Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.

Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The present invention relates to Tau-binding antibodies and binding fragments thereof.

Abstract: The invention relates to fusion proteins which bind to human Fc-receptors. The fusion proteins are initially produced as monomers, and are capable of assembly into multimers at a target site of interest. The invention also relates to therapeutic compositions comprising the fusion proteins, and their widespread use in the treatment of diseases.

Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.

Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.

Abstract: The invention relates to multimeric proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune and other disorders.

Abstract: Optical devices are disclosed consisting of optical chips (planar lightwave circuits) which have optically symmetric or matching designs and properties and optical components which create asymmetry in the optical devices. The devices find application in detection in coherent and non-coherent optical communications systems.

Abstract: Optical devices are disclosed consisting of optical chips (planar lightwave circuits) which have optically symmetric or matching designs and properties and optical components which create asymmetry in the optical devices. The devices find application in detection in coherent and non-coherent optical communications systems.

Abstract: An improved method is provided for fabricating a polarisation rotator in a rib waveguide having a propagation axis and opposite side walls. The method includes etching a pit in the substrate surface to form a recess in one of the side walls of the waveguide, during formation of the waveguide on the substrate surface, so as to provide an asymmetric waveguide section for imparting polarisation rotation to radiation propagated along the propagation axis. Preferably the pit is formed by a wet etching step forming an upper side surface within the recess that is inclined relative the waveguide side walls, and the waveguide side walls are formed by a dry etching step to extend perpendicularly to the substrate surface. In addition the dry etching step forms a lower side surface adjoining the upper side surface within the recess and tilted relative to the upper side surface.

Abstract: An optical pulse train generator (2) for use in the transmission of high speed optical data in a return-to-zero (RZ) signalling format is described.

Abstract: A signal time-scaling arrangement utilises a known configuration comprising the use of a laser which has its wavelength varied over time, a modulator coupled to the laser and to a modulating analogue electrical source and a dispersion means coupled to the output of the modulator and providing at its output a signal which is a stretched version of the analogue modulating signal, but provides for the modulator to be a single-sideband modulator instead of double-sideband. The effect of this is to enable the use of a much simple laser-control system involving a CW laser output which is wavelength-ramped continuously between quite narrow wavelength limits, while allowing the use of a dispersion means having a wide dispersion characteristic in order to provide the required degree of time-scaling. The invention is application to an ADC system or to a Doppler system.

Abstract: An analogue-to-digital conversion arrangement employs a CW laser, which is ramped in wavelength over a given wavelength range for a given time, to drive a modulator whose modulating input is an analogue signal to be converted. The modulator feeds wavelength-splitter having a number of channels centered on different wavelengths within the wavelength range, the outputs of these channels being converted into respective analogue electrical signals, conventional ADCs being finally used to convert these signals in turn into digital signals.

Abstract: The use of multi-level signalling in optical links may provide an improvement in system capacity compared to conventional binary signalling. Unlike conventional electronic or radio systems, in optically amplified links where optical noise is dominant equally spaced signalling levels are not optimum. For these links, the use of signalling levels with quadratic spacing can provide the lowest bit error rate for a given signal power, allowing a 6 dB reduction in launched optical power. The invention described is an arrangement to produce multi-level optical signalling with quadratic spacing. A multi-level optical signal generator for generating a multi-level optical signal in optical links in response to two or mote electrical signals. A light source arrangement provides a respective optical signal for each electrical signal utilising either separate light sources corresponding to each electrical signal or preferably, a single light source and a beam splitter.

Abstract: A signal time-scaling arrangement utilises a known configuration comprising the use of a laser which has its wavelength varied over time, a modulator coupled to the laser and to a modulating analogue electrical source and a dispersion means coupled to the output of the modulator and providing at its output signal which is a stretched version of the analogue modulating a signal, but provides for the modulator to be a single-sideband modulator instead of double-sideband. The effect of this is to enable the use of a much simple laser-control system involving a CW laser output which is wavelength-ramped continuously between quite narrow wavelength limits, while allowing the use of a dispersion means having a wide dispersion characteristic in order to provide the required degree of time-scaling. The invention is application to an ADC system or to a Doppler system.