Patents by Inventor Richard Yazbeck
Richard Yazbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240164822Abstract: Systems and methods for treatment of tissue including an expandable member designed to be positioned at a site of interest against tissue to be treated and to accommodate fluid set at a temperature range to affect the tissue at the site of interest; an assembly for directing the fluid set at the temperature range into the expandable member, the assembly having an input to introduce the fluid into the expandable member to circulate substantially along an entire length of the expandable member and an output spatially situated from the input to permit fluid flow to be removed from within the expandable member; and a mechanism designed to direct fluid along the assembly and through the input into the expandable member while simultaneously removing fluid from the expandable member through the output, so as to maintain substantially constant fluid pressure within the expandable member.Type: ApplicationFiled: March 21, 2022Publication date: May 23, 2024Inventors: Lishan Aklog, Brian J. deGuzman, Richard Yazbeck, Michael Boutillette, Jim Pelletier, Liem Vu, Mack Krell, Minh Doung, Gregory Eberl
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Publication number: 20240165385Abstract: An intraosseous port device includes a body having a proximal portion configured and arranged for subcutaneous placement and having a first channel, and a distal portion designed for intraosseous placement at a site of interest and having a second channel in fluid communication with the first channel to define a pathway from the proximal portion to the site of interest, a penetrable seal occluding at least a portion of the first channel, and a retention ring coupled to at least one of the body and the penetrable seal.Type: ApplicationFiled: April 19, 2022Publication date: May 23, 2024Inventors: Lishan Aklog, Brian J. deGuzman, Richard Yazbeck, Michael Boutillette, Taylor Bensel
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Publication number: 20240108805Abstract: Methods and apparatuses for providing an adjustable flow resistor. The adjustable flow resistor can include a chamber into which fluid is introduced, having an input end and an output end. A flow modifier can be situated within the chamber, between the input end and the output end, to modify a flow rate of the fluid. An adjustable resistance member can be positioned to interact with the flow modifier within the chamber to controllably modify the constant flow rate out of the adjustable flow resistor.Type: ApplicationFiled: February 2, 2022Publication date: April 4, 2024Inventors: Lishan Aklog, Richard Yazbeck, Michael Boutillette, Jessie Gifford, Peter Aliski, Amos Cruz, Jonathan O'Keefe
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Publication number: 20240091464Abstract: Systems and methods for exhausting air from a flow pathway are provided. The systems can include a flow resistor having an input coupled to a fluid source and an outlet to output a fluid at an output flow rate, the flow resistor including an adjustable flow channel for modifying the output flow rate of the fluid flowing through the flow resistor; and a priming device having an elongated portion, the elongated portion being substantially rigid axially and configured for insertion through the outlet of the flow resistor to engage the flow resistor and adjust the output flow rate to allow air to be exhausted from the flow pathway through the flow resistor.Type: ApplicationFiled: February 4, 2022Publication date: March 21, 2024Inventors: Lishan Aklog, Richard Yazbeck, Jessie Gifford, Julian Fricks, Peter Aliski
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Publication number: 20240036591Abstract: Systems and methods for managing flow along a pathway are provided herein. The system and method can include a pump for providing a fluid flow along the pathway, a flow regulator in fluid communication at its input end with the pump and designed to maintain flow therethrough at a substantially constant flow rate, and the pathway being in fluid communication with an output of the flow resistor for directing fluid flow to a destination at the substantially constant flow rate.Type: ApplicationFiled: February 4, 2022Publication date: February 1, 2024Inventors: Lishan Aklog, Julian Fricks, Peter Aliski, Richard Yazbeck, Jessie Gifford
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Publication number: 20230349474Abstract: The systems and methods of the present disclosure provides an independent passive variable resistor that can be interposed between a fluid reservoir at an inlet pressure and receptacle at an outlet pressure. The resistor can adjust resistance to the pressure difference from the input to the output so that the flow rate through it is a constant rate. The resistor can include a moveable element and a biasing mechanism located in a chamber to create a flow channel. Each side of the moveable element is exposed to the inlet and outlet pressures and moves within the flow channel to modify the resistance of the flow through the chamber in response to the pressures. The balance of these forces determines the position moveable element, which interacts with the fluid channel to determine the flow resistance through variable resistor. The biasing mechanism can provide the necessary pressure to establish equilibrium flow rate.Type: ApplicationFiled: May 3, 2023Publication date: November 2, 2023Inventors: Lishan Aklog, Richard Yazbeck, Michael Boutillette, Peter Aliski, Jonathan O'Keefe, Amos Cruz
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Patent number: 11668404Abstract: The systems and methods of the present disclosure provides an independent passive variable resistor that can be interposed between a fluid reservoir at an inlet pressure and receptacle at an outlet pressure. The resistor can adjust resistance to the pressure difference from the input to the output so that the flow rate through it is a constant rate. The resistor can include a moveable element and a biasing mechanism located in a chamber to create a flow channel. Each side of the moveable element is exposed to the inlet and outlet pressures and moves within the flow channel to modify the resistance of the flow through the chamber in response to the pressures. The balance of these forces determines the position moveable element, which interacts with the fluid channel to determine the flow resistance through variable resistor. The biasing mechanism can provide the necessary pressure to establish equilibrium flow rate.Type: GrantFiled: April 10, 2020Date of Patent: June 6, 2023Assignee: PAVmed Inc.Inventors: Lishan Aklog, Richard Yazbeck, Michael Boutillette, Peter Aliski, Jonathan O'Keefe, Amos Cruz
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Publication number: 20230000475Abstract: Provided herein are methods and a device for collecting biological samples. In particular, the present disclosure relates to a device designed to specifically capture samples within the target areas of a patient for specific cell collection for particular diagnosis.Type: ApplicationFiled: June 30, 2022Publication date: January 5, 2023Applicant: Case Western Reserve UniversityInventors: Sanford Markowitz, Amitabh Chak, Joseph Willis, Lishan Aklog, Richard Yazbeck, Michael Boutillette, Brian deGuzman, David Wurtman
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Publication number: 20220175221Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the axType: ApplicationFiled: August 3, 2021Publication date: June 9, 2022Inventors: John Frederick Cornhill, Jeffrey Milsom, Sameer Sharma, Tuan Anh Nguyen, Christopher Dillon, Gabriel Greeley, Rahul Sathe, Matthew DeNardo, Ashley Whitney, Jeremy Van Hill, Anthony Assal, Stephen Evans, Timothy Robinson, Alan Fortunate, Audrey Bell, Richard Yazbeck, Brian David Chouinard, Phal kun Chan, William Rebh
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Publication number: 20220054115Abstract: Methods and systems for cell collection. Methods and systems include a collection mechanism being transformable between a collection state having an expanded diameter and a retrieval state where the diameter is less than that of the collection state and a conveyance mechanism having a distal end to which the collection mechanism is attached and designed to place the collection mechanism at a site of interest for cell collection. The Methods and systems also include an activation mechanism to transform the collection mechanism between the collection state and the retrieval state.Type: ApplicationFiled: August 17, 2021Publication date: February 24, 2022Inventors: Lishan Aklog, Brian J. deGuzman, Richard Yazbeck, Michael Boutillette, Jessie Gifford
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Publication number: 20210386410Abstract: A device for collecting a biological sample in a subject, the device including an inflatable portion attached to a tubular member, and designed to expand from within the tubular member when inflated and to retract within the tubular member, a surface on the inflatable portion provided with varied thickness to facilitate movement of the inflatable portion between an expanded state and a retracted state, and a plurality of projections on the surface to allow collection of the biological sample when the inflatable portion is in the expanded state.Type: ApplicationFiled: June 16, 2020Publication date: December 16, 2021Inventors: Amitabh Chak, Sanford Markowitz, Dennis Siedlak, Joseph Willis, Lishan Aklog, Michael Boutillette, Richard Yazbeck
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Publication number: 20210369256Abstract: A method for collecting a cell sample, including eosinophil white blood cells in a patient is provided. The method includes advancing to a location in an esophagus associated with eosinophilic esophagitis (EoE), a device provided with a collection portion having a first axial end portion and an inflatable second axial end portion. Thereafter, axially moving the second axial end portion, relative to the first axial end portion, from a collapsed position within the first axial end portion into an expanded position out from the first axial end portion. Once the second axial end portion is in the expanded position, allowing it to engage the location associated with EoE to collect a sample of cells.Type: ApplicationFiled: May 26, 2021Publication date: December 2, 2021Inventors: Sanford Markowitz, Amitabh Chak, Joseph Willis, Lishan Aklog, Richard Yazbeck, Michael Boutillette, Brian deGuzman, David Wurtman
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Patent number: 11076743Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the axType: GrantFiled: December 11, 2018Date of Patent: August 3, 2021Assignees: Cornell UniversityInventors: John Frederick Cornhill, Jeffrey Milsom, Sameer Sharma, Tuan Anh Nguyen, Christopher Dillon, Gabriel Greeley, Rahul Sathe, Matthew DeNardo, Ashley Whitney, Jeremy Van Hill, Anthony Assal, Stephen Evans, Timothy Robinson, Alan Fortunate, Audrey Bell, Richard Yazbeck, Brian David Chouinard, Phal Kun Chan, William Rebh
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Publication number: 20200360667Abstract: The present invention relates to a catheter construction and method of use suitable for use in navigating within a body lumen or vessel, such as a vein, artery, nasal cavity, esophagus, etc. to assist in the performance of various procedures. The device can include a flexible tubular member having a proximal end, a distal end, and channel extending substantially between the proximal end and the distal end, a stiffening sleeve positioned at the distal end of the tubular member to provide stiffness thereto so that a removable procedural tool can be attached to the tubular member, and an elongated non-elastic tether situated within the channel of the tubular member and secured at one end to the distal end of the member, such that when the tether is held in tension, the tether acts to minimize the tubular member from deviating from a neutral state.Type: ApplicationFiled: May 15, 2020Publication date: November 19, 2020Inventors: Lishan Aklog, Michael Boutillette, Brian deGuzman, Gregory Eberl, Shaun O'Neil, Dennis Siedlak, Richard Yazbeck
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Publication number: 20200325999Abstract: The systems and methods of the present disclosure provides an independent passive variable resistor that can be interposed between a fluid reservoir at an inlet pressure and receptacle at an outlet pressure. The resistor can adjust resistance to the pressure difference from the input to the output so that the flow rate through it is a constant rate. The resistor can include a moveable element and a biasing mechanism located in a chamber to create a flow channel. Each side of the moveable element is exposed to the inlet and outlet pressures and moves within the flow channel to modify the resistance of the flow through the chamber in response to the pressures. The balance of these forces determines the position moveable element, which interacts with the fluid channel to determine the flow resistance through variable resistor. The biasing mechanism can provide the necessary pressure to establish equilibrium flow rate.Type: ApplicationFiled: April 10, 2020Publication date: October 15, 2020Inventors: Lishan Aklog, Richard Yazbeck, Michael Boutillette, Peter Aliski, Jonathan O'Keefe, Amos Cruz
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Publication number: 20190343372Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the axType: ApplicationFiled: December 11, 2018Publication date: November 14, 2019Inventors: John Frederick Cornhill, Jeffrey Milsom, Sameer Sharma, Tuan Anh Nguyen, Christopher Dillon, Gabriel Greeley, Rahul Sathe, Matthew DeNardo, Ashley Whitney, Jeremy Van Hill, Anthony Assal, Stephen Evans, Timothy Robinson, Alan Fortunate, Audrey Bell, Richard Yazbeck, Brian David Chouinard, Phal kun Chan, William Rebh
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Patent number: 10149601Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the axType: GrantFiled: June 3, 2016Date of Patent: December 11, 2018Assignees: Lumendi Ltd., Cornell UniversityInventors: John Frederick Cornhill, Jeffrey Milsom, Sameer Sharma, Tuan Anh Nguyen, Christopher Dillon, Gabriel Greeley, Rahul Sathe, Matthew DeNardo, Ashley Whitney, Jeremy Van Hill, Anthony Assal, Stephen Evans, Timothy Robinson, Alan Fortunate, Audrey Bell, Richard Yazbeck, Brian David Chouinard, Phal kun Chan, William Rebh
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Publication number: 20160278626Abstract: Apparatus comprising: a sleeve adapted to be slid over the exterior of an endoscope; an aft balloon secured to the sleeve; an inflation/deflation tube carried by the sleeve and in fluid communication with the interior of the aft balloon; a pair of hollow push tubes slidably mounted to the sleeve, the pair of hollow push tubes being connected to one another at their distal ends with a raised push tube bridge, the raised push tube bridge being configured to nest an endoscope therein; and a fore balloon secured to the distal ends of the pair of hollow push tubes, the interior of the fore balloon being in fluid communication with the interiors of the pair of hollow push tubes, wherein the fore balloon is capable of assuming a deflated condition and an inflated condition, and further wherein (i) when the fore balloon is in its deflated condition, an axial opening extends therethrough, the axial opening being sized to receive the endoscope therein, and (ii) when the fore balloon is in its inflated condition, the axType: ApplicationFiled: June 3, 2016Publication date: September 29, 2016Inventors: John Frederick Cornhill, Jeffrey Milsom, Sameer Sharma, Tuan Anh Nguyen, Christopher Dillon, Gabriel Greeley, Rahul Sathe, Matthew DeNardo, Ashley Whitney, Jeremy Van Hill, Anthony Assal, Stephen Evans, Timothy Robinson, Alan Fortunate, Audrey Bell, Richard Yazbeck, Brian David Chouinard, Phala Chan, William Rebh