Abstract: A method for flagging journal entries within a general ledger is described. A plurality of assessment routines are executed on transaction lines of the journal entries within the general ledger, each assessment routine of the plurality of assessment routines i) being configured to generate a base score for each transaction line, and ii) associated with a corresponding flagging threshold. A composite score is generated for each transaction line using the base scores generated by the plurality of assessment routines. For each journal entry within the general ledger: the journal entry is flagged when one or more base scores for the journal entry exceed the corresponding flagging thresholds of the assessment routines, or when none of the base scores for the journal entry exceed the corresponding flagging thresholds and the composite score exceeds a composite threshold. A report of flagged journal entries is generated.

Abstract: A method for flagging journal entries within a general ledger is described. A plurality of assessment routines are executed on transaction lines of the journal entries within the general ledger, each assessment routine of the plurality of assessment routines i) being configured to generate a base score for each transaction line, and ii) associated with a corresponding flagging threshold. A composite score is generated for each transaction line using the base scores generated by the plurality of assessment routines. For each journal entry within the general ledger: the journal entry is flagged when one or more base scores for the journal entry exceed the corresponding flagging thresholds of the assessment routines, or when none of the base scores for the journal entry exceed the corresponding flagging thresholds and the composite score exceeds a composite threshold. A report of flagged journal entries is generated.

Abstract: An x-ray source for use in Phase Contrast Imaging is disclosed. In particular, the x-ray source includes a cathode array of individually controlled field-emission electron guns. The field emission guns include very small diameter tips capable of producing a narrow beam of electrons. Beams emitted from the cathode array are accelerated through an acceleration cavity and are directed to a transmission type anode, impinging on the anode to create a small spot size, typically less than five micrometers. The individually controllable electron guns can be selectively activated in patterns, which can be advantageously used in Phase Contrast Imaging.

Abstract: Described here is a method for performing phase contrast imaging using an array of independently controllable x-ray sources. The array of x-ray sources can be controlled to produce a distinct spatial pattern of x-ray radiation and thus can be used to encode phase contrast signals without the need for a coded aperture. The lack of coded aperture increases the flexibility of the imaging method. For instance, because a fixed, coded aperture is not required, the angular resolution of the imaging technique can be increased as compared to coded-aperture imaging. Moreover, the lack of a radioopaque coded aperture increases the photon flux that reaches the subject, thereby increasing the attainable signal-to-noise ratio.

Abstract: Described here is a method for performing phase contrast imaging using an array of independently controllable x-ray sources. The array of x-ray sources can be controlled to produce a distinct spatial pattern of x-ray radiation and thus can be used to encode phase contrast signals without the need for a coded aperture. The lack of coded aperture increases the flexibility of the imaging method. For instance, because a fixed, coded aperture is not required, the angular resolution of the imaging technique can be increased as compared to coded-aperture imaging. Moreover, the lack of a radioopaque coded aperture increases the photon flux that reaches the subject, thereby increasing the attainable signal-to-noise ratio.

Abstract: An x-ray source for use in Phase Contrast Imaging is disclosed. In particular, the x-ray source includes a cathode array of individually controlled field-emission electron guns. The field emission guns include very small diameter tips capable of producing a narrow beam of electrons. Beams emitted from the cathode array are accelerated through an acceleration cavity and are directed to a transmission type anode, impinging on the anode to create a small spot size, typically less than five micrometers. The individually controllable electron guns can be selectively activated in patterns, which can be advantageously used in Phase Contrast Imaging.

Abstract: A radiation detection system that measures radiation (e.g., signature energy-level gamma radiation and neutrons) is employed aboard a ship or other transport vehicle along with conventional cargo to monitor for the presence of a fissile material, as would be found in a nuclear weapon, or for the presence of other sources of radiation. The detection system can be used over the course of the cargo transport, thereby enabling finely tuned monitoring for fissile material across distances of many meters extending through surrounding cargo containers. Because the system can be utilized during a ship's transport, a positive detection of fissile material can be made and acted upon while the ship is still at sea far from the destination port, where detonation of a nuclear weapon could have catastrophic consequences.

Abstract: The invention relates to imaging systems that include a coded aperture detection system and an optical detection system. The coded aperture detection system is configured to detect radiation emitted by a radionuclide present within an object and to provide a first detector signal from the detected radiation. The optical detection system is configured to detect optical radiation from the object and to provide a second detector signal from the detected optical radiation. The system also includes a processor configured to prepare first image data from the first detector signal, second image data from the second detector signal, and registered data indicative of a spatial relationship in at least one dimension between the first and second image data. The invention also includes methods of using the new systems, e.g., for sentinel lymph node mapping and tissue resection.

Abstract: An apparatus, and method, are disclosed for producing a high specific activity of a radioisotope in a single increment of target material, or sequentially within in-series increments of target material, by exposing a targeted isotope in the target material to a high energy photon beam to isotopically convert the targeted isotope. In particular, this invention is used to produce a high specific activity of Mo99, of at least 1.0 Ci/gm or preferably at least about 10.0 Ci/gm, from Mo100.

Abstract: An apparatus, and method, are disclosed for producing a high specific activity of a radioisotope in a single increment of target material, or sequentially within in-series increments of target material, by exposing a targeted isotope in the target material to a high energy photon beam to isotopically convert the targeted isotope. In particular, this invention is used to produce a high specific activity of Mo.sup.99, of at least 1.0 Ci/gm or preferably at least about 10.0 Ci/gm, from Mol.sup.100.

Abstract: An apparatus, and method, are disclosed for producing a high specific activity of a radioisotope in a single increment of target material, or sequentially within in-series increments of target material, by exposing a targeted isotope in the target material to a high energy photon beam to isotopically convert the targeted isotope. In particular, this invention is used to produce a high specific activity of Mo.sup.99, of at least 1.0 Ci/gm or preferably at least about 10.0 Ci/gm, from Mo.sup.100.