Patents by Inventor Richard M. Silver

Richard M. Silver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190352368
    Abstract: The invention provides anti-fibrotic peptides derived from the C-terminal region of the MET receptor tyrosine kinase. Polynucleotides encoding these peptides, host cells transformed with the polynucleotides, and methods of using these peptides and polynucleotides are included in the invention. Uses of these peptides, polynucleotides and expression vectors include the treatment of fibrosis in a subject.
    Type: Application
    Filed: June 14, 2019
    Publication date: November 21, 2019
    Inventors: Galina S. Bogatkevich, Yuichiro Shirai, Richard M. Silver
  • Patent number: 10344071
    Abstract: The invention provides anti-fibrotic peptides derived from the C-terminal region of the MET receptor tyrosine kinase. Polynucleotides encoding these peptides, host cells transformed with the polynucleotides, and methods of using these peptides and polynucleotides are included in the invention. Uses of these peptides, polynucleotides and expression vectors include the treatment of fibrosis in a subject.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: July 9, 2019
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Galina S. Bogatkevich, Yuichiro Shirai, Richard M. Silver
  • Publication number: 20180215802
    Abstract: The invention provides anti-fibrotic peptides derived from the C-terminal region of the MET receptor tyrosine kinase. Polynucleotides encoding these peptides, host cells transformed with the polynucleotides, and methods of using these peptides and polynucleotides are included in the invention. Uses of these peptides, polynucleotides and expression vectors include the treatment of fibrosis in a subject.
    Type: Application
    Filed: July 21, 2016
    Publication date: August 2, 2018
    Inventors: Galina S. Bogatkevich, Yuichiro Shirai, Richard M. Silver
  • Patent number: 7812943
    Abstract: A method of imaging critical dimensions by measuring the zeroeth order of diffracted light. The method involves providing a target, directing light onto the target so as to cause the target to diffract the light. The zeroeth order of the diffracted light is collected and analyzed to determine structural features of the target. The target can be an article of manufacture, such as a semiconductor device, or a separate target that is provided or fabricated on an article of manufacture. One of at least the wavelength and the angle at which the light is directed onto the target can be scanned. The target can fill all or only a portion of the field of view.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: October 12, 2010
    Assignees: The United States of America as represented by the Secretary of Commerce, The National Institute of Standards and Technology
    Inventors: Richard M. Silver, Ravikiran Attota, Robert Larrabee
  • Publication number: 20090109446
    Abstract: A method of imaging critical dimensions by measuring the zeroeth order of diffracted light. The method involves providing a target, directing light onto the target so as to cause the target to diffract the light. The zeroeth order of the diffracted light is collected and analyzed to determine structural features of the target. The target can be an article of manufacture, such as a semiconductor device, or a separate target that is provided or fabricated on an article of manufacture. One of at least the wavelength and the angle at which the light is directed onto the target can be scanned. The target can fill all or only a portion of the field of view.
    Type: Application
    Filed: October 29, 2007
    Publication date: April 30, 2009
    Inventors: Richard M. Silver, Ravikiran Attota, Robert Larrabee
  • Patent number: 5542934
    Abstract: A hypodermic syringe designed to simultaneously dispense anesthetic liquid from a plurality of carpules. In a preferred embodiment, the syringe comprises a body which includes a pair of parallel, open-ended, generally cylindrical members and a base member. The cylindrical members are partially inserted into and fixedly secured within the base member. Each cylindrical member is shaped to include an elongated chamber adapted to removably receive therewithin an anesthetic liquid-containing carpule. The base member is externally-shaped to define a finger-gripping handle. The syringe also includes a fluid mixing chamber for receiving fluid drawn from each of the carpules through a corresponding fluid transport assembly mounted within the open top end of the respective cylindrical member, the fluid mixing chamber being formed by the mating engagement of an externally-threaded disk and an internally-threaded cap.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: August 6, 1996
    Inventor: Richard M. Silver