Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: A modular rotary metering unit comprising: a housing having at least one liquid inlet and liquid outlet; a rotatable member arranged to rotate about a longitudinal axis thereof with respect to the housing; and at least one bore passing through the rotatable member, the or each bore having two opposing ends and a shuttle element received therein, the shuttle element being movable between two terminal positions, each towards a respective end of the bore, wherein, when the rotatable member rotates, each bore moves in communication with a liquid inlet of the housing and a liquid outlet of the housing such that liquid can be received from the liquid inlet by the bore at the one end of the bore and the shuttle element can eject liquid from the other end of the bore to the liquid outlet, wherein respective first and second engagement elements are provided at first and second ends of the unit, each of the engagement elements being rotationally linked to the rotatable member.

Abstract: Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.

Abstract: Disclosed is a device and method for obtaining and utilizing data. A handheld device which is capable of optically scanning or receiving RFID signals from an object, storing the data in an internal memory, and then re-transmitting the data is disclosed. The re-transmitted data may trigger access to an internet web site or other database which provides a user with detailed information relating to the scanned object. The device is also usable as a re-configurable electronic key or may be built into electronic devices to allow reconfiguration by scanning a symbol.

Abstract: A metering device of the type in which a shuttle moves axially within a chamber between two terminal positions, with the chamber having fluid inlet and outlet at each end so that fluid may enter through one end to move the shuttle to cause fluid to be ejected through the other end, and vice versa. A control valve is provided to control the fluid flow, the control valve being a spool valve having a spool sealingly slidable within a bore, the spool valve being associated with a device to drive the spool between two alternate positions in response to the shuttle reaching each end of the chamber.

Abstract: A metering device that includes a housing defining a cylindrical chamber containing a reciprocating shuttle. The two opposed end parts of the chamber are interconnected by fluid flow ducts to a cylindrical valve bore. Contained with the valve is a rotary valve rod driven rotationally by a stepping motor. The valve rod has part cut away to form channels or recesses. In one rotational position of the valve rod a flow path is established from an inlet to one end of the chamber and a separate flow path is established from the other end of the chamber to an outlet. In an alternate orientation of the valve rod a flow path is formed from the inlet to the other end of the chamber and the first end of the chamber is connected to an outlet.

Abstract: Information for configuring control apparatus for a power system including a plurality of controlled power supplies is produced using a graphical interface which displays the topology and sequencing of the power supplies in the power system. A database is used to select power supplies to add in determining the power system topology. Sequencing is represented by displacing icons representing the power supplies along lines representing their input and output voltages, and arrows representing startup sequence dependencies. A processor produces the configuration information, consistent with the displayed topology and sequencing, using information for the selected power supplies from the database, for downloading to the control apparatus.

Abstract: A metering device that includes a housing defining a cylindrical chamber containing a reciprocating shuttle. The two opposed end parts of the chamber are interconnected by fluid flow ducts to a cylindrical valve bore. Contained with the valve is a rotary valve rod driven rotationally by a stepping motor. The valve rod has part cut away to form channels or recesses. In one rotational position of the valve rod a flow path is established from an inlet to one end of the chamber and a separate flow path is established from the other end of the chamber to an outlet. In an alternate orientation of the valve rod a flow path is formed from the inlet to the other end of the chamber and the first end of the chamber is connected to an outlet.

Abstract: A system and method of modelling interaction between a plurality of agents and an environment, comprising providing agents with simple characteristics and storing those characteristis, storing detailed information on the complete environment and allowing the agents to access environment information from the stored detailed information on a location by location basis and use the information to progress through the environment, such that a processor can monitor these movements to determine suitability of the environment by providing an underlying environment map which is highly detailed and which is accessible by the simple agents. A more efficient and user friendly system and method for evaluating environment layouts is provided.

Abstract: A metering device contains a rotor which defines elongate chamber, there being a shuttle contained within the chamber movable between two terminal end positions. Frusto-conical surfaces defined on the rotor cooperate with annular members defining corresponding seats. One passage extends from one end of the chamber to one frusto-conical surface, and another passage extends from the other end of the chamber to the other frusto-conical surface. Each annual element defines a respective inlet and outlet for fluid and a shuttle is present within the chamber. As the rotor rotates, the shuttle effects a shuttling movement thus measuring dispensed volumes of fluid. A sensor is provided to detect physical contact of the shuttle with the end of the chamber to cause the rotor to advance.

Abstract: (−)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one, its pharmaceutically acceptable derivatives, pharmaceutical formulation thereof, methods for its preparation and its uses as an antiviral agent are described

Abstract: Disclosed is a device and method for obtaining and utilizing data. A handheld device which is capable of optically scanning or receiving RFID signals from an object, storing the data in an internal memory, and then re-transmitting the data is disclosed. The re-transmitted data may trigger access to an internet web site or other database which provides a user with detailed information relating to the scanned object. The device is also usable as a re-configurable electronic key or may be built into electronic devices to allow reconfiguration by scanning a symbol.

Abstract: (−)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one, its pharmaceutically acceptable derivatives, pharmaceutical formulation thereof, methods for its preparation and its uses as an antiviral agent are described.

Abstract: A plurality of scan lines is used to detect characteristic features of a checkerboard structure or similar pattern structure of symbology within a field of view. The scan lines cross leading edges of the symbology which provides signals to a plurality of processors. The processors detect instances wherein sequential leading edges exhibit angular shifts corresponding to a pattern of the symbology. A further processor is used to detect when a coincidence of these angular shifts occur, thereby providing an indication of the location of the symbology within the field of view.