Abstract: Disclosed are stable extended release formulations and pharmaceutical compositions of Clozapine that exhibit improved stability under a variety of conditions, as well as processes for the preparation of such formulations and compositions.

Abstract: An extended release pharmaceutical composition of Clozapine The extended release composition of Clozapine provides an extended release pharmaceutical composition having Clozapine, a seal coating, an acidic coating, and an extended release coating. The composition is particularly suitable for dispensing a once-a-day solid oral pharmaceutical formulation which releases a therapeutically effective amount of Clozapine over an extended time period.

Abstract: Disclosed are stable extended release formulations and pharmaceutical compositions of Clozapine that exhibit improved stability under a variety of conditions, as well as processes for the preparation of such formulations and compositions.

Abstract: Disclosed is an extended release pharmaceutical composition of Clozapine, which can be provided as a reservoir type dosage form, and when dosed to a patient once daily achieves at steady state, AUC0-24h, Cmax and Cmin in patient plasma that are within 80 to 125% bioequivalence criteria compared to immediate release Clozapine dosed at the same total daily dose divided twice per day. Further, the pharmaceutical composition of Clozapine can provide once daily dosing regimen in order to improve patient compliance and reduces side effects in patients in need thereof. The pharmaceutical composition further lacks any significant food effect on oral administration.

Abstract: An extended release pharmaceutical composition of Clozapine The extended release composition of Clozapine provides an extended release pharmaceutical composition having Clozapine, a seal coating, an acidic coating, and an extended release coating. The composition is particularly suitable for dispensing a once-a-day solid oral pharmaceutical formulation which releases a therapeutically effective amount of Clozapine over an extended time period.

Abstract: An extended release pharmaceutical composition of Clozapine The extended release composition of Clozapine provides an extended release pharmaceutical composition having Clozapine, a seal coating, an acidic coating, and an extended release coating. The composition is particularly suitable for dispensing a once-a-day solid oral pharmaceutical formulation which releases a therapeutically effective amount of Clozapine over an extended time period.

Abstract: A system for displaying a dashboard display in a vehicle includes a vehicle data bus interface for communicating with vehicle subsystems of a vehicle management system, a dashboard display module, and a dashboard store for storing a dashboard display definition. In one example, the dashboard display module obtains from the vehicle bus information regarding which of the plurality of vehicle subsystems are enabled, and transmits the information regarding which of the plurality of vehicle subsystems are enabled to a device external to the vehicle management system.

Abstract: A system for displaying a dashboard display in a vehicle includes a vehicle data bus interface for communicating with vehicle subsystems of a vehicle management system, a dashboard display module, and a dashboard store for storing a dashboard display definition. In one example, the dashboard display module obtains from the vehicle bus information regarding which of the plurality of vehicle subsystems are enabled, and transmits the information regarding which of the plurality of vehicle subsystems are enabled to a device external to the vehicle management system.

Abstract: According to one example of the present invention, there is provided apparatus for displaying a dashboard display in a vehicle. The apparatus comprises a vehicle data bus interface for communicating with vehicle subsystems of a vehicle management system, a rules store for storing a set of dashboard display rules, and a dashboard display module. The dashboard display module is arranged to obtain a dashboard display definition, to determine whether the dashboard display definition is in compliance with the dashboard display rules; to obtain, where it is so determined, data from one or more of the vehicle subsystems in accordance with the dashboard display definition, and to display the obtained data in accordance with the dashboard display definition.

Abstract: Embodiments of the present invention disclose a system and method for vehicle personalization. According to one embodiment, at least one customizable setting of a plurality of configuration settings associated with the vehicle is determined. Upon receiving a request for personalization of at least one configuration setting, user profile and preference setting information is retrieved. Furthermore, at least one customizable setting of the vehicle is adjusted based on the preference settings of the user profile information.

Abstract: According to one example of the present invention, there is provided apparatus for displaying a dashboard display in a vehicle. The apparatus comprises a vehicle data bus interface for communicating with vehicle subsystems of a vehicle management system, a rules store for storing a set of dashboard display rules, and a dashboard display module. The dashboard display module is arranged to obtain a dashboard display definition, to determine whether the dashboard display definition is in compliance with the dashboard display rules; to obtain, where it is so determined, data from one or more of the vehicle subsystems in accordance with the dashboard display definition, and to display the obtained data in accordance with the dashboard display definition.

Abstract: A method, system, and computer program product for monitoring the response time for a web service provider is provided. In one embodiment, receiving a web service inbound transaction is received at a web service proxy server. The web service proxy server invokes a response time monitoring service and provides the response time monitoring service with a unique transaction identifier for the inbound transaction. The web service proxy server also invokes, on the web service provider, a web service requested by the inbound transaction. The proxy server later receives an outbound transaction from the web service provider corresponding to the original inbound transaction and invokes the response time monitoring service, once again, providing the unique transaction identifier to the response time monitoring service.

Abstract: A system and method of fault management includes receiving a service request, encountering a fault in during the execution of the service request, persisting the fault, and providing a fault response.

Abstract: One aspect of the invention is a transaction processing system comprising a software service operable to receive a transaction request and to generate a first object associated with the transaction request. An object generator may convert the first object into a first document written in a self-describing language. A document generator may convert the first document into a first transaction message according to a schema associated with a first transaction type determinable from the first document.