Abstract: A cardiomyocyte maturation medium comprises a base medium, one or more fatty acids such as palmitic acid, glucose and albumin. The one or more fatty acids and glucose are ideally present at a concentration ratio of about 1:10. Typically, the medium does not comprise TGF or insulin, or comprises minimal TGF and/or insulin. A cell culture vessel is provided that comprises opposed poles that facilitate force measurements of developing cardiac muscle.

Abstract: Techniques for generating application interfaces based on semantic-level data are described herein. Application developers may semantically define an application flow. Based on the definition, a system may identify a template of a multipage navigable interface that is compatible with the flow. If multiple templates are compatible, then a template may be recommended or automatically selected based on the semantic information provided by the developer. The system may generate, based on the template and the semantic definition, a multipage navigable interface. The template may encapsulate some design and functional elements in a manner that is independent of the semantic definition.

Abstract: Techniques for component-based software engineering, and more particularly, to techniques for enhancing component based development systems by making components self-aware with respect to the applications that they may be consumed in or other peer components within the applications. An exemplary technique includes determining an addition of one or more components to an interface of an application; identifying an asset definition within metadata of a component of the one or more components added to the interface of the application, where the asset definition provides self-wiring or self-configuring instructions for an asset that needs to be created for the component within a predefined scope when the component is added to the interface; and creating the asset for the component based on the asset definition.

Abstract: Provided herein are in vitro and in vivo methods of inducing cardiomyocyte proliferation by contacting cardiomyocytes with or administering to a subject an effective amount of an agent capable of activating sterol biosynthesis, such as mevalonate biosynthesis. Methods and compositions for regenerating a cardiac tissue in a subject that include administering thereto a therapeutically effective amount of an agent capable of activating sterol biosynthesis in a cardiomyocyte are also provided herein.

Abstract: Techniques for generating application interfaces based on semantic-level data are described herein. Application developers may semantically define an application flow. Based on the definition, a system may identify a template of a multipage navigable interface that is compatible with the flow. If multiple templates are compatible, then a template may be recommended or automatically selected based on the semantic information provided by the developer. The system may generate, based on the template and the semantic definition, a multipage navigable interface. The template may encapsulate some design and functional elements in a manner that is independent of the semantic definition.

Abstract: There is provided an integrity monitor for a display system, the display system comprising an image source and a display. The integrity monitor comprises a controller configured to analyse sensed characteristics at one or more predetermined positions in an image area of the display system and to relate the sensed characteristics to predetermined characteristics of a stimulus, when injected into the system, thereby to determine the presence of a fault in the system. The sensed characteristics may be sensed optically or non-optically. The stimulus may be optical or non-optical.

Abstract: Techniques are provided for encapsulating a user experience design for user interfaces of an application, where the user experience design comprises a look and feel of the application and a plurality of functional elements of the application. A plurality of rules for implementing the one or more user interfaces may be defined, and the rules may be based at least in part on the user experience design. Additionally, a pattern may be generated based at least in part on the plurality of rules. The pattern may be deployed to a distributed network of computing devices, and reused in the design of multiple other applications. The new user interfaces for those applications may be generated based at least in part on the pattern, where the additional applications comply with the look and feel and the plurality of functional elements of the other applications that share the pattern.

Abstract: A refuelling system is disclosed having a fuel conduit, a variable-position valve for controlling a rate of flow of fuel leaving the conduit, and a controller. The controller is configured to receive from a sensor arrangement a measurement of an electrostatic condition in a fuel tank being fuelled by the system. The controller is configured to control the variable-position valve to control the rate of flow of fuel based at least in part on the measurement received from the sensor arrangement.

Abstract: Apparatus for determining respiratory information about a user, the apparatus comprising: a. a plurality of temperature sensors, each temperature sensor having a field of view, the temperature sensors being arranged to detect a temperature gradient within volume of interest and each providing an output signal; b. a support frame having a head on which said temperature sensors are mounted, the support frame and temperature sensors making no contact, in use, with the user; and c. a processor for processing one or more of said output signals to determine said respiratory information about the user.

Abstract: Techniques for component-based software engineering, and more particularly, to techniques for enhancing component based development systems by making components self-aware with respect to the applications that they may be consumed in or other peer components within the applications. An exemplary technique includes determining an addition of one or more components to an interface of an application; identifying an asset definition within metadata of a component of the one or more components added to the interface of the application, where the asset definition provides self-wiring or self-configuring instructions for an asset that needs to be created for the component within a predefined scope when the component is added to the interface; and creating the asset for the component based on the asset definition.

Abstract: Techniques for component-based software engineering, and more particularly, to techniques for enhancing component based development systems by making components self-aware with respect to the applications that they may be consumed in or other peer components within the applications. An exemplary technique includes determining an addition of one or more components to an interface of an application; identifying an asset definition within metadata of a component of the one or more components added to the interface of the application, where the asset definition provides self-wiring or self-configuring instructions for an asset that needs to be created for the component within a predefined scope when the component is added to the interface; and creating the asset for the component based on the asset definition.

Abstract: Systems and methods are provided for managing and tracking process pipelines and other flows in a way that reduces the requirement for a central controlling process to manage every step of the associated pipeline flow and the state associated with each running instance. Job information and pipeline state are tracked by each worker involved in the pipeline. This enables some key capabilities within these process pipelines such as dynamic process re-writing and cross security domain job execution.

Abstract: There is provided an integrity monitor for a display system, the display system comprising an image source and a display. The integrity monitor comprises a controller configured to analyse sensed characteristics at one or more predetermined positions in an image area of the display system and to relate the sensed characteristics to predetermined characteristics of a stimulus, when injected into the system, thereby to determine the presence of a fault in the system. The sensed characteristics may be sensed optically or non-optically. The stimulus may be optical or non-optical.

Abstract: Embodiments of the present invention provide a ring for sensing one or more physiological and/or behavioural parameters of a user. The ring comprises an aperture for receiving a finger of the use. The aperture comprises a sensing portion, one or more sensing means disposed in the sensing portion and a resiliently deformable pad opposing the sensing portion. The resiliently deformable pad is arranged to contact a finger to pressure the finger against the one or more sensing means when the finger is received in the aperture. Aspects of the invention relate to a trigger device, to an apparatus for inducing sleep and to a kit.

Abstract: Techniques for component-based software engineering, and more particularly, to techniques for enhancing component based development systems by making components self-aware with respect to the applications that they may be consumed in or other peer components within the applications. An exemplary technique includes determining an addition of one or more components to an interface of an application; identifying an asset definition within metadata of a component of the one or more components added to the interface of the application, where the asset definition provides self-wiring or self-configuring instructions for an asset that needs to be created for the component within a predefined scope when the component is added to the interface; and creating the asset for the component based on the asset definition.

Abstract: A refuelling system is disclosed having a fuel conduit, a variable-position valve for controlling a rate of flow of fuel leaving the conduit, and a controller. The controller is configured to receive from a sensor arrangement a measurement of an electrostatic condition in a fuel tank being fuelled by the system. The controller is configured to control the variable-position valve to control the rate of flow of fuel based at least in part on the measurement received from the sensor arrangement.

Abstract: Systems and methods are provided for managing and tracking process pipelines and other flows in a way that reduces the requirement for a central controlling process to manage every step of the associated pipeline flow and the state associated with each running instance. Job information and pipeline state are tracked by each worker involved in the pipeline. This enables some key capabilities within these process pipelines such as dynamic process re-writing and cross security domain job execution.

Abstract: Techniques are provided for encapsulating a user experience design for user interfaces of an application, where the user experience design comprises a look and feel of the application and a plurality of functional elements of the application. A plurality of rules for implementing the one or more user interfaces may be defined, and the rules may be based at least in part on the user experience design. Additionally, a pattern may be generated based at least in part on the plurality of rules. The pattern may be deployed to a distributed network of computing devices, and reused in the design of multiple other applications. The new user interfaces for those applications may be generated based at least in part on the pattern, where the additional applications comply with the look and feel and the plurality of functional elements of the other applications that share the pattern.

Abstract: Systems and methods are provided for managing and tracking process pipelines and other flows in a way that reduces the requirement for a central controlling process to manage every step of the associated pipeline flow and the state associated with each running instance. Job information and pipeline state are tracked by each worker involved in the pipeline. This enables some key capabilities within these process pipelines such as dynamic process re-writing and cross security domain job execution.

Abstract: Techniques are provided for encapsulating a user experience design for user interfaces of an application, where the user experience design comprises a look and feel of the application and a plurality of functional elements of the application. A plurality of rules for implementing the one or more user interfaces may be defined, and the rules may be based at least in part on the user experience design. Additionally, a pattern may be generated based at least in part on the plurality of rules. The pattern may be deployed to a distributed network of computing devices, and reused in the design of multiple other applications. The new user interfaces for those applications may be generated based at least in part on the pattern, where the additional applications comply with the look and feel and the plurality of functional elements of the other applications that share the pattern.