Abstract: The present invention provides the use of all-trans retinoic acid for the production of a pharmaceutical composition for the treatment of acute myeloid leukemia, which use is characterized in that the patients are selected from the group of non-M3 acute myeloid leukemia patients according to a physiologic concentration, e.g. a level of MN1 below a certain critical level analysed in total blood cells, preferably analysed in bone marrow cells. The critical level of MN1 can be determined according to known methods, e.g. by specific determination of the presence of MN1, e.g. using specific anti-MN1 antibody, e.g. in an ELISA or in another immuno specific assay. Preferably, the level of MN1 is determined at its transcription level, e.g. as the concentration of mRNA encoding MN1.

Abstract: The present invention provides the use of all-trans retinoic acid for the production of a pharmaceutical composition for the treatment of acute myeloid leukemia, which use is characterized in that the patients are selected from the group of non-M3 acute myeloid leukemia patients according to a physiologic concentration, e.g. a level of MN1 below a certain critical level analysed in total blood cells, preferably analysed in bone marrow cells. The critical level of MN1 can be determined according to known methods, e.g. by specific determination of the presence of MN1, e.g. using specific anti-MN1 antibody, e.g. in an ELISA or in another immuno specific assay. Preferably, the level of MN1 is determined at its transcription level, e.g. as the concentration of mRNA encoding MN1.

Abstract: A tailpiece has been provided that includes a tubular member, a washing machine connector, and a dryer drainage connector. The washing machine connector can receive a fluid discharge from a washing machine drain line and the dryer drainage connector can receive a fluid discharge from a dryer drain line. In some configurations, the tailpiece include ports. The ports have a plug positioned within them when they are not being utilized and a connector positioned within them when they are being utilized. Additionally, a method of installing a tailpiece beneath a sink has been provided.

Abstract: A tailpiece has been provided that includes a tubular member, a washing machine connector, and a dryer drainage connector. The washing machine connector can receive a fluid discharge from a washing machine drain line and the dryer drainage connector can receive a fluid discharge from a dryer drain line. In some configurations, the tailpiece include ports. The ports have a plug positioned within them when they are not being utilized and a connector positioned within them when they are being utilized. Additionally, a method of installing a tailpiece beneath a sink has been provided.