Patents by Inventor Robert A. Murgita

Robert A. Murgita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT HUMAN ALPHA-FETOPROTEIN AS AN IMMUNOSUPPRESSIVE AGENT
    Publication number: 20090053254
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Application
    Filed: February 25, 2008
    Publication date: February 26, 2009
    Applicant: Merrimack Pharmaceuticals, Inc.
    Inventor: Robert A. Murgita
  • Recombinant human alpha-fetoprotein as an immunosuppressive agent
    Patent number: 7423024
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Grant
    Filed: May 4, 2004
    Date of Patent: September 9, 2008
    Assignee: Merrimack Pharmaceuticals, Inc.
    Inventor: Robert A. Murgita
  • Recombinant human alpha-fetoprotein as a cell proliferative agent
    Patent number: 7101837
    Abstract: A method of promoting bone marrow cell proliferation in a mammal by administering unglycosylated recombinant human alpha-fetoprotein is disclosed.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: September 5, 2006
    Assignee: Martinex R & D Inc.
    Inventor: Robert A. Murgita
  • Use of rAFP inhibit or prevent apoptosis
    Publication number: 20050203023
    Abstract: A method of inhibiting apoptosis in a cell by administering to the cell an apoptosis inhibiting amount of recombinant human alpha-feta protein or an apoptosis-inhibiting fragment thereof.
    Type: Application
    Filed: May 2, 2005
    Publication date: September 15, 2005
    Inventors: Robert Murgita, Robert Mulroy, Stace Lindsay
  • Recombinant human alpha-fetoprotein as an immunosuppressive agent
    Publication number: 20050026815
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Application
    Filed: May 4, 2004
    Publication date: February 3, 2005
    Inventor: Robert Murgita
  • Recombinant human alpha-fetoprotein as an immunosuppressive agent
    Patent number: 6774108
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: August 10, 2004
    Assignee: Martinex R & D Inc.
    Inventor: Robert A. Murgita
  • RECOMBINANT HUMAN ALPHA-FETOPROTEIN AS AN IMMUNOSUPPRESSIVE AGENT
    Publication number: 20040092437
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Application
    Filed: August 27, 2001
    Publication date: May 13, 2004
    Inventor: Robert A. Murgita
  • Recombinant alpha-fetoprotein for treating cancers
    Patent number: 6630445
    Abstract: Disclosed is a method of inhibiting a neoplasm in a mammal, the method includes administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: October 7, 2003
    Assignee: Martinex R & D, Inc.
    Inventor: Robert A. Murgita
  • Recombinant human alpha-fetoprotein as a cell proliferative agent
    Patent number: 6627440
    Abstract: Disclosed is a cell culture medium including recombinant human alpha-fetoprotein or a cell-stimulating fragment or analog thereof.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: September 30, 2003
    Assignee: Martinex R & D Inc.
    Inventor: Robert A. Murgita
  • Recombinant alpha-fetoprotein hybrid cytotoxins for treating and diagnosing cancers
    Patent number: 6534479
    Abstract: Disclosed is a method of inhibiting a neoplasm in a mammal, the method includes administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein.
    Type: Grant
    Filed: December 3, 1996
    Date of Patent: March 18, 2003
    Assignee: Martinex R & D Inc.
    Inventor: Robert A. Murgita
  • Recombinant human alpha-fetoprotein as an immunosuppressive agent
    Publication number: 20020193297
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Application
    Filed: August 27, 2001
    Publication date: December 19, 2002
    Inventor: Robert A. Murgita
  • Recombinant alpha-fetoprotein for treating cancers
    Publication number: 20020155996
    Abstract: Disclosed is a method of inhibiting a neoplasm in a mammal, the method includes administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein.
    Type: Application
    Filed: April 4, 2002
    Publication date: October 24, 2002
    Inventor: Robert A. Murgita
  • Recombinant alpha-fetoprotein for treating and diagnosing cancers
    Patent number: 6416734
    Abstract: Disclosed is a method of inhibiting a neoplasm in a mammal, the method includes administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: July 9, 2002
    Assignee: Martinex R&D Inc.
    Inventor: Robert A. Murgita
  • Expression and purification of cloned human alpha-fetoprotein
    Patent number: 6331611
    Abstract: Disclosed is substantially pure recombinant human alpha-fetoprotein produced using prokayote and insect cells.
    Type: Grant
    Filed: July 21, 1995
    Date of Patent: December 18, 2001
    Assignee: McGill University
    Inventor: Robert A. Murgita
  • Recombinant human alpha-fetoprotein as an immunosuppressive agent
    Patent number: 6288034
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: September 11, 2001
    Assignee: Martinex R & D Inc.
    Inventor: Robert A. Murgita
  • Recombinant human alph-fetoprotein as an immunosuppressive agent
    Patent number: 5965528
    Abstract: Disclosed are methods of inhibiting autoreactive immune cell proliferation in a mammal, involving administering to the mammal a therapeutically effective amount of recombinant human alpha-fetoprotein or an immune cell anti-proliferative fragment or analog thereof.
    Type: Grant
    Filed: January 24, 1995
    Date of Patent: October 12, 1999
    Assignee: McGill University
    Inventor: Robert A. Murgita
  • Expression and purification of cloned alpha-fetoprotein
    Patent number: 5384250
    Abstract: In general, the invention features a method for producing human alpha-fetoprotein in prokaryctic cells. The method includes: providing a transformed prokaryotic cell including a recombinant DNA molecule encoding human alpha-fetoprotein operably linked to sequence elements capable of directing expression of alpha-fetoprotein, and permitting the transformed cell to express human alpha-fetoprotein.
    Type: Grant
    Filed: October 8, 1993
    Date of Patent: January 24, 1995
    Assignee: McGill University
    Inventor: Robert A. Murgita