Abstract: The present invention relates to a method of increasing the sensitivity of a hyperinsulinemic patient to the anti-obesity and antidiabetic effects of a ? adrenergic receptor (? AR) agonist. The method comprises administering to the patient the ? AR agonist and an agent that reduces plasma insulin levels and thereby increases the sensitivity of the patient to the effects of the ? AR agonist.

Abstract: The present invention relates to a method of increasing the sensitivity of a hyperinsulinemic patient to the anti-obesity and antidiabetic effects of a ? adrenergic receptor (?AR) agonist. The method comprises administering to the patient the ?AR agonist and an agent that reduces plasma insulin levels and thereby increases the sensitivity of the patient to the effects of the ?AR agonist.

Abstract: A patient apparatus is configured to receive and analyze information regarding patient compliance with anticoagulation medication and self-test coagulation regimens related to anticoagulation therapy. In addition, a patient apparatus is configured to receive data from a patient, including physiological data, pathophysiological data, biological data, psychological data, neuropsychological data, and/or behavioral data. Utilizing the received patient data, a patient apparatus can modify a warfarin regimen using an algorithm contained within the apparatus. The apparatus can communicate the modified warfarin regimen to the patient and to third parties, such as remotely located healthcare providers. In addition, the apparatus can prompt a patient when to perform a self-test and can prompt a patient to seek immediate medical attention, or to directly contact medical help, when so warranted.