Abstract: A device for the destruction of biohazardous waste converts harmful waste products into environmentally friendly discharge in compliance with environmental protection agency (EPA) standards. The device includes a waste disposal chamber where a crucible resides. The crucible contains a basket for holding the waste which is heated through induction coils that surround the crucible. The waste is vaporized and ionized in a vacuum forming a waste gas and drawn through a catalytic converter and a hot plasma jet via vacuum suction. The waste gas is then exhausted via a discharge duct where is it condensed by a heat exchanger further refining the waste gas into environmentally friendly molecules such as carbon dioxide. The waste destruction device further includes a programmable logic controller and user interface to control the device. Once the waste destruction process is completed, a compressor passes compressed air over the crucible to rapidly cool the crucible.

Abstract: Drop-to-drop connection schemes are described for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly.

Abstract: A perfusion manifold assembly is described that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate. A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body.

Abstract: The disclosure provides apparatus and methods of use pertaining to a bidirectional biomechanical prosthetic finger assembly. In one embodiment, the assembly includes an eccentric metacarpophalangeal (MCP) pivot configured for swivelable attachment to a hand of a user, a distal coupler, and an articulation assembly rotatively coupled therebetween. A ring configured to receive a user's residual finger is disposed upon the articulation assembly, and may be adjusted to a target location based on a length of the residual finger. The articulation assembly is configured to utilize vertical movements of the residual finger within the ring to articulate the distal coupler within a plane parallel to an x-z plane, and the MCP pivot is configured to utilize lateral movements of the residual finger within the ring to articulate the distal coupler within a plane parallel to an x-y plane. Other embodiments are also disclosed.

Abstract: The disclosure provides apparatus and methods of use pertaining to a biomechanical finger brace assembly. In one embodiment, the assembly includes a coupling tip, a proximal ring configured to concentrically receive a user's finger, a distal ring configured to concentrically receive the finger, and a rocker formed in an H-shape. The distal ring and the rocker are pivotally suspended between a proximal coordinated pivot point anchored on the proximal ring and a distal coordinated pivot point anchored on the coupling tip, such that movements of the finger within the proximal ring articulate the distal ring together with the rocker to articulate the coupling tip. The coupling tip may include an open end or an enclosed recess to accept a minimally-amputated or non-amputated finger. Other embodiments are also disclosed.

Abstract: The present invention relates to an improved system and method for the assembly and installation of pipeline. In accordance with aspects of the invention, the pipeline is assembled at one or more assembly sites located at a particular location of a pipeline route. The pipeline is pulled out of the assembly site and along a trench using a transport unit, such as a winch. The trench may contain a plurality of conveyance units, such as rollers, over which the pipeline is conveyed. The pipeline may continue to be pulled through the trench as portions of the pipeline are assembled at the assembly site, and the pipeline may be pulled until the pipeline has reached a desired location within the trench.

Abstract: The disclosure provides apparatus and methods of use pertaining to a bidirectional biomechanical prosthetic finger assembly. In one embodiment, the assembly includes an eccentric metacarpophalangeal (MCP) pivot configured for swivelable attachment to a hand of a user, a distal coupler, and an articulation assembly rotatively coupled therebetween. A ring configured to receive a user's residual finger is disposed upon the articulation assembly, and may be adjusted to a target location based on a length of the residual finger. The articulation assembly is configured to utilize vertical movements of the residual finger within the ring to articulate the distal coupler within a plane parallel to an x-z plane, and the MCP pivot is configured to utilize lateral movements of the residual finger within the ring to articulate the distal coupler within a plane parallel to an x-y plane. Other embodiments are also disclosed.

Abstract: A transmitter for measuring a process pressure includes a pressure sensor and a temperature sensor providing an input temperature signal. A first remote pressure sensitive diaphragm couples to the transmitter by a first capillary tube filled with a fill fluid having a density as a function of fill fluid temperature. An input circuit is operably connected to at least the pressure sensor and provides an intermediate pressure signal at least roughly representative of the process pressure. A correcting circuit is coupled to the temperature sensor and to the input circuit. The correcting circuit processes the intermediate pressure signal by compensating for the fill fluid density as a function of the temperature and provides a compensated output more closely representative of the process pressure. The correction circuit further performs an initial height determination based upon a pressure measurement made while no pressure is applied to the first diaphragm.

Abstract: A system, method and apparatus for a transit seating system including multiple seat frames, each seat frame including, at least one forward support and at least one rearward support. The at least one forward support and the at least one rearward support are capable of being detachably secured to a transit vehicle floor. A seat back height track system is vertically and slideably coupled to the seat frame. A seat back subframe is coupled to the seat back height track system. A seat base frame is coupled to the seat back height track system through a seat hinge. The at least one forward support is capable of overlapping the at least one rearward support when at least two of the seat frames are in a nested or fully compressed or stowed configuration.

Abstract: Methods, systems, and media for presenting caption information based on volume setting adjustments are provided.

Abstract: The disclosure provides apparatus and methods of use pertaining to a prosthetic finger assembly. In one embodiment, the assembly includes a coupling tip and a distal ring coupled with the coupling tip. The assembly further includes a proximal ring coupled with the distal ring. A rocker formed in an H-shape with a first end forming a first split prong and a second end forming a second split prong may extend between the coupling tip and the proximal ring. The coupling tip, distal ring, proximal ring, and H-shaped rocker may all be hingedly connected such that movements of the residual finger within the proximal ring articulate the distal ring together with the rocker to articulate the coupling tip. Other embodiments are also disclosed.

Abstract: Some embodiments include a microalgae culturing system including a bioreactor adapted to propagate microalgae in a culture solution using in combination at least one of natural and artificial light, and at least one nutrient including at least a carbon source, where the microalgae are freely suspended in and form part of the culture solution. A microalgae feed source is coupled to the bioreactor and a first controller between a water conditioning assembly and the bioreactor. The water conditioning assembly is coupled as an input of supply water to the bioreactor, and configured to condition the supply water to a specified purity that enables substantially unhindered growth of the microalgae in the culture solution to a specified concentration, and the first controller is configured to control supply of the microalgae feed source to the bioreactor.

Abstract: A device for the destruction of biohazardous converts harmful waste products into environmentally friendly discharge in compliance with environmental protection agency (EPA) standards. The device includes a waste disposal chamber where a crucible resides. The crucible contains a basket for holding the waste which is heated through induction coils that surround the crucible. The waste is vaporized and ionized in a vacuum forming a waste gas and drawn through a catalytic converter and a hot plasma jet via vacuum suction. The waste gas is then exhausted via a discharge duct where is it condensed by a heat exchanger further refining the waste gas into environmentally friendly molecules such as carbon dioxide. The waste destruction device further includes a programmable logic controller and user interface to control the device.

Abstract: The disclosure provides apparatus and methods of use pertaining to a prosthetic finger assembly. In one embodiment, the assembly includes a coupling tip and a distal ring coupled with the coupling tip. The assembly further includes a proximal ring coupled with the distal ring. A rocker formed in an H-shape with a first end forming a first split prong and a second end forming a second split prong may extend between the coupling tip and the proximal ring. The coupling tip, distal ring, proximal ring, and H-shaped rocker may all be hingedly connected such that movements of the residual finger within the proximal ring articulate the distal ring together with the rocker to articulate the coupling tip. Other embodiments are also disclosed.

Abstract: A perfusion manifold assembly is described that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate. A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body.

Abstract: The present invention provides a method of treating a disease associated with elevated KRAS activity or expression in a subject, comprising suppressing KRAS expression in the subject by targeting an expression regulatory region of KRAS gene using a CRISPR-Guide Nucleotide Directed Modulation (GNDM). Also, provided is a CRISPR-GNDM system for suppressing KRAS expression comprising (a) a protein selected from the group consisting of dCas9 or dCpf1, a fusion protein of dCas9 or dCpf1 and Kruppel associated box (KRAB), and (b) a guide nucleotide targeting an expression regulatory region of KRAS gene.

Abstract: An aircraft wing (1) has a wing tip device (3) joined thereto. The root (7) of the wing tip device (3) is joined to the tip of the wing (1) at a first connection (11). An external strut (9) extends between the wing (1) and the wing tip device (3), the strut (9) being joined to the wing (1) at a second connection (13). The second connection (13) is inboard of the first connection, such that loadings on the wing tip device (3) generated during use, are transferred, via the strut (9), to a location on the wing (1) that is inboard of where the root (7) of the wing tip device (3) is joined to the tip of the wing.

Abstract: An adhesive and release liner application system and method. A bottom table is slidable with respect to a frame and a middle table is slidable with respect to the bottom table. An elevator drive subsystem between a top table and the middle table is configured to adjust the elevation of the top table relative to the middle table. An adhesive head, connected to an adhesive supply subsystem, a release liner applicator, a release liner cutter, and a staple gun are mounted to the top table for applying the adhesive to a surface of a structural member positioned adjacent the top table, for applying a release liner over the adhesive on the surface, for inserting at least one staple through the release liner and into the surface, and for cutting the release liner.