaining a treatment record, comprising including a measuring device configured to measure a physiological parameter and configured to generate a state information and a first physiological parameter value for each measurement, wherein the measuring device includes at least one display screen, a database configured to store a treatment record after each measurement, wherein the treatment record includes a dosage value and a second physiological parameter value after taking the dosage, a computing device, connected to the measuring device and to the database, configured to obtain the treatment record from the database according to the state information and the first physiological parameter value wherein the computing device calculates a times of use ratio of the dosage from the obtained treatment record and calculates an average value of at least two of a plurality of the second physiological parameter values after taking the same amount of dosage; and wherein the measuring device d

Abstract: Various embodiments relate to a resetting mechanism for resetting a screw spindle of a drug delivery device including a driving element including two opposite driving pillars, connected to a sidewall and disposed in a chamber, a limiting element, movably engaged with the driving element, and two opposite clamping elements, movably disposed on two sides of the screw spindle, each of the clamping elements including a sliding base wherein the sliding base has a guide rail and a recess and a clamping jaw, connected to the sliding base and disposed in the chamber, wherein the opposite driving pillars slide in the guide rails along with the movement of the driving element, when the driving element moves toward the limiting element, the driving pillars drive the two clamping elements to move toward the screw spindle to make the two clamping jaws clamp the screw spindle and when the driving element moves away from the limiting element, the driving pillars drive the two clamping elements to move away from the screw sp

Abstract: Various embodiments relate to a resetting mechanism for resetting a screw spindle of a drug delivery device including a driving element including two opposite driving pillars, connected to a sidewall and disposed in a chamber, a limiting element, movably engaged with the driving element, and two opposite clamping elements, movably disposed on two sides of the screw spindle, each of the clamping elements including a sliding base wherein the sliding base has a guide rail and a recess and a clamping jaw, connected to the sliding base and disposed in the chamber, wherein the opposite driving pillars slide in the guide rails along with the movement of the driving element, when the driving element moves toward the limiting element, the driving pillars drive the two clamping elements to move toward the screw spindle to make the two clamping jaws clamp the screw spindle and when the driving element moves away from the limiting element, the driving pillars drive the two clamping elements to move away from the screw sp

Abstract: An injected dose detection device which includes a housing having a joint surface surrounding an injection device and a through hole formed on the joint surface configured to communicate with an internal part of the housing, a vibration sensor disposed in the internal part of the housing configured to detect at least one vibration signal based on a minimum vibration threshold, a vibration transmitting element positioned directly between the vibration sensor and the injection device and configured to transmit the at least one vibration signal and a processing unit configured to process the at least one vibration signal for generating injected dose information corresponding to the injected dose.

Abstract: A drug delivery device which includes a first housing part, a second housing part, a button, a drug expelling mechanism, a graduated plate, a circuit board and a pressing rod. The button is connected to the first housing part. The drug expelling mechanism is disposed inside the second housing part, and includes a dose setting member which is rotatable and configured to set a drug dose to be expelled. The graduated plate is disposed inside the first housing part and connected to the button, and includes a first conductive element and a plurality of second conductive element disposed on a surface thereof. The plurality of second conductive elements are arranged in interval and the first conductive element is electrically connected to the plurality of second conductive elements. The circuit board is disposed inside the first housing part and connected to the dose setting member.

Abstract: The present invention relates to a field of drug injection, and discloses a drug information detection device and a drug information detection type injection device. The drug information detection device is configured to detect an injected dose of an injection pen containing drug. The drug information detection device includes a housing, a rotary encoder configured to convert rotational information of the adjusting knob into drug injected dose information, and a control assembly. The rotary encoder includes an encoder body and a rotary block rotatably connected to the encoder body. The encoder body and the control assembly are electrically connected to each other. The housing is configured to cover the encoder body and the control assembly.

Abstract: The present invention relates to a field of drug injection, and discloses a drug information detection device and a drug information detection type injection device. The drug information detection device is configured to detect an injected dose of an injection pen containing drug. The drug information detection device includes a housing, a rotary encoder configured to convert rotational information of the adjusting knob into drug injected dose information, and a control assembly. The rotary encoder includes an encoder body and a rotary block rotatably connected to the encoder body. The encoder body and the control assembly are electrically connected to each other. The housing is configured to cover the encoder body and the control assembly.

Abstract: A protective garment is provided and includes a jacket having various releasably mounted protective components. The jacket includes a protective collar of ballistic resistant fabric for protecting the neck of a wearer and has front and rear portions which are releasably connected together at opposed side portions of the collar so that the front and rear portions can fold down when not in use. A protective plate is releasably fastened to the front of the jacket and the fastening mechanism allows the plate to be held in a number of different vertical positions. The jacket also includes a rear pocket for housing a rear protective plate. The sleeves of the jacket include a sleeve extension which is slideably mounted to the main sleeve to vary its effective length.

Abstract: A method of filtering streaming digital data in real time. The method including: (a) initializing and storing a set of m data elements and an associated set of m pointer data from 1 to m in sequence, m an integer greater than 2; (b) receiving in real time a first or next data element of a digital data stream of sequential data elements; (c) simultaneously with (b), replacing a stored data element associated with the pointer datum m with the received data element, changing the pointer datum of m to 1, and incrementing the value of all other pointer data by 1; (d) simultaneously with (b) sorting in order from a low to high all stored data elements; (e) simultaneously with (b), maintaining the association of pointer datum and data elements; (f) simultaneously with (b), filtering all stored data elements; and (g) repeating (b) through (f) multiple times.

Abstract: A circuit and design structure for a streaming digital data filter embodied in a machine readable medium, the design structure including: a data processing unit and a pointer processing unit, the data processing unit and the pointer unit connected to a control logic; the pointer processing unit consisting of n serially connected pointer processing stages from a first to a last pointer processing stage, each pointer processing stage except for the first and last processing stages of the pointer processing unit including a pointer register and a multiplexer, wherein n is a positive integer greater than 2; the data processing unit consisting of n serially connected data processing stages from a first data processing stage to a last data processing stage, each data processing stage including a multiplexer, a data register and a comparator; and one or more filter output stages connected to the data processing unit.