Patents by Inventor Richard W. Burg

Richard W. Burg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antifungal substances and process for their production
    Patent number: 5130445
    Abstract: There is disclosed a series of macrolides isolated from the fermentation broth of a microorganism identified as MA-5000 which morphological analysis reveals to be a strain of Streptomyces hygroscopicus. The compounds structures are presented based upon analytical studies. The compounds have antifungal activity.
    Type: Grant
    Filed: February 25, 1991
    Date of Patent: July 14, 1992
    Assignee: Merck & Co., Inc.
    Inventors: Richard W. Burg, Jerrold M. Liesch, Otto D. Hensens, Sebastian Hernandez
  • Novel antifungal substances and process for their production
    Patent number: 5028537
    Abstract: There is disclosed a series of macrolides isolated from the fermentation broth of a microorganism identified as MA-5000 which morphological analysis reveals to be a strain of Streptomyces hygroscopicus. The compounds' structures are present based upon analytical studies. The compounds have antifungal activity.
    Type: Grant
    Filed: June 6, 1988
    Date of Patent: July 2, 1991
    Assignee: Merck & Co. Inc.
    Inventors: Richard W. Burg, Otto D. Hensens, Jerrold M. Liesch, Sebastian Hernandez, Lucille J. Cole
  • Anti-inflammatory and antidegenerative compounds isolated from L-681,512
    Patent number: 4871727
    Abstract: There are disclosed anti-inflammatory and antidegenerative compounds which are natural products produced by cultivation of sail microorganism L-681,512 under controlled fermentation conditions.
    Type: Grant
    Filed: December 21, 1987
    Date of Patent: October 3, 1989
    Assignee: Merck & Co, Inc.
    Inventors: Richard W. Burg, Eugene L. Dulaney, Otto D. Hensens, Jerrold M. Liesch, John G. Ondeyka, Carol F. Wichmann
  • Sterol inhibitors of testosterone 5.alpha.-reductase
    Patent number: 4814324
    Abstract: The compounds of Formula I are produced by the aerobic fermentation of a fungus of the genus GLIOCLADIUM, ATCC No. 20826. ##STR1## The compounds of Formula I are inhibitors of testosterone 5.alpha.-reductase and are useful in the treatment and prevention of acne, seborrhea, female hirsutism and benign prostatic hypertrophy.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: March 21, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Robert P. Borris, Richard W. Burg, Otto D. Hensens, Leeyuan Huang, Livia Kelemen, Sagrario Mochales
  • Antifungal substances and process for their production
    Patent number: 4575500
    Abstract: There is disclosed a series of macrolides isolated from the fermentation broth of a microorganism identified as MA-5000 which morphological analysis reveals to be a strain of Streptomyces hygroscopicus. The compound's structure is presented based upon analytical studies. The compound has antifungal activity.
    Type: Grant
    Filed: March 26, 1984
    Date of Patent: March 11, 1986
    Assignee: Merck & Co., Inc.
    Inventors: Richard W. Burg, Lucille J. Cole, Sebastian Hernandez
  • Strain of Streptomyces for producing antiparasitic compounds
    Patent number: 4429042
    Abstract: Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the prevention and cure of parasitic infections.
    Type: Grant
    Filed: December 30, 1981
    Date of Patent: January 31, 1984
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Hyman Wallick, Robert E. Ormond, Thomas W. Miller, Richard W. Burg
  • Novel substances and process for their production
    Patent number: 4310519
    Abstract: Novel compounds are produced by the fermentation of a nutrient medium with the previously undescribed microorganism Streptomyces avermitilis. They may be isolated by solvent extraction and chromatographic fractionation techniques. The compounds, which are described generically as C-076 have significant parasiticidal activity. The compounds may be included in compositions for the oral or parenteral administration to animals for the treatment of parasitic infections.
    Type: Grant
    Filed: September 8, 1978
    Date of Patent: January 12, 1982
    Assignee: Merck & Co., Inc.
    Inventors: George Albers-Schonberg, Hyman Wallick, Robert E. Ormond, Thomas W. Miller, Richard W. Burg