Patents by Inventor Richard Jund

Richard Jund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant having uracil phosphoribosyl transferase activity
    Patent number: 8211421
    Abstract: The invention concerns a polypeptide having a uracil phosphoribosyl transferase (UPRTase) by mutation of one or several residues of the UPRTase. The invention also concerns a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the latter, a viral particle, a host cell, and a composition containing them. The invention further concerns their therapeutic use and a treatment method using them. The invention is particularly useful in the context of therapy by suicide genes, in particular, for treating proliferative and infectious diseases.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: July 3, 2012
    Assignee: Transgene S.A.
    Inventors: Philippe Erbs, Richard Jund
  • MUTANT HAVING URACIL PHOSPHORIBOSYL TRANSFERASE ACTIVITY
    Publication number: 20100316610
    Abstract: The invention concerns a polypeptide having a uracil phosphoribosyl transferase (UPRTase) by mutation of one or several residues of the UPRTase. The invention also concerns a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the latter, a viral particle, a host cell, and a composition containing them. The invention further concerns their therapeutic use and a treatment method using them. The invention is particularly useful in the context of therapy by suicide genes, in particular, for treating proliferative and infectious diseases.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 16, 2010
    Applicant: TRANSGENE
    Inventors: Philippe ERBS, Richard Jund
  • Mutant having uracil phosphoribosyl transferase activity
    Patent number: 7572438
    Abstract: The invention concerns a polypeptide having a uracil phosphoribosyl transferase (UPRTase) by mutation of one or several residues of the UPRTase. The invention also concerns a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the latter, a viral particle, a host cell, and a composition containing them. The invention further concerns their therapeutic use and a treatment method using them. The invention is particularly useful in the context of therapy by suicide genes, in particular, for treating proliferative and infectious diseases.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: August 11, 2009
    Assignee: Transgene S.A.
    Inventors: Philippe Erbs, Richard Jund
  • Mutant having uracil phosphoribosyl transferase activity
    Publication number: 20060110363
    Abstract: The invention concerns a polypeptide having a uracil phosphoribosyl transferase (UPRTase) by mutation of one or several residues of the UPRTase. The invention also concerns a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the latter, a viral particle, a host cell, and a composition containing them. The invention further concerns their therapeutic use and a treatment method using them. The invention is particularly useful in the context of therapy by suicide genes, in particular, for treating proliferative and infectious diseases.
    Type: Application
    Filed: October 31, 2005
    Publication date: May 25, 2006
    Applicant: TRANSGENE
    Inventors: Philippe Erbs, Richard Jund
  • Mutant possessing uracil phosphoribosyl transferase activity
    Patent number: 7049117
    Abstract: The invention concerns a polypeptide having a uracil phosphoribosyl transferase (UPRTase) by mutation of one or several residues of the UPRTase. The invention also concerns a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the latter, a viral particle, a host cell, and a composition containing them. The invention further concerns their therapeutic use and a treatment method using them. The invention is particularly useful in the context of therapy by suicide genes, in particular, for treating proliferative and infectious diseases.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: May 23, 2006
    Assignee: Transgene S.A.
    Inventors: Philippe Erbs, Richard Jund
  • Mutant having uracil phosphoribosyl transferase activity
    Patent number: 6596533
    Abstract: The focus of the present invention is a polypeptide having a uracil phosphoribosyl transferase (UPRTase) activity achieved by mutation of one or more residues of the UPRTase. The invention also relates to a nucleotide sequence coding for the UPRTase mutant, a vector for expressing the nucleotide sequence, a viral particle, and a host cell, as well as a composition containing these. The invention further relates to the therapeutic use and method of treatment by using the mutant UPRTases and related compositions. The invention is particularly useful in the context of therapy by suicide genes, notably for treating proliferative and infectious diseases.
    Type: Grant
    Filed: August 14, 2000
    Date of Patent: July 22, 2003
    Assignee: Transgene S.A.
    Inventors: Philippe Erbs, Richard Jund