Patents by Inventor Rico Czaja
Rico Czaja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11674129Abstract: The present invention relates to polypeptide, preferably to a glucose isomerase, comprising an amino acid sequence, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, is at least 95% identical to an amino acid sequence of SEQ ID NO:1, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, comprises an amino acid substitution at one or more amino acid positions, wherein the one or more amino acid positions is/are each and independently selected from the group consisting of SEQ ID NO: 1 amino acid positions 89, 90, 95, 0, 33, 34, 35, and 59. The present invention further relates to methods preparing glucose including the use of the polypeptides of the invention for preparing glucose.Type: GrantFiled: June 9, 2021Date of Patent: June 13, 2023Assignees: NEW MATTERHORN, LLC, C-LEcta GmbHInventors: Birgit Brucher, Andreas Vogel, Hanna Maria Dudek, Rico Czaja
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Publication number: 20210317432Abstract: The present invention relates to polypeptide, preferably to a glucose isomerase, comprising an amino acid sequence, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, is at least 95% identical to an amino acid sequence of SEQ ID NO:1, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, comprises an amino acid substitution at one or more amino acid positions, wherein the one or more amino acid positions is/are each and independently selected from the group consisting of SEQ ID NO: 1 amino acid positions 89, 90, 95, 0, 33, 34, 35, and 59. The present invention further relates to methods preparing glucose including the use of the polypeptides of the invention for preparing glucose.Type: ApplicationFiled: June 9, 2021Publication date: October 14, 2021Inventors: Birgit Brucher, Andreas Vogel, Hanna Maria Dudek, Rico Czaja
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Patent number: 11066659Abstract: The present invention relates to polypeptide, preferably to a glucose isomerase, comprising an amino acid sequence, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, is at least 95% identical to an amino acid sequence of SEQ ID NO:1, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, comprises an amino acid substitution at one or more amino acid positions, wherein the one or more amino acid positions is/are each and independently selected from the group consisting of SEQ ID NO: 1 amino acid positions 89, 90, 95, 0, 33, 34, 35, and 59. The present invention further relates to methods preparing glucose including the use of the polypeptides of the invention for preparing glucose.Type: GrantFiled: May 4, 2018Date of Patent: July 20, 2021Assignees: NEW MATTERHORN, LLC, C-LEcta GmbHInventors: Birgit Brucher, Andreas Vogel, Hanna Maria Dudek, Rico Czaja
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Patent number: 10774356Abstract: The invention relates to transaminases and their use. The ATAs according to the invention are particularly useful for catalyzing the conversion of amines to ketones and/or vice versa. Preferably, the transaminase (ATA) according to the invention comprises an amino acid sequence with at least 80% homology to SEQ ID NO:1, wherein the amino acid sequence is engineered compared to SEQ ID NO:1 such that it comprises at least a substitution selected from the group consisting of F255L, F255A, F255C, F255D, F255E, F255G, F255H, F255K, F255M, F255N, F255P, F255Q, F255R, F255S, F255T, F255V, F255W, and F255Y.Type: GrantFiled: June 10, 2016Date of Patent: September 15, 2020Assignee: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Patent number: 10724008Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: GrantFiled: August 30, 2018Date of Patent: July 28, 2020Assignee: C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Publication number: 20200224187Abstract: The present invention relates to polypeptide, preferably to a glucose isomerase, comprising an amino acid sequence, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, is at least 95% identical to an amino acid sequence of SEQ ID NO:1, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, comprises an amino acid substitution at one or more amino acid positions, wherein the one or more amino acid positions is/are each and independently selected from the group consisting of SEQ ID NO: 1 amino acid positions 89, 90, 95, 0, 33, 34, 35, and 59. The present invention further relates to methods preparing glucose including the use of the polypeptides of the invention for preparing glucose.Type: ApplicationFiled: May 4, 2018Publication date: July 16, 2020Inventors: Birgit Brucher, Andreas Vogel, Hanna Maria Dudek, Rico Czaja
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Patent number: 10370693Abstract: The invention relates to transaminases that are particularly useful for catalyzing the conversion of amine substrates to ketone products and/or vice versa.Type: GrantFiled: June 10, 2016Date of Patent: August 6, 2019Assignee: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Publication number: 20190078130Abstract: The invention relates to transaminases and their use. The ATAs according to the invention are particularly useful for catalyzing the conversion of amines to ketones and/or vice versa. Preferably, the transaminase (ATA) according to the invention comprises an amino acid sequence with at least 80% homology to SEQ ID NO:1, wherein the amino acid sequence is engineered compared to SEQ ID NO:1 such that it comprises at least a substitution selected from the group consisting of F255L, F255A, F255C, F255D, F255E, F255G, F255H, F255K, F255M, F255N, F255P, F255Q, F255R, F255S, F255T, F255V, F255W, and F255Y.Type: ApplicationFiled: June 10, 2016Publication date: March 14, 2019Applicant: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Publication number: 20190062714Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: ApplicationFiled: August 30, 2018Publication date: February 28, 2019Applicant: C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Patent number: 10196645Abstract: An expression vector including two separately inducible converging promoters P1 and P2, and expression system including such an expression vector and an additional regulator vector, a method of protein expression using such an expression system, and a method of investigating (meta)genome libraries using such an expression system.Type: GrantFiled: January 11, 2016Date of Patent: February 5, 2019Assignee: c-LEcta GmbHInventors: Thomas Greiner-Stoeffele, Meike Hoffmann, Marc Struhalla, Rico Czaja
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Publication number: 20180298354Abstract: The invention relates to transaminases that are particularly useful for catalyzing the conversion of amine substrates to ketone products and/or vice versa.Type: ApplicationFiled: June 10, 2016Publication date: October 18, 2018Applicant: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Patent number: 10093905Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: GrantFiled: April 17, 2015Date of Patent: October 9, 2018Assignee: C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Publication number: 20170218345Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: ApplicationFiled: April 17, 2015Publication date: August 3, 2017Applicants: C-LEcta GmbH, C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Publication number: 20160194647Abstract: An expression vector including two separately inducible converging promoters P1 and P2, and expression system including such an expression vector and an additional regulator vector, a method of protein expression using such an expression system, and a method of investigating (meta)genome libraries using such an expression system.Type: ApplicationFiled: January 11, 2016Publication date: July 7, 2016Inventors: Thomas Greiner-Stoeffele, Meike Ballschmitter, Marc Struhalla, Rico Czaja
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Publication number: 20120021950Abstract: An expression vector including two separately inducible converging promoters P1 and P2, and expression system including such an expression vector and an additional regulator vector, a method of protein expression using such an expression system, and a method of investigating (meta)genome libraries using such an expression system.Type: ApplicationFiled: June 16, 2011Publication date: January 26, 2012Applicant: C-Iecta GmbHInventors: Thomas GREINER-STOEFFELE, Meike Ballschmitter, Marc Struhalla, Rico Czaja
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Publication number: 20110071067Abstract: The invention relates to washing and cleaning agents comprising a combination of chlorophyllase and a further hydrolase, preferably a lipase, particularly a galactolipase. The combination of chlorophyllase and galactolipase improves the cleaning power, particularly for chlorophyll-containing stains, compared to each of the two enzymes alone.Type: ApplicationFiled: May 12, 2009Publication date: March 24, 2011Applicants: CLARIANT FINANCE (BVI) LIMITED, C-LECTAInventors: Gerd Reinhardt, Hans Juergen Scholz, Rico Czaja, Thomas Greiner-Stoeffele, Marc Struhalla