Abstract: Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.

Abstract: The present invention describes the preparation of an aqueous polyurethane dispersion which is cured by radiation, and its use as binder.

Abstract: The present invention describes the preparation of an aqueous polyurethane dispersion which is cured by radiation, and its use as binder.

Abstract: The invention relates to novel UV-curable polyurethane dispersions based on unsaturated polyesters modified with dicyclopentadiene, the preparation of these polyurethane dispersions and the use thereof as a lacquer, coating and/or adhesive.

Abstract: The present invention provides a mixture containing a) at least 26 wt. % of gadolinium and b) one or more elements, alloys and/or compounds from the group consisting of barium, indium, tin, lanthanum, molybdenum, niobium, tantalum, zirconium and tungsten, a process for the preparation of this mixture, use of the mixture as radiation protection, use of the mixture to prepare polymeric radiation protection substances, a process for preparing radiation screening rubbers, thermoplastic materials and polyurethanes, a process for preparing products from the polymeric radiation protection substances and products made from these polymeric radiation protection substances.

Abstract: The present invention provides a mixture containing a) at least 26 wt. % of gadolinium and b) one or more elements, alloys and/or compounds from the group consisting of barium, indium, tin, lanthanum, molybdenum, niobium, tantalum, zirconium and tungsten, a process for the preparation of this mixture, use of the mixture as radiation protection, use of the mixture to prepare polymeric radiation protection substances, a process for preparing radiation screening rubbers, thermoplastic materials and polyurethanes, a process for preparing products from the polymeric radiation protection substances and products made from these polymeric radiation protection substances.

Abstract: A distinct male cultivar of Salix purpurea×S. miyabeana named ‘Oneida’, characterized by rapid stem growth producing 2.7-times greater woody biomass than one of its parents (‘SX67’) and greater than 36% more biomass than current production cultivars (‘SV1’ and ‘SX64’). ‘Oneida’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Oneida’ displays a low incidence of rust disease or damage by beetles or sawflies.

Abstract: A distinct female cultivar of Salix viminalis×S. miyabeana named ‘Tully Champion’, characterized by rapid stem growth producing greater than 25% more woody biomass than two current production clones (Salix dasyclados ‘SV1’ and Salix miyabeana ‘SX64’), more than 2.5-fold greater biomass than one of its parents (Salix miyabeana ‘SX67’), and nearly 3-fold more biomass than another production clone (Salix sacchalinensis, ‘SX61’) when grown in the same field for the same length of time (two growing seasons after coppice) in Tully, N.Y. ‘Tully Champion’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested repeatedly after two to four years of growth. ‘Tully Champion’ displays a low incidence of rust disease and is not damaged by potato leafhoppers.

Abstract: A distinct male cultivar of Salix sachalinensis×S. miyabeana named ‘Canastota’, characterized by rapid stem growth producing greater than 2.7-fold more woody biomass than its female parent (Salix sachalinensis ‘SX61’), 28% greater woody biomass yield than its male parent (Salix miyabeana ‘SX64’), and 20% greater woody biomass yield than a standard production cultivar, Salix dasyclados ‘SV1’ when grown in the same field for the same length of time (two growing seasons after coppice) in Tully, N.Y. ‘Canastota’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. ‘Canastota’ displays a low incidence of rust disease or damage by willow sawfly.

Abstract: A distinct female cultivar of Salix viminalis×Salix miyabeana named ‘Owasco’, characterized by rapid stem growth producing greater than 49% more woody biomass than one of its parents (‘SX64’) and 39% more biomass than a current production cultivar (‘SV1’). ‘Otisco’ produced greater than 2.7-fold more stem biomass than two other current production cultivars, ‘SX67’ and ‘SX61’. ‘Owasco’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Owasco’ displays a low incidence of rust disease and is not damaged by potato leafhoppers.

Abstract: A distinct female cultivar of Salix viminalis×S. miyabeana named ‘Otisco’, characterized by rapid stem growth producing greater than 42% more woody biomass than one of its parents (‘SX64’) and 33% more biomass than a current production cultivar (‘SV1’). ‘Otisco’ produced greater than 2.5-fold more stem biomass than two other current production cultivars, ‘SX67’ and ‘SX61’. ‘Otisco’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Otisco’ displays a low incidence of rust disease and is not damaged by potato leafhoppers.

Abstract: A distinct female cultivar of Salix purpurea×Salix miyabeana named ‘Millbrook’, characterized by rapid stem growth producing 9% more woody biomass than one of its parents (‘SX64’) and 2% more biomass than a current production cultivar (‘SV1’). ‘Millbrook’ produced greater than 2-fold more stem biomass than two other current production cultivars, ‘SX67’ and ‘SX61’. ‘Millbrook’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Millbrook’ displays a low incidence of rust disease.

Abstract: A distinct male cultivar of Salix purpurea named ‘Fish Creek’, characterized by rapid stem growth producing greater than 30% more woody biomass than either of its parents (‘94001’ and ‘94006’) and 20% more biomass than a current production cultivar (‘SV1’). ‘Fish Creek’ can be planted from dormant stem cuttings, produces multiple stems after coppice, and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested after two to four years of growth. This harvest cycle can be repeated several times. The stem biomass can be chipped and burned as a source of renewable energy, generating heat and/or electricity. ‘Fish Creek’ displays a low incidence of rust disease or damage by beetles or sawflies.

Abstract: The present invention relates to aqueous polyurethane dispersions that are free from N-methylpyrrolidone and other solvents and wherein the polyurethanes are the reaction products of A) a mixture of 25% to 90% by weight of 1-isocyanate-3,3,5,-trimethyl-5-isocyanatomethylcyclohexane (IPDI) and 10% to 75% by weight of 4,4?-diisocyanatodicyclohexylmethane, wherein the preceding percentages are based on the weight of component A), with B) one or more polyols having average molarcular weights (Mn) of 500 to 6000, C) one or more compounds which have at least one OH— or NH-functional group and contain a carboxyl and/or carboxylate group, wherein at least 50 mol % of the acid groups, based on the total moles of acid incorporated into the polyurethane, are incorporated by dimethylolpropionic acid, D) one or more polyols and/or polyamines having average molecular weights (Mn) of below 500, and E) optionally one or more monoalcohols and/or monoamines.

Abstract: The present invention relates to water-free and cosolvent-free binder compositions A) containing of a mixture of A1) at least one emulsifier-free, hydrophobic binder containing groups which can be polymerized by high-energy radiation and A2) at least one hydrophilic unsaturated polyester resin containing the reaction product of a) at least one unsaturated dicarboxylic acid and/or an anhydride thereof, b) at least one polyalkylene oxide compound having a number average molecular weight of 106 to 2000, at least 2 hydroxyl end groups and at least 2 oxyalkylene units, wherein at least 50% of the oxyalkylene units are oxyethylene units, and c) at least one hydroxy-functional compound containing at least one polymerizable unsaturated group per molecule selected from vinyl, allyl, methacrylic and acrylic groups.

Abstract: Non-crystallizing N,N′-disubstituted N-(2-hydroxyalkyl)-ureas are used as hydrolysis protection agents in plastics containing ester groups. These disubstituted hydroxy-alkylureas impart excellent protection from hydrolysis to plastics containing ester groups and can be added directly to the plastics to be stabilized without the addition of special solvents.

Abstract: Free-flowing compression molding compositions made up of from about 40 to about 80 wt. % of organic filler, from about 20 to about 60 wt. % of an organic reactive resin, and optionally further auxiliary substances and additives. The reactive resin contains an epoxide which may be liquid, a latent catalyst and a powdered polyisocyanate which is solid at room temperature.

Abstract: The present invention relates to a heat curable, one-component polyurethane reactive compositions containingA) surface-modified, finely divided polyisocyanates in which 0.1 to 25 equivalent percent, based on the total number of NCO groups, of the NCO groups are deactivated andB) a mixture of relatively high molecular weight compounds having isocyanate-reactive groups containing1) 5 to 40 wt. %, based on the weight of component B), of one or more aliphatic polyether polyamines and2) 60 to 95 wt. %, based on the weight of component B), of a polyol mixture containingi) 10 to 60 wt. %, based on the weight of component B2), of at least one polyester polyol andii) 40 to 90 wt. %, based on the weight of component B2), of at least one polyether polyol with predominantly primary hydroxyl groups.The present invention also relates to use of the heat curable, one-component polyurethane reactive compositions to prepare coatings, adhesives, anti-drumming products and sealants, especially seam sealants.

Abstract: The present invention is directed to novel urea group-containing polyisocyanates modified with long chain compounds having molecular weights of 400 to about 10,000. The present invention is also directed to a process for the preparation of modified urea group-containing polyisocyanates by reacting starting polyisocyanates which are free from urea groups with water to form urea groups in an inert reaction medium or in an aqueous mixture containing a dispersion stabilizer, wherein the starting polyisocyanates are mixed or reacted with long chain compounds having molecular weights of 400 to about 10,000 before the reacting the starting polyisocyanates with water and/or the long chain compounds are added to the inert reaction medium and/or to the water.

Abstract: The present invention relates to a process for the preparation of a modified 1,5-naphthylene diisocyanate containing urea and biuret groups comprising reacting(a) 1,5-naphthylene diisocyanate in molten form with(b) a mixture comprising about 0.02 to about 0.5 mole of water per mole of 1,5-naphthylene diisocyanate and about 1 to about 10 parts for each part of water of an organic solvent.The present invention further relates to a process for the preparation of elastomeric moldings comprising reacting by the one-shot or prepolymer process at an isocyanate index of 70 to 130 a modified 1,5-naphthylene diisocyanate containing urea and biuret groups with compounds containing at least two isocyanate-reactive groups and having a molecular weight in the range from about 500 to about 10,000 and, optionally, organic compounds containing isocyanate-reactive groups and having a molecular weight in the range from 60 to 499.