Patents by Inventor Rita Bernhardt

Rita Bernhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 21-hydroxylation of steroids
    Patent number: 11965199
    Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: April 23, 2024
    Assignee: SANOFI
    Inventors: Claus Lattemann, Thomas Stillger, Bernd Janocha, Hans-Falk Rasser, Sebastian Rissom, Simone Anderko, Rita Bernhardt, Frank Hannemann
  • 21-hydroxylation of steroids
    Patent number: 11608514
    Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.
    Type: Grant
    Filed: June 26, 2019
    Date of Patent: March 21, 2023
    Inventors: Claus Lattemann, Thomas Stillger, Bernd Janocha, Hans-Falk Rasser, Sebastian Rissom, Simone Anderko, Rita Bernhardt, Frank Hannemann
  • 21-Hydroxylation of Steroids
    Publication number: 20220228189
    Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.
    Type: Application
    Filed: January 31, 2022
    Publication date: July 21, 2022
    Inventors: Claus Lattemann, Thomas Stillger, Bernd Janocha, Hans-Falk Rasser, Sebastian Rissom, Simone Anderko, Rita Bernhardt, Frank Hannemann
  • 21-Hydroxylation of Steroids
    Publication number: 20190352690
    Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.
    Type: Application
    Filed: June 26, 2019
    Publication date: November 21, 2019
    Inventors: Claus Lattemann, Thomas Stillger, Bernd Janocha, Hans-Falk Rasser, Sebastian Rissom, Simone Anderko, Rita Bernhardt, Frank Hannemann
  • 21-hydroxylation of steroids
    Patent number: 10385376
    Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: August 20, 2019
    Assignee: SANOFI
    Inventors: Claus Lattemann, Thomas Stillger, Bernd Janocha, Hans-Falk Rasser, Sebastian Rissom, Simone Anderko, Rita Bernhardt, Frank Hannemann
  • Whole-cell system for cytochrome P450 monooxygenases biocatalysis
    Patent number: 10308972
    Abstract: The subject of the present invention is a whole-cell catalysis process for converting substrates of cytochrome P450 monooxygenases of eukaryotic origin into valuable biotechnological products. The subject of the present invention is also microorganisms genetically engineered to achieve those biotransformations with high rates and processes to prepare these microorganism strains.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: June 4, 2019
    Assignee: SANOFI CHIMIE
    Inventors: Adrian Gerber, Frank Hannemann, Sabrina Bleif, Michael Kleser, Rita Bernhardt
  • 21-Hydroxylation of Steroids
    Publication number: 20170321241
    Abstract: Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-hydroxylating enzyme or steroid 21-hydroxylase, expression vectors comprising a nucleic acid encoding for a steroid 21-hydroxylase and a kit for carrying out the method for the 21-hydroxylation of steroids in cells.
    Type: Application
    Filed: October 29, 2015
    Publication date: November 9, 2017
    Inventors: Claus Lattemann, Thomas Stillger, Bernd Janocha, Hans-Falk Rasser, Sebastian Rissom, Simone Anderko, Rita Bernhardt, Frank Hannemann
  • Whole-Cell System For Cytochrome P450 Monooxygenases Biocatalysis
    Publication number: 20160376625
    Abstract: The subject of the present invention is a whole-cell catalysis process for converting substrates of cytochrome P450 monooxygenases of eukaryotic origin into valuable biotechnological products. The subject of the present invention is also microorganisms genetically engineered to achieve those biotransformations with high rates and processes to prepare these microorganism strains.
    Type: Application
    Filed: June 17, 2014
    Publication date: December 29, 2016
    Inventors: Adrian Gerber, Frank Hannemann, Sabrina Bleif, Michael Kleser, Rita Bernhardt
  • SURFACE DISPLAY OF POLYPEPTIDES CONTAINING A METAL PORPHYRIN OR A FLAVIN
    Publication number: 20140011706
    Abstract: The present invention relates to a method for the display of recombinant functional polypeptides containing a prosthetic group selected from metal porphyrin and flavin containing groups on the surface of a host cell using the transporter domain of an autotransporter.
    Type: Application
    Filed: September 22, 2011
    Publication date: January 9, 2014
    Applicant: Autodisplay Biotech GMBH
    Inventors: Stephanie Schumacher, Rita Bernhardt, Frank Hannemann, Joachim Jose
  • Selective inhibitors of human corticosteroid syntheses
    Publication number: 20090105278
    Abstract: The invention relates to compounds for selectively inhibiting human corticosteroid syntheses CYP11B1 and CYP11B2, to the production thereof and to their use for treating hypercortisolism and diabetes mellitus or insufficiency of the heart and myocardial fibrosis.
    Type: Application
    Filed: July 21, 2005
    Publication date: April 23, 2009
    Applicant: Universitat Des Saarlandes
    Inventors: Rolf Hartmann, Sarah Ulmschneider, Ursula Muller-Viera, Rita Bernhardt, Mattas Bureik
  • Functional surface display of polypeptides
    Publication number: 20040259151
    Abstract: The present invention relates to a method for the display of recombinant functional polypeptides containing a prosthetic group and/or plurality of subunits on the surface of a host cell using the transporter domain of an autotransporter.
    Type: Application
    Filed: September 2, 2003
    Publication date: December 23, 2004
    Inventors: Joachim Jose, Frank Hannemann, Rita Bernhardt