Patents by Inventor Richard Lifton

Richard Lifton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for diagnosing and treating diseases and disorders associated with mutant KCNJ5
    Patent number: 11484543
    Abstract: The present invention relates to the discovery that mutant KCNJ5 is associated with adrenal diseases and disorders. The invention includes compositions and methods for the diagnosis and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: November 1, 2022
    Assignee: The Rockefeller University
    Inventors: Richard Lifton, Ute Scholl
  • COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH MUTANT KCNJ5
    Publication number: 20200147113
    Abstract: The present invention relates to the discovery that mutant KCNJ5 is associated with adrenal diseases and disorders. The invention includes compositions and methods for the diagnosis and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder.
    Type: Application
    Filed: May 18, 2018
    Publication date: May 14, 2020
    Inventors: Richard Lifton, Ute Scholl
  • Methods for identifying subjects with a genetic risk for developing IgA nephropathy
    Patent number: 10358678
    Abstract: Seven protective alleles for IgA nephropathy have been discovered that can be identified by analyzing a DNA sample for seven respective SNPs. A method is provided for identifying and treating subjects at risk of developing IgA neuropathy based on a new seven-SNP genetic risk score. Also provided are screening methods to identify compounds that bind to and reduce the expression or biological activity of a either CFHR1 or CFHR3.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: July 23, 2019
    Assignees: The Trustees of Columbia University in the City of New York, Yale University
    Inventors: Ali Gharavi, Krzysztof Kiryluk, Richard Lifton
  • Methods for Identifying Subjects with a Genetic Risk for Developing IgA Nephropathy
    Publication number: 20170226586
    Abstract: Seven protective alleles for IgA nephropathy have been discovered that can be identified by analyzing a DNA sample for seven respective SNPs. A method is provided for identifying and treating subjects at risk of developing IgA neuropathy based on a new seven-SNP genetic risk score. Also provided are screening methods to identify compounds that bind to and reduce the expression or biological activity of a either CFHR1 or CFHR3.
    Type: Application
    Filed: February 20, 2017
    Publication date: August 10, 2017
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Ali Gharavi, Krzysztof Kiryluk, Richard Lifton
  • Methods for identifying subjects with a genetic risk for developing IgA nephropathy
    Patent number: 9598733
    Abstract: Seven protective alleles for IgA nephropathy have been discovered that can be identified by analyzing a DNA sample for seven respective SNPs. A method is provided for identifying and treating subjects at risk of developing IgA neuropathy based on a new seven-SNP genetic risk score. Also provided are screening methods to identify compounds that bind to and reduce the expression or biological activity of a either CFHR1 or CFHR3.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: March 21, 2017
    Assignees: The Trustees of Columbia University in the City of New York, Yale University
    Inventors: Ali Gharvari, Krzysztof Kiryluk, Richard Lifton
  • Assays for Detecting WDR62 Mutations
    Publication number: 20170067109
    Abstract: The present invention relates to compositions and methods for detecting mutations in WD repeat domain 62 (WDR62).
    Type: Application
    Filed: September 23, 2016
    Publication date: March 9, 2017
    Inventors: Murat Gunel, Richard Lifton, Matthew State, Kaya Bilguvar
  • Assays for detecting WDR62 mutations
    Patent number: 9464323
    Abstract: The present invention relates to compositions and methods for detecting mutations in WD repeat domain 62 (WDR62).
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: October 11, 2016
    Assignee: Yale University
    Inventors: Murat Gunel, Richard Lifton, Matthew State, Kaya Bilguvar
  • Compositions and Methods for Diagnosing, Preventing and Treating Intracranial Aneurysms
    Publication number: 20150044239
    Abstract: The present invention relates to compositions and methods for diagnosing, preventing and treating intracranial aneurysm.
    Type: Application
    Filed: March 30, 2012
    Publication date: February 12, 2015
    Applicant: YALE UNIVERSITY
    Inventors: Richard Lifton, Murat Gunel
  • ASSAYS FOR DETECTING WDR60 MUTATIONS
    Publication number: 20130261002
    Abstract: The present invention relates to compositions and methods for detecting mutations in WD repeat domain 62 (WDR62).
    Type: Application
    Filed: June 30, 2011
    Publication date: October 3, 2013
    Inventors: Murat Gunel, Richard Lifton, Matthew State, Kaya Bilguvar