Abstract: An example system includes a first lead configured to be positioned in or beside a left internal jugular vein (IJV) of a patient to deliver a first stimulation signal to a first vagus nerve, the first lead including one or more first segmented electrodes positioned on a distal portion of the first lead and a first anchoring mechanism; a second lead configured to be positioned in or beside a right IJV of the patient to deliver a second stimulation signal to a second vagus nerve, the second lead including one or more second segmented electrodes positioned on a distal portion of the second lead and a second anchoring mechanism; and circuitry configured to deliver electrical energy to the first lead to deliver the first stimulation signal and the second lead to deliver the second stimulation signal to provide bilateral stimulation to the first vagus nerve and the second vagus nerve.

Abstract: This patent describes a new orthodontic instrument to be used for tying or twisting the ligature wires used to hold the arch wire to the bracket. It also explains the method of use which consists of: twisting the wires, after the ligature wire has been placed on the bracket; tucking the twisted end out of the way; and then breaking the end at the tip of the instrument. The instrument replaces three instruments normally used, by improvements in jaw design to facilitate grasping and centering the wires for spinning, balancing the instrument by general symmetry, and the addition of an extension handle to allow rapid spinning, and tucking of the wire ends as they are broken in a controlled manner, and at a specific place. The instrument thus simplifies, speeds and further improves the application of ligature wires.