Patents by Inventor Richard K. Haynes

Richard K. Haynes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10111884
    Abstract: The present invention provides compositions and methods for treating, preventing, and inhibiting viral replication, viral infections and viral diseases and disorders, comprising the use of artemisinin derivatives having anti-viral activity.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: October 30, 2018
    Assignees: Hadasit Medical Research Services and Development Ltd., The Hong Kong University of Science and Technology
    Inventors: Richard K. Haynes, Dana G. Wolf
  • Patent number: 9616067
    Abstract: The present invention provides compositions and methods for treating, preventing, and inhibiting viral replication, viral infections and viral diseases and disorders, comprising the use of artemisinin derivatives having anti-viral activity.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: April 11, 2017
    Assignees: Hadasit Medical Research Services and Development Ltd., The Hong Kong University of Science and Technology
    Inventors: Richard K. Haynes, Dana G. Wolf
  • Publication number: 20170071952
    Abstract: The present invention provides compositions and methods for treating, preventing, and inhibiting viral replication, viral infections and viral diseases and disorders, comprising the use of artemisinin derivatives having anti-viral activity.
    Type: Application
    Filed: November 25, 2016
    Publication date: March 16, 2017
    Applicants: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
    Inventors: Richard K. HAYNES, Dana G. WOLF
  • Publication number: 20150072979
    Abstract: The present invention provides compositions and methods for treating, preventing, and inhibiting viral replication, viral infections and viral diseases and disorders, comprising the use of artemisinin derivatives having anti-viral activity.
    Type: Application
    Filed: April 17, 2013
    Publication date: March 12, 2015
    Applicants: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT
    Inventors: Richard K. Haynes, Dana G. Wolf
  • Patent number: 7452915
    Abstract: This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substituted derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: November 18, 2008
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Richard K. Haynes, William Wai-Lun Lam, Ho-Wai Chan, Hing-Wo Tsang, Man-Ki Cheung, Gisela Greif, Gabriele Schmuck, Arnd Voerste
  • Patent number: 7439238
    Abstract: This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substitued derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
    Type: Grant
    Filed: January 9, 2006
    Date of Patent: October 21, 2008
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Richard K. Haynes, William Wai-Lun Lam, Ho-Wai Chan, Hing-Wo Tsang, Man-Ki Cheung, Gisela Greif, Gabriele Schmuck, Arnd Voerste
  • Patent number: 6984640
    Abstract: This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substituted deriviatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: January 10, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Richard K. Haynes, William Wai-Lun Lam, Ho-Wai Chan, Hing-Wo Tsang, Man-Ki Cheung, Gisela Greif, Gabriele Schmuck, Arnd Voerste
  • Patent number: 5420299
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: May 30, 1995
    Assignee: The University of Sydney
    Inventors: Richard K. Haynes, Simone C. Vonwiller
  • Patent number: 5310946
    Abstract: A process for preparing a compound containing (a) peroxyacetal lactone, (b) peroxyacetal lactol or (c) peroxycacetal ether functionality comprising oxygenating in the presence of one or more oxidizing metal catalysts a compound containing (i) hydroperoxy alkene carboxylic acid, (ii) hydroperoxy alkene aldehyde, (iii) hydroperoxy alkene keto, (iv) hydroperoxy alkene alcohol functionality or (v) dialkyl acetals of compounds in (ii) and (iii) above. For example (I).fwdarw.(II) wherein n=1,2 or 3; m=0, 1, 2,; p=0, 1, 2 or 3; R.sup.5 =--COOH, --C(O)R, --CROH, (.alpha.), where R is H, alkyl, aryl or arylalkyl; R.sup.1 are independently alkyl, arylalkyl or each R.sup.1 together with the group --O--C--O-- to which they are attached form a cyclic acetal; X=CR.sup.2 R .sup.3, O, S, SO, SO.sub.2 where R.sup.2 and R.sup.
    Type: Grant
    Filed: March 26, 1992
    Date of Patent: May 10, 1994
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Richard K. Haynes, Simone C. Vonwiller