Patents by Inventor Robert Andrew Harrison

Robert Andrew Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Devices and methods for pharmacokinetic-based cell culture system
    Patent number: 9732316
    Abstract: A cell culture device comprising a microscale chamber dimensioned to maintain a cell under conditions that give rise to a value for at least one pharmacokinetic parameter in vitro that is comparable to a value for the same at least one pharmacokinetic parameter obtained with respect to the same type of cell in vivo, wherein the microscale chamber is configured for flow of culture medium, and wherein the at least one pharmacokinetic parameter is selected from tissue size ratio, tissue to blood volume ratio, drug residence time, flow rate, circulatory transit time, liquid residence time, and liquid to cell ratio.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: August 15, 2017
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • DEVICES AND METHODS FOR PHARMACOKINETIC-BASED CELL CULTURE SYSTEM
    Publication number: 20160281048
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Application
    Filed: February 26, 2016
    Publication date: September 29, 2016
    Applicant: Cornell University
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and methods for pharmacokinetic-based cell culture system
    Patent number: 9273276
    Abstract: A cell culture method using an in vitro microscale cell culture device having a first microscale chamber containing cells attached to an inner surface of the chamber and cell culture medium in contact with the cells. The cells are maintained in culture in the in vitro microscale cell culture device while flowing culture medium through the first chamber at a controlled rate to provide a liquid residence time value for the cells in the first chamber of the in vitro microscale cell culture device that is comparable to a liquid residence time value obtained with respect to comparable cells in vivo, such that metabolism by the cells in culture in the in vitro microscale cell culture device is comparable to metabolism by comparable cells in vivo.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: March 1, 2016
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and Methods for Pharmacokinetic-Based Cell Culture System
    Publication number: 20120214189
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Application
    Filed: November 21, 2011
    Publication date: August 23, 2012
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and methods for pharmacokinetic-based cell culture system
    Patent number: 8030061
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: October 4, 2011
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • DEVICES AND METHODS FOR PHARMACOKINETIC-BASED CELL CULTURE SYSTEM
    Publication number: 20100304355
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Application
    Filed: September 8, 2006
    Publication date: December 2, 2010
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and Methods for Pharmacokinetic-Based Cell Culture System
    Publication number: 20080166795
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Application
    Filed: October 26, 2007
    Publication date: July 10, 2008
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and Methods for Pharmacokinetic-Based Cell Culture System
    Publication number: 20080166794
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Application
    Filed: October 26, 2007
    Publication date: July 10, 2008
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and methods for pharmacokinetic-based cell culture system
    Patent number: 7288405
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: October 30, 2007
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers
  • Devices and methods for pharmacokinetic-based cell culture system
    Publication number: 20030082795
    Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
    Type: Application
    Filed: April 25, 2002
    Publication date: May 1, 2003
    Inventors: Michael Shuler, Gregory T. Baxter, Aaron Sin, Robert Andrew Harrison, Scott Meyers