Abstract: An embodiment is a catheter comprising a first elongate shaft having a proximal end, a distal end and a first lumen therethrough, a wire having a proximal end and a distal end at least partially disposed in the first elongate shaft, the distal end extending distally from the first elongate shaft, and a motion control apparatus connected to the proximal end of the wire, further comprising a device attached to the distal end of the wire for changing the shape of an embolus, wherein the device is configured to change the shape of the embolus to unclog a distal catheter lumen.

Abstract: Device and methods for removing a foreign object from a body lumen are disclosed. A retrieval device in accordance with an exemplary embodiment of the present invention may include an elongated member including a flexible collector element, and a core wire that can be engaged by the physician to actuate the collector element between a first position and a second position with the body. The collector element may comprise a coiled section including a coiled flat ribbon adapted to assume a substantially straight shape in the first position and an expanded shape forming one or more helically oriented loops in the second position. The collector element may also comprise one or more fibers operatively coupled to the coiled section.

Abstract: An embodiment is a catheter comprising a first elongate shaft having a proximal end, a distal end and a first lumen therethrough, a wire having a proximal end and a distal end at least partially disposed in the first elongate shaft, the distal end extending distally from the first elongate shaft, and a motion control apparatus connected to the proximal end of the wire, further comprising a device attached to the distal end of the wire for changing the shape of an embolus, wherein the device is configured to change the shape of the embolus to unclog a distal catheter lumen.

Abstract: Device and methods for removing a foreign object from a body lumen are disclosed. A retrieval device in accordance with an exemplary embodiment of the present invention may include an elongated member including a flexible collector element, and a core wire that can be engaged by the physician to actuate the collector element between a first position and a second position with the body. The collector element may comprise a coiled section including a coiled flat ribbon adapted to assume a substantially straight shape in the first position and an expanded shape forming one or more helically oriented loops in the second position. In other embodiments, the collector element may comprise a filter basket including a plurality of filter struts adapted to expand in the second position.

Abstract: A catheter loop manager apparatus which controls the slack portion of a catheter located adjacent to an implanted pump and prevents fibrotic encapsulation of the slack catheter portion. The catheter loop manager comprises a retainer element configured to associate with an implantable pump and to releasibly hold or retain a loop or section of catheter adjacent to the pump. A pull tool is used to releasibly engage a catheter section and pull the catheter section into a loop within a retention channel in retainer element.

Abstract: An embodiment is a catheter comprising a first elongate shaft having a proximal end, a distal end and a first lumen therethrough, a wire having a proximal end and a distal end at least partially disposed in the first elongate shaft, the distal end extending distally from the first elongate shaft, and a motion control apparatus connected to the proximal end of the wire, further comprising a device attached to the distal end of the wire for changing the shape of an embolus, wherein the device is configured to change the shape of the embolus to unclog a distal catheter lumen.

Abstract: A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The drug is combined with the carrier without the need for using organic solvents or melting temperatures (fusion) through the use of a transition compound such as polyethylene glycol which partially solubilizes the drug and/or plasticizes the polymer.

Abstract: A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The drug is combined with the carrier without the need for using organic solvents or melting temperatures (fusion) through the use of a transition compound such as polyethylene glycol which partially solubilizes the drug and/or plasticizes the polymer.

Abstract: A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The drug is combined with the carrier without the need for using organic solvents or melting temperatures (fusion) through the use of a transition compound such as polyethylene glycol which partially solubilizes the drug and/or plasticizes the polymer.