Abstract: A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space.

Abstract: A locking device for restricting access to a hatch of a pressure vessel, and, more specifically, a locking device that is responsive to the internal pressure in the pressure vessel so as to minimize the ability of one to open the hatch while the vessel is still pressurized. In some embodiments, the locking device comprises first and second portions of the locking device configurable between an open and a closed configuration and a pressure-responsive locking member in fluid communication with an outlet port of the pressure vessel and arranged to automatically retain the first and second portions in the closed configuration when the pressure inside of the pressure vessel is above a predetermined threshold, wherein in the closed configuration the first and second portions restrict manipulation of the hatch and/or a locking mechanism of the hatch.

Abstract: A system includes a motion sensor system configured for deployment in a cab of a vehicle and to generate substantially in real-time a digital mapping of driver movement during operation of the vehicle. A computer is configured for deployment in the cab and coupled to the motion sensor system. A driver behavior detector is coupled to the computer and configured to detect a driver distraction event using the driver movement mapping. A communication device at the vehicle is configured to communicate an alert message to one or both of a user interface device in the cab and a remote system in response to the detected driver distraction event.

Abstract: The present disclosure provides a locking device for restricting access to a hatch of a pressure vessel, and, more specifically, a locking device that is responsive to the internal pressure in the pressure vessel so as to minimize the ability of one to open the hatch while the vessel is still pressurized. In some embodiments, the locking device comprises first and second portions of the locking device configurable between an open and a closed configuration and a pressure-responsive locking member in fluid communication with an outlet port of the pressure vessel and arranged to automatically retain the first and second portions in the closed configuration when the pressure inside of the pressure vessel is above a predetermined threshold, wherein in the closed configuration the first and second portions restrict manipulation of the hatch and/or a locking mechanism of the hatch.

Abstract: The present disclosure provides a locking device for restricting access to a hatch of a pressure vessel, and, more specifically, a locking device that is responsive to the internal pressure in the pressure vessel so as to minimize the ability of one to open the hatch while the vessel is still pressurized. In some embodiments, the locking device comprises first and second portions of the locking device configurable between an open and a closed configuration and a pressure-responsive locking member in fluid communication with an outlet port of the pressure vessel and arranged to automatically retain the first and second portions in the closed configuration when the pressure inside of the pressure vessel is above a predetermined threshold, wherein in the closed configuration the first and second portions restrict manipulation of the hatch and/or a locking mechanism of the hatch.

Abstract: A system for system for controlling functions of a multi-feed blasting apparatus is disclosed. Tank pressure, charge/discharge control, status of a vessel cover, total hours of pressurization or operation for the vessel and individual feed lines, ambient environmental or weather conditions, and abrasive material level inside the vessel may also be monitored and controlled by the disclosed system.

Abstract: The present disclosure provides a locking device for restricting access to a hatch of a pressure vessel, and, more specifically, a locking device that is responsive to the internal pressure in the pressure vessel so as to minimize the ability of one to open the hatch while the vessel is still pressurized. In some embodiments, the locking device comprises first and second portions of the locking device configurable between an open and a closed configuration and a pressure-responsive locking member in fluid communication with an outlet port of the pressure vessel and arranged to automatically retain the first and second portions in the closed configuration when the pressure inside of the pressure vessel is above a predetermined threshold, wherein in the closed configuration the first and second portions restrict manipulation of the hatch and/or a locking mechanism of the hatch.

Abstract: A set of orthodontic brackets is constructed according to preferred parameters of a Deviation Index in order to provide an orthodontic brace that facilitates movement of teeth to ideal positions. The brace also helps eliminate the need to manually bend the archwire during the final stages of treatment such that chair time is reduced.

Abstract: The present invention is based, at least in part on the discovery of therapeutic agents capable of preventing, inhibiting or modulating abnormal processing, misfolding or aggregation of protein. The therapeutic agents of the invention may prevent, inhibit or modulate the formation of inclusions. The therapeutic agents of the invention may also be capable of facilitating clearance and/or blocking the cellular toxicity of inclusions to treat or ameliorate disorders characterized by protein aggregation. Compounds which bind to structural motifs commonly found in protein aggregates, such as ?-sheets, would represent strong candidates for such compounds and are therefore desirable.