Abstract: A system of multi-modal transmission of packetized data in a voice activated data packet based computer network environment is provided. A natural language processor component can parse an input audio signal to identify a request and a trigger keyword. Based on the input audio signal, a direct action application programming interface can generate a first action data structure, and a content selector component can select a content item. An interface management component can identify first and second candidate interfaces, and respective resource utilization values. The interface management component can select, based on the resource utilization values, the first candidate interface to present the content item. The interface management component can provide the first action data structure to the client computing device for rendering as audio output, and can transmit the content item converted for a first modality to deliver the content item for rendering from the selected interface.

Abstract: An apparatus for hot drape forming a part includes a plurality of pyrometers, a bladder covering a formable material, and a pyrometer control medium positioned between the plurality of pyrometers and the formable material. The plurality of pyrometers are configured to measure a temperature of the pyrometer control medium.

Abstract: The present disclosure is directed to new materials, to processes, products, and apparatus for controlling the production of new materials with enhanced properties. Processing, including layering, Nano-infusion, and other methods for combining spider silk proteins with ceramics, metals, graphene, and/or other stiff materials is now feasible using current technologies to provide new materials and/or products with enhanced and controlled properties. Products may be fabricated to control the flexibility of ceramics, metals, graphene, or other materials to specifications not previously attainable based on the presence of proteins, such as man-made spider silk proteins or webbing.

Abstract: An apparatus for hot drape forming a part includes a plurality of pyrometers, a bladder covering a formable material, and a pyrometer control medium positioned between the plurality of pyrometers and the formable material. The plurality of pyrometers are configured to measure a temperature of the pyrometer control medium.

Abstract: An apparatus for hot drape forming a part includes a plurality of pyrometers, a bladder covering a formable material, and a pyrometer control medium positioned between the plurality of pyrometers and the formable material. The plurality of pyrometers are configured to measure a temperature of the pyrometer control medium.

Abstract: The present disclosure provides a method for treating a patient having cancer, such as glioblastoma. The method may comprise obtaining a biological sample from the patient, and detecting a mutation in a microtubule-related gene is present in the biological sample. The method further comprises administering an effective amount of a pharmaceutical composition comprising a tubulin polymerization inhibitor, such as an auristatin, to the patient.

Abstract: An apparatus for hot drape forming a part includes a plurality of pyrometers, a bladder covering a formable material, and a pyrometer control medium positioned between the plurality of pyrometers and the formable material. The plurality of pyrometers are configured to measure a temperature of the pyrometer control medium.

Abstract: A method of manufacturing a composite panel is described. The method includes pre-stabilizing a honeycomb core with at least one layer of a pre-stabilizing material, surrounding the honeycomb core with at least one composite laminate skin layer, and curing the at least one composite laminate skin layer.

Abstract: Polynucleotides are provided which are useful as amplification primers and hybridization probes for detecting BS106 target sequence in a test sample. The primers and probes can be employed in amplification based methods for detecting the presence of BS106 sequences in a test sample. Additionally, the primers and probes can be used to perform homogeneous, real time reverse-transcriptase polymerase chain reaction to detect BS106 target sequence in a test sample.

Abstract: A method of manufacturing a composite panel is described. The method includes pre-stabilizing a honeycomb core with at least one layer of a pre-stabilizing material, surrounding the honeycomb core with at least one composite laminate skin layer, and curing the at least one composite laminate skin layer.

Abstract: A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as BS106 and transcribed from breast tissue is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast such as breast cancer. Also provided are antibodies which specifically bind to BS106-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BS106 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.

Abstract: A modular electronic device where (predominantly) sealed modules are aligned and attached/connected in pre-determined sequences, forming a robust block-like structure with extendable function: Control and/or inter-module communication are implemented without direct electrical interconnect, by non-contact means such as (magnetic, inductive, light, infrared, radio frequency, sound, ultrasound, or other non-contact means). This device's inter-module power transfer may be with or without direct electrical contact, or devices may be internally powered. Power transfer through inductive/transformer action where one or more alignment pins are used as transformer core is one potential implementation. Modules may be liquid filled to facilitate cooling and/or crush resistance to high-pressure environments.

Abstract: A digital data encryption methodology that uses truly random data rather than pseudo-random data generated by conventional binary computer algorithms to encrypt and decode computer data is made by converting a natural source of random data from its native analog domain to digital through an Analog to Digital converter creating a set of random encryption “keys”. Once a truly random source is recorded in a digital format it may be distributed to a set of trusted devices for use in encoding or decoding data sent to or received from compatible trusted devices. In order for compatible devices to communicate a decoding device would have to start decoding in-phase with the data as encoded by the device that sent the data. The encryption can be further enhanced by varying the access sequence of the recorded keys used for encryption and required for decryption: i.e.: sequence patterns could vary base on patterns that only 2 devices know of, or could be based on time or other pre-determined sequences.

Abstract: A modular electronic device where (predominantly) sealed modules are aligned and attached/connected in pre-determined sequences, forming a robust block-like structure with extendable function: Control and/or inter-module communication are implemented without direct electrical interconnect, by non-contact means such as (magnetic, inductive, light, infrared, radio frequency, sound, ultrasound, or other non-contact means). This device's inter-module power transfer may be with or without direct electrical contact, or devices may be internally powered. Power transfer through inductive/transformer action where one or more alignment pins are used as transformer core is one potential implementation. Modules may be fluid filled to facilitate cooling and/or crush resistance to high-pressure environments.

Abstract: An electronic component or assembly that is assembled within a case that is designed to operate as a liquid phase to gas phase heat pipe where said electronic component or assembly is introduced into a liquid or partially liquid partially gaseous environment; whereby said liquid evaporates into a gas absorbing heat energy and transferring it to and through the component's or assembly's case. The case will be engineered out of materials that do not contaminate the liquid and electronics with ions and will be engineered to operate in any physical orientation.

Abstract: A 3 dimensional electronic assembly comprised of a series or plurality of electronic Flex circuit sub-assemblies that form a layered Flex circuit assembly. Each Flex circuit sub-assembly is electronically connected to one or more other Flex circuits forming a multi-layer electronic Flex circuit assembly where various layers are separated by a substance that is designed to transfer heat away from the electronic components with the intent of cooling the electronic devices contained within the assembly. Each said Flex circuit sub-assembly/layer contains one or more trace layers for the conduction of electronic signals, power, and ground. Each Flex circuit layer may also contain electronic components such that the overall device forms an electronic assembly with embedded electronic components. A layered Flex circuit assembly will contain at least two Flex circuit sub-assemblies to which electronic components are electrically attached forming a 3 dimensional electronic assembly.

Abstract: Novel lactones of polysaccharide carboxylic acids, and methods for the preparation of a variety of conjugates therefrom, as well as the novel conjugates, are provided. Conjugates include metallo-coordinated cisplatin (and carboplatin), as well as conjugates of ellipticinium, aminoglutethimide, mitoxantrone, mitoguazone, cis 3-hexen-1-ol, and other nucleophilic biologically effective agents. Also provided are conjugates via a coupling agent of biologically effective agents, such as Vitamin E, DTPA, TAXOL and TAXOTERE.

Abstract: A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS198 and transcribed from GI tract tissue, is described. These sequences are useful for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS198-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS198 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

Abstract: Polynucleotides are provided which are useful as amplification primers and hybridization probes for detecting BS106 target sequence in a test sample. The primers and probes can be employed in amplification based methods for detecting the presence of BS106 sequences in a test sample. Additionally, the primers and probes can be used to perform homogeneous, real time reverse-transcriptase polymerase chain reaction to detect BS106 target sequence in a test sample.

Abstract: Data security has two facets, protecting/saving a person's/business's data or destroying data so that it cannot fall into the wrong hands. This invention relates to mechanisms & methodologies for injecting a gas, liquid, solid, chemical, biological agent, nano-technology, or other substance into an existing disk drive for the purpose of protecting &/or destroying the disks, heads, and/or enclosure. A dry inert gas will help protect disk drive heads/media and provides a way to extend the disk drives altitude operational characteristics, substances have been developed that can destroy disk media, & other substances may be used that can make data contained on the disk media difficult or impossible. Thus methods for injecting or introducing various substances into the enclosure of a disk drive are a significant aspect of data security.