Patents by Inventor Roa Pu Claire Shen

Roa Pu Claire Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND RECOMBINANT POLYPEPTIDE FOR INCREASING PRODUCTION OF INDIGOID COMPOUND
    Publication number: 20230279367
    Abstract: The present disclosure provides a method for increasing production of an indigoid compound, including the following steps: (a) mutating a wild-type flavin-containing monooxygenase to a mutant flavin-containing monooxygenase expressed in Escherichia coli; and (b) culturing the Escherichia coli in a bacterial culture medium comprising tryptophan to allow the mutant FMO to interact with tryptophan for a predetermined time to convert the tryptophan into the indigoid compound. Compared to the wild-type flavin-containing monooxygenase, the mutant flavin-containing monooxygenase increases production of the indigoid compound. The present disclosure also provides a recombinant polypeptide for increasing production of the indigoid compound.
    Type: Application
    Filed: December 7, 2022
    Publication date: September 7, 2023
    Inventors: Roa-Pu Claire Shen, Zi-Yi Yang, Vincent Ruan, Pi-Ju Yang
  • Biofuel production by recombinant microorganisms
    Patent number: 9416378
    Abstract: Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: August 16, 2016
    Assignee: The Regents of the University of California
    Inventors: James C. Liao, Shota Atsumi, Kevin M. Smith, Roa Pu Claire Shen, Anthony F. Cann, Michael R. Connor
  • BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS
    Publication number: 20150376656
    Abstract: Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.
    Type: Application
    Filed: March 3, 2015
    Publication date: December 31, 2015
    Inventors: James C. Liao, Shota Atsumi, Kevin M. Smith, Roa Pu Claire Shen, Anthony F. Cann, Michael R. Connor
  • Biofuel production by recombinant microorganisms
    Patent number: 8975049
    Abstract: Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: March 10, 2015
    Assignee: The Regents of the University of California
    Inventors: James C. Liao, Shota Atsumi, Kevin M. Smith, Roa Pu Claire Shen, Anthony F. Cann, Michael R. Connor
  • BUTANOL PRODUCTION BY RECOMBINANT MICROORGANISMS
    Publication number: 20090111154
    Abstract: Provided are microorganisms that catalyze the synthesis of biofuels from a suitable substrate such as glucose. Also provided are methods of generating such organisms and methods of synthesizing biofuels using such organisms. Provided are microorganisms comprising non-naturally occurring metabolic pathway for the production of higher alcohols.
    Type: Application
    Filed: April 3, 2008
    Publication date: April 30, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: James C. Liao, Shota Atsumi, Mark P. Brynildsen, Anthony F. Cann, Katherine J. Chou, Roa Pu Claire Shen, Kevin M. Smith, Taizo Hanai, Michael R. Connor
  • BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS
    Publication number: 20090081746
    Abstract: Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.
    Type: Application
    Filed: February 8, 2008
    Publication date: March 26, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: James C. Liao, Shota Atsumi, Kevin M. Smith, Roa Pu Claire Shen, Anthony F. Cann, Michael R. Connor