Patents by Inventor Richard M. Thorn

Richard M. Thorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systemic purine administration: modulating axonal outgrowth of central nervous system neurons
    Patent number: 8133861
    Abstract: Methods for modulating the axonal outgrowth of central nervous system neurons are provided by means of internalized purine administration such as by intravenous, intraarterial, subcutaneous, intramuscular, intraperitoneal, and intrapleural administration. The methods are noted for stimulating the axonal outgrowth of central nervous system neurons following an injury (e.g., stroke, traumatic brain injury, cerebral aneurism, spinal cord injury and the like).
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: March 13, 2012
    Assignee: Alseres Pharmaceuticals, Inc.
    Inventors: Noel James Cusack, Mark R. Hurtt, Richard M. Thorn
  • SYSTEMIC PURINE ADMINISTRATION: MODULATING AXONAL OUTGROWTH OF CENTRAL NERVOUS SYSTEM NEURONS
    Publication number: 20090221521
    Abstract: Methods for modulating the axonal outgrowth of central nervous system neurons are provided by means of internalized purine administration such as by intravenous, intraarterial, subcutaneous, intramuscular, intraperitoneal, and intrapleural administration. The methods are noted for stimulating the axonal outgrowth of central nervous system neurons following an injury (e.g., stroke, traumatic brain injury, cerebral aneurism, spinal cord injury and the like).
    Type: Application
    Filed: February 26, 2009
    Publication date: September 3, 2009
    Applicant: Alseres Pharmaceuticals, Inc.
    Inventors: Mark R. Hurtt, Noel James Cusack, Richard M. Thorn
  • METHODS OF INHIBITING ANGIOGENESIS WITH FRAGMENTS AND HOMOLOGS OF TROPONIN SUBUNIT I
    Publication number: 20090156491
    Abstract: The present invention relates to methods of inhibiting angiogenesis associated with a disease or disorder with peptides homolgous to amino acid residues 130-137 or 132-139 of human troponin subunit I.
    Type: Application
    Filed: October 20, 2008
    Publication date: June 18, 2009
    Applicants: CHILDREN'S MEDICAL CENTER CORPORATION, INC., ALSERES PHARMACEUTICALS, INC.
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Methods of inhibiting angiogenesis with fragments and homologs of troponin subunit 1
    Patent number: 7452866
    Abstract: The present invention relates to methods of inhibiting angiogenesis associated with a disease or disorder with peptides homologous to amino acid residues 130-137 or 132-139 of human troponin subunit I.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: November 18, 2008
    Assignees: Children's Medical Center Corporation, Alseres Pharmaceuticals, Inc.
    Inventors: Richard M. Thorn, Mark A. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Methods of inhibiting angiogenesis with fragments and homologs of troponin subunit I
    Patent number: 7078385
    Abstract: The present invention relates to methods of inhibiting angiogenesis associated with a disease or disorder with peptides homologous to amino acid residues 130–137 or 132–139 of human troponin subunit I.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: July 18, 2006
    Assignees: Boston Life Sciences, Inc., Children's Medical Center Corporation
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Methods of inhibiting angiogenesis with fragments and homologs of troponin subunit I
    Publication number: 20030186864
    Abstract: The present invention relates to pharmaceutical compositions comprising therapeutically effective amounts of troponin C, I or T subunits, fragments or homologs for the treatment of diseases or disorders involving abnormal angiogenesis and methods of use thereof.
    Type: Application
    Filed: June 18, 2002
    Publication date: October 2, 2003
    Applicant: Boston Life Sciences, Inc.
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Pharmaceutical compositions comprising recombinant troponin subunits
    Patent number: 6589936
    Abstract: The present invention relates to pharmaceutical compositions comprising therapeutically effective amounts of recombinant troponin C, I or T subunits for the treatment of diseases or disorders involving abnormal angiogenesis.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: July 8, 2003
    Assignee: Children's Medical Center Corporation
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Troponin subunit I fragment and homologs thereof
    Patent number: 6586401
    Abstract: The present invention relates to a peptide corresponding to human troponin subunit fragment I amino acid residues 118-137 and homologs thereof, as well as pharmaceutical compositions.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: July 1, 2003
    Assignees: Children's Medical Center Corporation, Boston Life Sciences, Inc.
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Pharmaceutical compositions comprising fragments and homologs of troponin subunits
    Publication number: 20030083255
    Abstract: The present invention relates to pharmaceutical compositions comprising therapeutically effective amounts of troponin C, I or T subunits, fragments or homologs for the treatment of diseases or disorders involving abnormal angiogenesis and methods of use thereof.
    Type: Application
    Filed: July 9, 2002
    Publication date: May 1, 2003
    Applicant: Boston Life Sciences, Inc.
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Pharmaceutical compositions comprising troponin subunits, fragments and homologs thereof and methods of their use to inhibit angiogenesis
    Patent number: 6465431
    Abstract: The present invention relates to pharmaceutical compositions comprising therapeutically effective amounts of troponin C, I or T subunits, fragments, or homologs thereof, for the treatment of diseases or disorders involving abnormal angiogenesis and methods of use thereof.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: October 15, 2002
    Assignees: Boston Life Sciences, Inc., Children's Medical Center Corporation
    Inventors: Richard M. Thorn, Marc E. Lanser, Marsha A. Moses, Dmitri G. Wiederschain
  • Peptides for the diagnosis of HTLV-III antibodies, their preparation and use
    Patent number: 4753873
    Abstract: Certain peptide fragments of the human T-cell leukemia (lymphotropic) virus (HTLV-III) are particularly immunoreactive to HTLV-III antibodies, and can therefore be applied to immunodiagnostic tests for the detection of antibodies to HTLV-III.
    Type: Grant
    Filed: February 3, 1986
    Date of Patent: June 28, 1988
    Assignee: Cambridge Bioscience Corporation
    Inventors: Gerald A. Beltz, Richard M. Thorn, Dante J. Marciani, Chung-Ho Hung, William A. Haseltine