Abstract: Provided is a modified conjugated diene-based polymer, a rubber composition and a tire with excellent low loss property and durability, and a method of producing a modified conjugated diene-based polymer with which the presently disclosed modified conjugated diene-based polymer can be produced. The modified conjugated diene-based polymer has two or more modifying groups in one modified conjugated diene-based polymer molecule, where the modifying groups between molecules have a non-covalent bond with energy of 10 kJ/mol to 250 kJ/mol. The rubber composition contains the modified conjugated diene-based polymer. The tire uses the rubber composition.

Abstract: Provided is a modified conjugated diene-based polymer, a rubber composition and a tire with excellent low loss property and durability, and a method of producing a modified conjugated diene-based polymer with which the presently disclosed modified conjugated diene-based polymer can be produced. The modified conjugated diene-based polymer has two or more modifying groups in one modified conjugated diene-based polymer molecule, where the modifying groups between molecules have a non-covalent bond with energy of 10 kJ/mol to 250 kJ/mol. The rubber composition contains the modified conjugated diene-based polymer. The tire uses the rubber composition.

Abstract: An object of the present invention is to provide a rubber composition for a tire, which is, when it is used as a rubber composition for a tire, capable of exhibiting good dry grip properties and excellent grip properties in both a relatively low temperature range and a relatively high temperature range, as well as a tire produced by using the rubber composition. The rubber composition of the present invention contains: a rubber component made of at least one type of diene-based polymer; and a copolymer resin obtained by copolymerizing ?-methylstyrene based monomer and aromatic vinyl monomer.

Abstract: An object of the present invention is to provide a rubber composition for a tire, which is, when it is used as a rubber composition for a tire, capable of exhibiting good dry grip properties and excellent grip properties in both a relatively low temperature range and a relatively high temperature range, as well as a tire produced by using the rubber composition. The rubber composition of the present invention contains: a rubber component made of at least one type of diene-based polymer; and a copolymer resin obtained by copolymerizing ?-methylstyrene based monomer and aromatic vinyl monomer.

Abstract: A tissue equivalent for transplantation having a three-dimensional structure which is cultured in vitro, contains cells to be transplanted and which can be transplanted into a living body after the culture, characterized by including a scaffold layer mainly culturing a scaffold constituting the three-dimensional structure and a cell layer which is localized at least in a part of the surface of the tissue equivalent for transplantation continuously with the scaffold layer and which contains the cells to be transplanted or extra cellular matrix in a larger amount than the scaffold layer. This tissue equivalent is appropriately employed as a tissue equivalent for transplantation in a relatively large size. This tissue equivalent enables realization of prompt fixation to the neighborhood of the transplanted tissue and prevention of falling off.

Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.

Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.

Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.

Abstract: A tissue equivalent for transplantation having a three-dimensional structure which is cultured in vitro, contains cells to be transplanted and which can be transplanted into a living body after the culture, characterized by including a scaffold layer mainly culturing a scaffold constituting the three-dimensional structure and a cell layer which is localized at least in a part of the surface of the tissue equivalent for transplantation continuously with the scaffold layer and which contains the cells to be transplanted or extra cellular matrix in a larger amount than the scaffold layer. This tissue equivalent is appropriately employed as a tissue equivalent for transplantation in a relatively large size. This tissue equivalent enables realization of prompt fixation to the neighborhood of the transplanted tissue and prevention of falling off.

Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.

Abstract: To determine the transplant compatibility of an in vitro cultured tissue, a method measures the stiffness of the cultured tissue by using a stiffness measuring device, which stiffness measuring device includes a detecting unit and calculation means, the detecting unit includes a contact unit, a vibrator connected to the contact unit, and a vibration detecting unit for detecting the vibration of the vibrator, and the calculation means determines stiffness information by calculation based on the detected result from the vibration detecting element; and by bringing the contact unit into contact with the cultured tissue. With this method the transplant compatibility of the cultured tissue can be nondestructively and easily determined easily and the quality of the cultured tissue can be appropriately controlled.