Abstract: The use of two mercury and arsenic removal media: A) a sulfur-impregnated organoclay; and B) a coupling agent-reacted organoclay, wherein the coupling agent preferably contains a mercapto, disulfide, tretrasulfide and/or polysulfide end group provides mercury removal media having increased reactivity, stability, and synergistic mercury removal ability. The preferred mercury removal media described herein is prepared by reacting an organophilic clay containing onium ions A) with elemental sulfur; and B) with a sulfur-containing coupling agent, preferably containing a mercapto, disulfide, tetrasulfide, and/or polysulfide moiety.

Abstract: The use of a coupling agent containing a mercapto, disulfide, tretrasulfide and/or polysulfide end group provides a mercury removal media having increased reactivity, stability, and mercury removal ability. The mercury removal media described herein is prepared by reacting an organophilic clay containing onium ions with a mercapto, disulfide, tetrasulfide, and/or polysulfide end moiety. Alternatively, the clay can be made organophilic by onium ion reaction prior to or simultaneously with the coupling reaction of the mercapto- or sulfide-end group-containing coupling agent.

Abstract: The use of a sulfur-impregnated organoclay provides a mercury or arsenic removal media having increased reactivity, stability, and mercury removal ability. The Hg/As removal media described herein is prepared by impregnating an organophilic clay with elemental (free state) sulfur. Alternatively, the clay can be made organophilic by onium ion reaction prior to or simultaneously with impregnating the organoclay with sulfur.

Abstract: The use of a sulfur-impregnated organoclay provides a mercury or arsenic removal media having increased reactivity, stability, and mercury removal ability. The Hg/As removal media described herein is prepared by impregnating an organophilic clay with elemental (free state) sulfur. Alternatively, the clay can be made organophilic by onium ion reaction prior to or simultaneously with impregnating the organoclay with sulfur.

Abstract: The use of a coupling agent containing a mercapto, disulfide, tretrasulfide and/or polysulfide end group provides a mercury removal media having increased reactivity, stability, and mercury removal ability. The mercury removal media described herein is prepared by reacting an organophilic clay containing onium ions with a mercapto, disulfide, tetrasulfide, and/or polysulfide end moiety. Alternatively, the clay can be made organophilic by onium ion reaction prior to or simultaneously with the coupling reaction of the mercapto- or sulfide- end group-containing coupling agent.

Abstract: An integrated circuit (IC) package having a spark gap feature for electro static discharge protection is disclosed. The IC package includes an integrated circuit package substrate. An integrated circuit die is placed on the package substrate. Also on the package substrate are a first lead trace connected to the integrated circuit die and a second lead trace adjacent the first lead trace. The second lead trace is also connected to the integrated circuit die. The second lead trace has a spark gap feature allowing at least a portion of electro static spike on the second lead trace to jump to the first lead trace. The spark gap feature can be implemented in various ways including a protrusion from the second lead trace to the first lead trace, the protrusion having a sharp vertex proximal to the first lead trace.

Abstract: The invention provides an isolated nucleic acid molecule having substantially the same nucleotide sequence as SEQ ID NO:1. Also provided is an isolated oligonucleotide having at least 15 contiguous nucleotides of a nucleotide sequence referenced as SEQ ID NO:11. An isolated polypeptide having substantially the same amino acid sequence as SEQ ID NO:2 is further provided as well as an antibody, or antigen binding fragment thereof, which specifically binds to an ATX polypeptide and has an amino acid sequence as referenced in SEQ ID NO:2. A method for identifying an ATX-modulatory compound is additionally provided. The method consists of measuring the level of an ATX polypeptide in the presence of a test compound, wherein a difference in the level of said ATX polypeptide in the presence of said test compound compared to in the absence of said test compound indicating that said test compound is an ATX-modulatory compound, and wherein said ATX-modulatory compound is not caffeine or wortmannin.

Abstract: Circuit for generating a spread spectrum clock (CGSSC) that employs a mechanism to modulate the input voltage (V_ctrl) to the VCO to achieve dithering. The CGSSC includes a voltage controller oscillator (VCO) that generates an output signal (F_out). The VCO includes an input coupled to a voltage control node for receiving a voltage signal and an output for generating a clock signal that has a frequency dependent on the received voltage signal. A VCO input voltage modulation mechanism (VIVMM) is coupled to the voltage control node (V_ctrl) for modulating or adjusting the voltage at the VCO input voltage node in a controlled manner to generate a spread spectrum clock.

Abstract: The present invention provides an assay for the identification of agents which can modulate TOR-mediated phosphorylation of substrate proteins. The assays of the invention utilize substrate proteins whose amino acid sequence contains the Ser/Thr motif recognized by TOR. Naturally occurring TOR which may be used in the methods of the invention include TOR isolated from a variety of species, particularly mammalian tissues.

Abstract: An integrated circuit (IC) package having a spark gap feature for electro static discharge protection is disclosed. The IC package includes an integrated circuit package substrate. An integrated circuit die is placed on the package substrate. Also on the package substrate are a first lead trace connected to the integrated circuit die and a second lead trace adjacent the first lead trace. The second lead trace is also connected to the integrated circuit die. The second lead trace has a spark gap feature allowing at least a portion of electro static spike on the second lead trace to jump to the first lead trace. The spark gap feature can be implemented in various ways including a protrusion from the second lead trace to the first lead trace, the protrusion having a sharp vertex proximal to the first lead trace.

Abstract: Circuit for generating a spread spectrum clock (CGSSC) that employs a mechanism to modulate the input voltage (V_ctrl) to the VCO to achieve dithering. The CGSSC includes a voltage controller oscillator (VCO) that generates an output signal (F_out). The VCO includes an input coupled to a voltage control node for receiving a voltage signal and an output for generating a clock signal that has a frequency dependent on the received voltage signal. A VCO input voltage modulation mechanism (VIVMM) is coupled to the voltage control node (V_ctrl) for modulating or adjusting the voltage at the VCO input voltage node in a controlled manner to generate a spread spectrum clock.

Abstract: A method of inhibiting restenosis in a subject following coronary angioplasty, atherectomy, or arterial bypass graft surgery comprised of administering wortmannin analogs of the present invention is described herein.

Abstract: Hydrophilic, water insoluble, organic solvent soluble polymers of hydroxyalkyl methacrylate or acrylate of high purity are prepared in water using hydroxyalkyl methacrylate or acrylate monomer having not over 0.035 weight percent of alkylene glycol dimethacrylate or diacrylate. The polymers have high molecular weight and narrow molecular weight distribution and are useful for medical applications, e.g., as a burn dressing.