Patents by Inventor Richard P. Pioch

Richard P. Pioch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
    Patent number: 5026707
    Abstract: This invention provides ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes which are selective inhibitors of serotonin reuptake.
    Type: Grant
    Filed: January 16, 1990
    Date of Patent: June 25, 1991
    Assignee: Eli Lilly and Company
    Inventors: James A. Nixon, Richard P. Pioch, John M. Schaus, Robert D. Titus
  • N-thiazolylmethylthioalkyl-N-alkyl-amidines and related compounds
    Patent number: 4760075
    Abstract: N-alkyl-N'-(2-aminomethyl-4-thiazolylmethylthio)alkyl guanidines, thioureas, ethenediamines and related compounds, H.sub.2 -receptor antagonists, useful in inhibiting gastric acid secretion in mammals.
    Type: Grant
    Filed: December 23, 1985
    Date of Patent: July 26, 1988
    Assignee: Eli Lilly and Company
    Inventor: Richard P. Pioch
  • Aromastase inhibiting .alpha.,.alpha.-diarylimidazole-4(5)-propionitriles, .alpha.,.alpha.-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles
    Patent number: 4605661
    Abstract: This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain imidazole derivatives. Pharmaceutical formulations of the imidazole derivatives and certain imidazoles are also provided.
    Type: Grant
    Filed: June 18, 1984
    Date of Patent: August 12, 1986
    Assignee: Eli Lilly and Company
    Inventors: Kenneth S. Hirsch, Richard P. Pioch
  • N-Thiazolylmethylthioalkyl-N.sup.1 -alkenyl (or alkynyl)guanidines and related compounds
    Patent number: 4474794
    Abstract: N-alkenyl (or N-alkynyl)-N'-[2-(aminoalkyl)-4-thiazolylmethylthio]alkylguanidines, thioureas, ethenediamines and related compounds, H.sub.2 receptor antagonists, useful in inhibiting gastric acid secretion in mammals.
    Type: Grant
    Filed: March 19, 1982
    Date of Patent: October 2, 1984
    Assignee: Eli Lilly and Company
    Inventor: Richard P. Pioch
  • 2-[2-(2-Aminoalkyl-4-thiazolylmethylthio)alkyl]-amino-5-substituted-4-pyr imidones
    Patent number: 4468399
    Abstract: 2-[2-(2-aminoalkyl-4-thiazolylmethylthio)-alkylene]amino-5-aromatic-substit uted alkylene-4-pyrimidones and related compounds, H.sub.2 receptor antagonists, useful in inhibiting gastric acid secretion in mammals.
    Type: Grant
    Filed: July 20, 1983
    Date of Patent: August 28, 1984
    Assignee: Eli Lilly and Company
    Inventor: Richard P. Pioch
  • N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds
    Patent number: 4382090
    Abstract: N-alkyl-N'-(2-aminoalkyl-4-thiazolylmethylthio)alkyl guanidines, thioureas, ethenediamines and related compounds, H.sub.2 -receptor antagonists, useful in inhibiting gastric acid secretion in mammals.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: May 3, 1983
    Assignee: Eli Lilly and Company
    Inventor: Richard P. Pioch
  • N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
    Patent number: 4375547
    Abstract: N-Alkyl-N'-([2-(aminoalkyl)-4-thiazolylmethyl]thioalkyl) guanidines, thioureas, ethenediamines and related compounds, H.sub.2 receptor antagonists, useful in inhibiting gastric acid secretion in mammals.
    Type: Grant
    Filed: October 2, 1980
    Date of Patent: March 1, 1983
    Assignee: Eli Lilly and Company
    Inventor: Richard P. Pioch
  • 3-(Imidazol-4-yl)-2-phenylpropanenitriles
    Patent number: 4281141
    Abstract: 3-(Imidazol-4-yl)-2-phenylpropanenitriles are useful for control of powdery mildew of cultivated plants.
    Type: Grant
    Filed: May 30, 1980
    Date of Patent: July 28, 1981
    Assignee: Eli Lilly and Company
    Inventors: Leander Merritt, Richard P. Pioch
  • 5-Halo-4-oxo-2-phenylpentanenitriles
    Patent number: 4264521
    Abstract: A series of 5-halo-4-oxo-2-phenylpentanenitriles are useful as intermediates for preparing 3-(imidazol-4-yl)-2-phenylpropanenitriles, which are useful as fungicides.
    Type: Grant
    Filed: May 30, 1980
    Date of Patent: April 28, 1981
    Assignee: Eli Lilly and Company
    Inventor: Richard P. Pioch
  • 3-Phenacylpiperidines
    Patent number: 3962257
    Abstract: 3-Phenacylpiperidines, useful as depressants, stimulants, and anti-inflammatory agents, are obtained by preparing, from a 3-halomethylpiperidine, a 3-piperidylmethylmagnesium halide which is condensed with a benzonitrile.
    Type: Grant
    Filed: May 31, 1974
    Date of Patent: June 8, 1976
    Assignee: Eli Lilly and Company
    Inventors: Richard P. Pioch, Klaus K. Schmiegel