Patents by Inventor Robert B. Reynolds

Robert B. Reynolds has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant proteolytic enzymes and method of production
    Patent number: 6403331
    Abstract: Mutant Bacillus lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: May 31, 2000
    Date of Patent: June 11, 2002
    Assignee: Henkel Konnarditgesellshaft auf Aktien
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang
  • Mutant proteolytic enzymes and method of production
    Patent number: 6136553
    Abstract: Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: October 24, 2000
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang
  • Mutant proteolytic enzymes and method of production
    Patent number: 5985639
    Abstract: Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: March 19, 1996
    Date of Patent: November 16, 1999
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang
  • Bacillus lentus alkaline protease varints with enhanced stability
    Patent number: 5500364
    Abstract: Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: March 19, 1996
    Assignee: Cognis, Inc.
    Inventors: Teresa Christianson, Dean Goddette, Beth F. Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang
  • Alkaline proteolytic enzyme and method of production
    Patent number: 5352604
    Abstract: A proteolytic enzyme for use in detergent formulations having increased pH and oxidative stability under typical laundering conditions in aqueous solutions is produced by fermenting Bacillus licheniformis host strain transformed by a multicopy plasmid comprised of DNA sequences which code for the desired proteolytic enzyme.
    Type: Grant
    Filed: March 10, 1993
    Date of Patent: October 4, 1994
    Assignee: Henkel Research Corporation
    Inventors: Charles R. Wilson, Beth F. Ladin, Jonathan R. Mielenz, Sherman S. M. Hom, Dieter Hansen, Robert B. Reynolds, Nicholas C. T. Kennedy, Joachim Schindler, Michael Bahn, Rolf Schmid, Martina Markgraf, Christian Paech, Karlheinz Maurer
  • Bacillus lentus alkaline protease variants with increased stability
    Patent number: 5340735
    Abstract: Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: May 29, 1991
    Date of Patent: August 23, 1994
    Assignee: COGNIS, Inc.
    Inventors: Teresa Christianson, Dean Goddette, Beth F. Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang