Patents by Inventor Richard L. Friedman

Richard L. Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8715679
    Abstract: The present invention relates to pili obtained from Mycobacterium tuberculosis, methods of producing the pili and the use of the pili for inducing an immune response against Mycobacterium tuberculosis. The present invention also provides proteins and peptides which are constituents of the pili. Antibodies which bind to the pili are also provided.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: May 6, 2014
    Assignee: The Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Richard L. Friedman, Jorge A. Giron, Christopher J. Alteri
  • Patent number: 7919258
    Abstract: Methods for diagnosing Mycobacterium tuberculosis infection in a human that include providing blood serum, contacting the serum with an Eis antigen fixed on a substrate, thereby forming complexes of Eis antigen with a human antibody that binds to the Eis antigen, contacting the antibody/Eis complexes with a labeled anti-human secondary antibody, and measuring a titer of the human antibody bound to the Eis antigen. In addition, statistically significant positive or negative diagnosis of infection with Mycobacterium tuberculosis is provided by comparing patient serum antibody titer with a second titer from a negative control blood sample.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: April 5, 2011
    Assignee: Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Richard L. Friedman, Linoj P. Samuel
  • Publication number: 20080138356
    Abstract: The present invention relates to pili obtained from Mycobacterium tuberculosis, methods of producing the pili and the use of the pili for inducing an immune response against Mycobacterium tuberculosis. The present invention also provides proteins and peptides which are constituents of the pili. Antibodies which bind to the pili are also provided.
    Type: Application
    Filed: February 9, 2005
    Publication date: June 12, 2008
    Applicant: The AZ Bd of Regents on Behalf of the Univ. of AZ
    Inventors: Richard L. Friedman, Jorge A. Giron, Christopher J. Alteri