Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.

Abstract: Illustrative embodiments provide automated methods and systems for generating customer communications through analysis of known data of the customer, and data derived from third-party systems such as social media platforms and government data sources. Some embodiments provide automated methods and systems that produce, based on past interactions with a customer, a set of future interactions for execution by a sender. The set of future interactions is preferably configured, relative to a previous set of interactions, to increase the likelihood of a favorable response from the customer.

Abstract: Illustrative embodiments provide automated methods and systems for generating customer communications through analysis of known data of the customer, and data derived from third-party systems such as social media platforms and government data sources. Some embodiments provide automated methods and systems that produce, based on past interactions with a customer, a set of future interactions for execution by a sender. The set of future interactions is preferably configured, relative to a previous set of interactions, to increase the likelihood of a favorable response from the customer.

Abstract: A candy package is provided, having a container and an openable lid or closure, with the container being divided into a plurality of cells. A plurality of candies are provided in each cell, with the candies simulating the appearances of various forms of fishing tackle and the container and lid simulating the appearance of a fishing tackle box.