Abstract: Anti-tumor activity in humans can be augmented by administering to the mammalian host a pharmacologically effective amount of mammalian IL-2 and at least one immunotoxin that binds selectively to human tumor cells. The IL-2 and immunotoxin are preferably administered separately to the host. The composition is useful for prophylactic or therapeutic treatment of such cancers as ovarian and breast cancer.

Abstract: Anti-tumor activity in mammals can be augmented by administering to the mammalian host a synergistically effective amount of TNF and IL-2 or of TNF and IFN-.beta., or of TNF, IL-2 and IFN-.beta. in combination. The composition of TNF and IL-2 and/or IFN-.beta. may be prepared in vitro or administered separately to the host. If the TNF and IL-2 are administered sequentially, the TNF must be administered prior to the IL-2 to obtain synergy. The composition is useful for treating such cancers as mastocytoma, melanoma, leukemia, lymphoma, mammary adenocarcinoma, and pharyngeal squamous cell carcinoma.

Abstract: A seed drill including depending furrow openers having a lower shovel and a supporting seed boot. Each seed boot is pivotally supported on a longitudinal drag bar assembly connected to it about a transverse pivotal connection. The forwardly extending arm at the upper end of the seed boot selectively engages one end of a longitudinal leaf spring mounted to the drag arm assembly. A preselected planting position for the shovel and seed boot is defined by an overlying adjustable stop. An arcuate abutment surface is interposed between the seed boot arm and leaf spring. A stop is interposed between the drag arm assembly and leaf spring for limiting upward movement of the free spring end.

Abstract: A press wheel improvement for seed drills in which one or more open recesses are presented through the circular rim of the press wheel to form transverse dams along packed furrow walls. The recesses are bounded by walls that present a projecting tab extended beyond the conical wheel surfaces. A complementary insert can be fastened to each tab when damming of the furrows is not desired or required by field conditions. The tabs cooperate with straw walkers to assist in clearing trash and preventing obstruction of the straw walkers by rocks wedged between them and the conical press wheel walls.

Abstract: The absence of a wire (40) in proper position under the bonding tool (32) of an ultrasonic wire bonder is detected by energizing the bonder transducer (14) while the wire is pulled to break it after the second bond (B) has been made. The pulling of the wire to break it changes the transducer impedance, which is monitored to signal presence or absence of a wire in its proper location.

Abstract: A method and apparatus for determining optical power attenuation across a splice between first and second optical fibers utilizes the algorithm:dB=10 log (1-L.sub.tel) (2)where L.sub.tel is determined by compensating for differences in intensity profiles existant in the first optical fiber when injecting light therein for purposes of measuring attenuation versus the intensity profile created when injecting light into the first fiber for transmitting telecommunications data and the light has been propagating in the fiber for a distance and steady state intensity distribution is achieved. Preferably, a numerical aperture of the first optical fiber and a sample optical fiber are empirically determined, and L.sub.tel is calculated by compensating for differences between these numerical apertures.

Abstract: This invention provides a method and apparatus for making certain measurements across a splice of a first optical fiber and a second optical fiber, then calculating the actual decibel attenuation across the splice for optical signals transmitted through the fibers during actual use. The method of this invention involves measuring the optical power P.sub.2 in the second fiber with the fiber ends separated longitudinally a certain distance, then measuring the optical power P.sub.1 in the second fiber with the fiber ends positioned close together for effecting the splice. The attenuation is calculated from the formuladB=10 log(P.sub.1 /RP.sub.2)where R is a predetermined constant for the fibers being spliced.

Abstract: A system adapted for the application of a moisture-proof barrier to a substrate. The system comprises a liquid rubber precursor formulation and an isocyanate formulation which are adapted for mixing to provide a reactive mixture for application to the substrate. The liquid rubber precursor includes a hydroxyl terminated butadiene polymer, a polyether triol, an organo-mercury catalyst, carbon black, a low oil absorbency silica, a suspending agent for the silica, a molecular sieve dessicant, a limited proportion of an organic solvent, and lecithin in an amount sufficient to provide a formulation viscosity of not greater than about 20,000 cps at 27.degree. C. The second formulation contains a urethane prepolymer derived from a polypropylene glycol ether polyol and toluene diisocyanate, containing between about 13 and about 17% by weight free isocyanate groups.