Abstract: A surgical instrument includes an anvil and an elongate channel. The elongate channel includes a plurality of first electrical contacts and a plurality of electrical connectors comprising a plurality of second electrical contacts, wherein the electrical connectors are spring-biased such that a gap is maintained between the first electrical contacts and the second electrical contacts. The surgical instrument further includes a staple cartridge releasably attachable to the elongate channel, wherein the staple cartridge has a cartridge body comprising a plurality of staple cavities, a plurality of staples deployable from the staple cavities into the tissue, and a plurality of third electrical contacts, wherein the attachment of the staple cartridge to the elongate channel moves the electrical connectors causing the second electrical contacts to bridge the gap and become electrically coupled to the first electrical contacts.

Abstract: The present invention provides methods to treat mood disorders and anxiety disorders using antagonists of the P2X7 receptor and pharmaceutical compositions thereof, or combinations.

Abstract: The present invention provides methods to treat mood disorders and anxiety disorders using antagonists of the P2X7 receptor and pharmaceutical compositions thereof, or combinations.

Abstract: Charge generation layers and charge transport layers which are prepared by coating a substrate with a coating solution prepared by mixing:(A) a binder;(B) a charge generation material or a charge transport material; and(C) an organosilanc of the formula:R.sub.x Si(OR').sub.4-xwherein:R is ##STR1## R' is H- or C.sub.1-4 -alkyl; and x is an integer of 1 to 3,in a suitable solvent, exhibit enhanced adhesion to the substrate, and organic photoconductive imaging receptors which contain such a charge generation layer and/or charge transport layer exhibit improved lifetimes.

Abstract: 4-Quinolinecarboxylic acids and derivatives thereof, such as 2-(2'-fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinolinecarboxylic acid, are useful as immunomodulatory and anti-inflammatory agents. Pharmaceutical formulations containing such compounds are useful for the treatment of autoimmune diseases, organ transplantation rejection, graft vs. host disease, multiple sclerosis, and chronic inflammatory diseases such as rheumatoid arthritis.

Abstract: Phenylquinolinecarboxylic acids and derivatives thereof, such as 2-(2'-Fluoro-1,1'-biphenyl-4-yl)-6-fluoro-3-methyl-4-quinolinecarboxylic acid, or a sodium or potassium salt thereof, are useful for the treatment of skin and muco-epithelial diseases.

Abstract: Antiinflammatory carbinoloimidazoles are provided which have the formula: ##STR1## or a pharmaceutically acceptable salt thereof, whereinR.sup.1 and R.sup.2 independently are H, F, Cl, Br, CH.sub.3, CF.sub.3 or S(O).sub.n R.sup.3 where n is 0, 1 or 2 andR.sup.3 is alkyl of 1-4 carbon atoms;R.sup.4 is H or alkyl of 1-4 carbon atoms with the proviso that R.sup.4 is H when m is 2 or 3; andm is 1 to 3.The carbinoloimidazoles are preferably administered as topical antiinflammatory compositions.